HOME >> MEDICINE >> NEWS
Comparison of drug-releasing coronary stents show similar effectiveness

Use of coronary stents that release the drugs sirolimus or paclitaxel produced similar results in patients with new coronary artery lesions, according to a study in the February 22 issue of JAMA.

Stents that release sirolimus or paclitaxel have been known to be more effective than bare metal stents in improving angiographic (examination of the blood vessels using x-rays) and clinical outcomes after percutaneous coronary revascularization (procedures such as angioplasty in which a catheter-guided balloon is used to open a narrowed coronary artery). These drugs are effective after these procedures because they inhibit the growth of cells in blood vessels. It has not been clear if one drug-releasing stent is more effective than another, according to background information in the article.

Marie-Claude Morice, M.D., of the Institut Cardiovasculaire Paris Sud, Massy, France and colleagues compared the safety and efficacy of sirolimus-eluting vs. paclitaxel-eluting coronary stents in patients with new coronary artery lesions. The REALITY trial included 1,386 patients with angina pectoris (a heart condition marked by chest pain due to reduced blood flow to the heart) and 1 or 2 new coronary lesions. The study was conducted at 90 hospitals in Europe, Latin America, and Asia between August 2003 and February 2004, with angiographic follow-up at 8 months and clinical follow-up at 12 months. Patients were randomly assigned to receive a sirolimus-eluting (releasing) stent or a paclitaxel-eluting stent.

The researchers found that the average restenosis (narrowing again of a coronary artery after treatment) rate, the primary study outcome the researchers were using to compare the stents, was 9.6 percent in the sirolimus-eluting stent group vs. 11.1 percent in the paclitaxel-eluting stent group, a difference that did not reach statistical significance. Likewise, there were no significant differences between the 2 study groups in rates of other in-hospital ad
'"/>

Contact: Marie-Claude Morice, M.D.
mc.morice@icps.com.fr
JAMA and Archives Journals
21-Feb-2006


Page: 1 2

Related medicine news :

1. Comparison of obstetric outcomes between on-call and patients own obstetricians
2. Comparison of patients access to new and better cancer drugs reveals inequalities between countries
3. Comparison of 4 diet plans shows better outcomes for diet with lowest carbohydrate intake
4. New biodegradable magnesium stents for coronary arteries
5. Same-day coronary angiography and surgery safe for many patients
6. Experts debate role of stenting, bypass surgery in left main coronary artery disease
7. Acute coronary syndrome therapy improvements linked with fewer deaths and improved clinical outcomes
8. Exercise can cut coronary artery disease risk for some with MS
9. Having elevated risk factors in young adulthood raises risk of coronary calcium later on
10. Study finds coronary procedure adds no benefit over optimal medical therapy alone
11. Pairing medical therapy with coronary intervention fails to reduce heart disease deaths

Post Your Comments:
(Date:7/29/2014)... 2014)A diet rich in soy may help feminine hearts, ... today in Menopause , the journal of The ... to the diet of women in Asia, produces the ... similar to Asian migrants to North America, leads to ... and switching to soy from a Western diet after ...
(Date:7/29/2014)... July 29, 2014 Daily Gossip indicates in ... method was created for any sufferer who is looking for ... The author of the new program, Sarah Summer, says that ... suffered from yeast infection, too. Actually, this is the reason ... this problem. , The Natural Cure for Yeast ...
(Date:7/29/2014)... Port Washington, New York (PRWEB) July 29, 2014 ... dedicated to protecting the rights of victims injured by ... action lawsuit has been filed by plaintiffs in Canada ... increased risk of cardiovascular events with the low ... was filed on July 22, 2014 in the Ontario ...
(Date:7/29/2014)... Regardless of the good things that ... to share those with. Love is about understanding, commitment ... Love is also about overcoming all the challenges that ... perfect relationship, women need to know how to understand ... Him program, please visit the official website at ...
(Date:7/29/2014)... of severe combat injuries threatening more than one limb, ... record of safety and effectiveness in avoiding amputation, reports ... Plastic and Reconstructive Surgery , the official medical ... (ASPS). , Experience with multiple limb salvage procedures ... success rates, with no increase in complications compared to ...
Breaking Medicine News(10 mins):Health News:Soy may help women's hearts if they start early 2Health News:Natural Cure for Yeast Infection Review Reveals Sarah Summer’s Healing Method 2Health News:Class Action Lawsuit in Canada Alleges Manufacturer of Delatestryl Testosterone Injection Failed to Warn of Cardiovascular Risks, Parker Waichman LLP Reports 2Health News:Class Action Lawsuit in Canada Alleges Manufacturer of Delatestryl Testosterone Injection Failed to Warn of Cardiovascular Risks, Parker Waichman LLP Reports 3Health News:How to Reach the Heart of the Perfect Guy with "Enchant Him Program" - a Report by Daily Gossip Magazine 2Health News:Good outcomes with multiple limb salvage after severe combat injuries, reports Plastic and Reconstructive Surgery 2
(Date:7/29/2014)...  EnteroMedics Inc. (NASDAQ: ETRM ), the ... obesity, metabolic diseases and other gastrointestinal disorders, today announced ... August 7, 2014 at 11:00 AM Eastern Time to ... 30, 2014 and to provide a business update. ... conference call may be accessed by dialing (877) 280-7473 ...
(Date:7/29/2014)... 29, 2014 New high priced hepatitis C ... by a projected $2.9 to $5.8 billion next year, ... Milliman released today by the Pharmaceutical Care Management Association ... increase by as much as 8.6 percent in 2015 ... Sovaldi and Olysio. The study finds that ...
(Date:7/29/2014)... and NEW YORK , ... of the executive management team of Caremark Rx, ... Media ( www.pbm365.com ).  PBM365 is the leading independent ... reporting, insight, analysis and opinion on the pharmacy ... will provide insightful and timely coverage of, and context ...
Breaking Medicine Technology:EnteroMedics to Host Second Quarter 2014 Financial Results and Business Update Conference Call 2EnteroMedics to Host Second Quarter 2014 Financial Results and Business Update Conference Call 3New Milliman Study: Hepatitis C Drugs Could Increase Medicare Part D Spending by $2.9 to $5.8 Billion in 2015 2Drew Crawford Announces Launch of PBM365 Media 2
Cached News: