HOME >> MEDICINE >> NEWS
Common osteoporosis treatment may help men with prostate cancer suffering from bone loss

SAN FRANCISCO, Feb. 25 Men with prostate cancer who experience bone loss from cancer treatment could benefit from a weekly oral therapy commonly given to women with osteoporosis, according to a study presented by the University of Pittsburgh Medical Center (UPMC) at the American Society of Clinical Oncology Prostate Cancer Symposium, Feb. 24 to 26 at the San Francisco Marriott. The study, abstract number 139, will be featured in a press program at the meeting, 7:30 a.m., Sunday, Feb. 26.

"In previous studies, we have determined that men who receive androgen deprivation therapy, a frequently used treatment for prostate cancer, suffer from severe drops in bone mass and are at an increased risk for fracture," said study principal investigator Susan Greenspan, M.D., professor of medicine, University of Pittsburgh and director, Osteoporosis Prevention and Treatment Center, UPMC. "In an attempt to mitigate these effects, we gave men using this therapy a once-weekly oral agent called alendronate that is commonly used to treat osteoporosis. We found that men who received it had significantly increased bone mass compared to those who did not receive the therapy."

The study included 112 men with prostate cancer with an average age of 71. After an average of two years androgen deprivation therapy for prostate cancer, only 9 percent of the men had normal bone mass, while 52 percent had low bone mass and 39 percent developed osteoporosis. To study the effect of alendronate on these men, they were randomized into two groups to receive either alendronate once a week through an orally administered pill or a placebo. At one year follow-up, bone mass in the spine and hip increased significantly in the men treated with alendronate, 4.9 percent and 2.1 percent respectively. By comparison, men in the placebo group had significant losses of bone mass in the spine and hip, 1.3 percent and .7 percent respectively. In addition, the therapy was well-tolerated and easily adm
'"/>


25-Feb-2006


Page: 1 2

Related medicine news :

1. Commonly used drug offers promise for premature babies
2. Commonly used pain medications do not prevent Alzheimers disease
3. Common anesthetic may induce cell death, generation of Alzheimers-associated protein
4. Common blood pressure drug treats muscular dystrophy in mice
5. Common PTSD drug is no more effective than placebo
6. Common cold may be just a fingertip away due to environmental contamination
7. Commonwealth Fund commission says the US health care system needs thorough transformation
8. Commonly recommended sedative does not improve infant sleep
9. Common asthma inhaler causing deaths, researchers assert
10. Common painkillers associated with increased risk of first hospital admission for heart failure
11. Commonly used blood pressure medication prevents aortic aneurysm in mice with Marfan syndrome

Post Your Comments:
(Date:7/26/2014)... As the category creator and ... of Xoçai is to transform and ... healthy chocolate products. One such unique element is ... berries and blueberries, an ingredient combination exclusive to ... utilized in all of Xoçai products and provides ...
(Date:7/25/2014)... 2014 Deep Research Report on ... Industry” is a professional and in-depth research report ... market. The report provides basic Laser Scanning Confocal ... definition, classification, application, and industry chain structure ... international market analysis, including China’s domestic market as ...
(Date:7/25/2014)... 2014 As reported by the Statesman Journal ... Heroin (7/20), police in Salem, MA as well as ... the recent heroin epidemic that has taken many lives during ... heroin-related overdose case in which police were able to make ... phone. By pretending to be the victim and claiming to ...
(Date:7/25/2014)... America (GSA) the nation,s largest interdisciplinary ... has chosen Heather M. Young, PhD, RN, FAAN, ... 2014 recipient of the Doris Schwartz Gerontological Nursing ... GSA,s Health Sciences Section, is given to a ... and sustained contribution to gerontological nursing research. , ...
(Date:7/25/2014)... and MOSI officially announced a transformational partnership that will unite ... a difference in the Tampa Bay community. Florida Hospital presented ... support needed to keep the science center moving forward. ... Theatre from film to a state-of-the-art digital 3D projection system. ... state of Florida, and it is one of the first ...
Breaking Medicine News(10 mins):Health News:Xocai-Asia Japanese Distributors in Hachioji, Japan Sanction Local Single-Source-Chocolate Investigative Report: MXI-Corp-Asia Discloses Direct-Sales Compensation Plan 2Health News:Xocai-Asia Japanese Distributors in Hachioji, Japan Sanction Local Single-Source-Chocolate Investigative Report: MXI-Corp-Asia Discloses Direct-Sales Compensation Plan 3Health News:Xocai-Asia Japanese Distributors in Hachioji, Japan Sanction Local Single-Source-Chocolate Investigative Report: MXI-Corp-Asia Discloses Direct-Sales Compensation Plan 4Health News:Laser Scanning Confocal Microscope Market: 2014 Global, China Manufacturing Bases Analysis Now at DeepResearchReports.com 2Health News:Laser Scanning Confocal Microscope Market: 2014 Global, China Manufacturing Bases Analysis Now at DeepResearchReports.com 3Health News:Laser Scanning Confocal Microscope Market: 2014 Global, China Manufacturing Bases Analysis Now at DeepResearchReports.com 4Health News:Multiple States Crack Down on Heroin Epidemic 2Health News:Young earns GSA's 2014 Doris Schwartz Gerontological Nursing Research Award 2Health News:Florida Hospital Donates a Two Million Dollar Transformational Gift to the Museum of Science and Industry (MOSI) 2Health News:Florida Hospital Donates a Two Million Dollar Transformational Gift to the Museum of Science and Industry (MOSI) 3Health News:Florida Hospital Donates a Two Million Dollar Transformational Gift to the Museum of Science and Industry (MOSI) 4
(Date:7/25/2014)... -- "Australia Capsule Endoscopy Systems Market Outlook to 2020″, ... Systems market. The report provides value, in millions of ... US dollars) within market segments: Photo - ... , Capsule Endoscopy Data Recorders , Capsule ... company shares and distribution shares data for each of ...
(Date:7/25/2014)... , July 25, 2014 /PRNewswire-iReach/ -- Full Service ... as the new Vice President of Business Development. Peter ... years in a number of different business development positions ... These positions were primarily related to business development/sales management ... past 30 years makes him a key and strategic ...
(Date:7/25/2014)... Cardinal Health will today name three of the nation,s ... Independent Pharmacy Best Practices Competition, during the company,s ... gatherings of independent pharmacists. The Best ... Ohio , Tennessee and ... implementing exceptionally creative methods that demonstrate how independent pharmacies ...
Breaking Medicine Technology:Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 2Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 3Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 4Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 5Contract Research Organization WCCT Global Welcomes Peter Nieto as Vice President of Business Development 2Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 2Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 3Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 4Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 5Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 6
Cached News: