HOME >> MEDICINE >> NEWS
Commonly used pain medications do not prevent Alzheimer's disease

ST. PAUL, Minn Over-the-counter pain medication naproxen and prescription pain reliever celecoxib do not prevent Alzheimer's disease, according to a study published April 25, 2007, in the online edition of Neurology, the scientific journal of the American Academy of Neurology. These findings appear to contradict earlier observational studies, which found sustained use of nonsteroidal anti-inflammatory drugs (NSAIDs) may have a protective effect against Alzheimer's disease.

The clinical trial, conducted at six dementia research clinics across the United States, involved more than 2,100 people over age 70 with no signs of dementia, but a family history of Alzheimer's disease. The participants were randomly assigned daily doses of naproxen, celecoxib, or placebo for up to four years, but most participants had received the treatments for less than two years.

The study found neither treatment was associated with a reduction in Alzheimer's disease or dementia.

"Although our study was conducted to test the hypothesis that celecoxib or naproxen would reduce the incidence of Alzheimer's disease, these results indicate no such effect, at least within the first few years after treatment begins," said study author Constantine Lyketsos, MD, MHS, with Johns Hopkins Bayview Hospital and Johns Hopkins School of Medicine in Baltimore, Maryland.

The findings appear to be inconsistent with other studies suggesting reduced risk of Alzheimer's disease among people who take NSAIDs over a long period of time. "One possible explanation for this inconsistency is that our findings relate specifically to celecoxib and naproxen, but not to other commonly used NSAIDs, such as ibuprofen. Or the drugs may not prevent the progression of disease in people who have advanced Alzheimer's pathology without symptoms the very people most likely to develop symptoms within a year or two," said study author John C. S. Breitner, MD, with VA Puget Sound Health
'"/>

Contact: Angela Babb
ababb@aan.com
651-695-2789
American Academy of Neurology
25-Apr-2007


Page: 1 2

Related medicine news :

1. Commonly used drug offers promise for premature babies
2. Commonly recommended sedative does not improve infant sleep
3. Commonly used blood pressure medication prevents aortic aneurysm in mice with Marfan syndrome
4. Commonly used drug may prevent fetal alcohol syndrome
5. Commonly used antidepressants may also affect human immune system
6. Standard long-acting insulin as good as newer medications
7. MS patients not receiving medications to slow disease progression, research shows
8. Cost control measures limit patient and physician choice in psychotropic medications
9. Improved adherence to certain medications associated with longer survival following heart attack
10. Antipsychotic medications used to treat Alzheimers patients found lacking
11. Second-generation antipsychotic medications appear to offer little advantage over older drugs

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/4/2020)... ... July 03, 2020 , ... MemoryCare.com , ... announced the Best Memory Care Facilities in Charleston, South Carolina. The guide identifies ... amenities. , According to the Alzheimer’s Association , 5.6 million people ...
(Date:7/2/2020)... ... July 02, 2020 , ... The Coronavirus (COVID-19) pandemic resulted ... In conjunction with the American Dental Association and Centers for Disease Control and ... , Due to safety concerns, the announcement sparked hesitancy among some hygienists, who ...
(Date:7/1/2020)... ... July 01, 2020 , ... G-CON Manufacturing, the ... by Codiak BioSciences to support its cleanroom build out at its new clinical ... the drug substance and product manufacturing for its clinical pipeline. , Codiak chose ...
(Date:6/28/2020)... ... June 26, 2020 , ... ... workers and the general public. As a supplier of top-quality masks, sanitizers and ... source for PPE equipment. President Priya Agarwal observed, “All of our masks are ...
(Date:6/25/2020)... ... ... Denials Management, Inc. has just published The Health Insurance Appeals Guide to ... of mental health and substance use disorder (MH/SUD) treatment services. It was written by ... the steps in the appeals process. Complimentary copies of the Guide can be ...
Breaking Medicine News(10 mins):
(Date:7/7/2020)... ... July 07, 2020 , ... CHESS Health, the leading ... leading comprehensive platform for online education on mental health, substance use, and suicide ... Use Disorder (SUD) patients throughout each step of the treatment process. , “We ...
(Date:7/7/2020)... VEGAS (PRWEB) , ... July 07, 2020 , ... To ... the Women of Global Change (WGC), will be providing meals to the employees of ... different Coronavirus testing sites throughout Las Vegas on Wednesday, July 8th. , When asked ...
(Date:7/7/2020)... ... July 07, 2020 , ... SupplyPro announces a Contact Tracing function available ... affecting every one of us. SupplyPro is dedicated to supporting the worldwide response to ... Tracing Report - a powerful tool in the fight against the spread of COVID-19. ...
Breaking Medicine Technology:
Cached News: