HOME >> MEDICINE >> NEWS
Comparison of drug-releasing coronary stents show similar effectiveness

Use of coronary stents that release the drugs sirolimus or paclitaxel produced similar results in patients with new coronary artery lesions, according to a study in the February 22 issue of JAMA.

Stents that release sirolimus or paclitaxel have been known to be more effective than bare metal stents in improving angiographic (examination of the blood vessels using x-rays) and clinical outcomes after percutaneous coronary revascularization (procedures such as angioplasty in which a catheter-guided balloon is used to open a narrowed coronary artery). These drugs are effective after these procedures because they inhibit the growth of cells in blood vessels. It has not been clear if one drug-releasing stent is more effective than another, according to background information in the article.

Marie-Claude Morice, M.D., of the Institut Cardiovasculaire Paris Sud, Massy, France and colleagues compared the safety and efficacy of sirolimus-eluting vs. paclitaxel-eluting coronary stents in patients with new coronary artery lesions. The REALITY trial included 1,386 patients with angina pectoris (a heart condition marked by chest pain due to reduced blood flow to the heart) and 1 or 2 new coronary lesions. The study was conducted at 90 hospitals in Europe, Latin America, and Asia between August 2003 and February 2004, with angiographic follow-up at 8 months and clinical follow-up at 12 months. Patients were randomly assigned to receive a sirolimus-eluting (releasing) stent or a paclitaxel-eluting stent.

The researchers found that the average restenosis (narrowing again of a coronary artery after treatment) rate, the primary study outcome the researchers were using to compare the stents, was 9.6 percent in the sirolimus-eluting stent group vs. 11.1 percent in the paclitaxel-eluting stent group, a difference that did not reach statistical significance. Likewise, there were no significant differences between the 2 study groups in rates of other in-hospital ad
'"/>

Contact: Marie-Claude Morice, M.D.
mc.morice@icps.com.fr
JAMA and Archives Journals
21-Feb-2006


Page: 1 2

Related medicine news :

1. Comparison of obstetric outcomes between on-call and patients own obstetricians
2. Comparison of patients access to new and better cancer drugs reveals inequalities between countries
3. Comparison of 4 diet plans shows better outcomes for diet with lowest carbohydrate intake
4. New biodegradable magnesium stents for coronary arteries
5. Same-day coronary angiography and surgery safe for many patients
6. Experts debate role of stenting, bypass surgery in left main coronary artery disease
7. Acute coronary syndrome therapy improvements linked with fewer deaths and improved clinical outcomes
8. Exercise can cut coronary artery disease risk for some with MS
9. Having elevated risk factors in young adulthood raises risk of coronary calcium later on
10. Study finds coronary procedure adds no benefit over optimal medical therapy alone
11. Pairing medical therapy with coronary intervention fails to reduce heart disease deaths

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/5/2016)... ... 05, 2016 , ... What: Shriners Hospitals for Children, with the help of ... – using a video monitor and web-enabled camera. Santa visits with children through Dimension ... a Christmas Wonderland, which is where the video connection to the North Pole will ...
(Date:12/5/2016)... Austin, TX (PRWEB) , ... December 05, 2016 ... ... Center for Facial Plastic Surgery, is excited to announce the arrival of the ... hybrid fractional laser, with the ability to use tunable non-ablative and ablative wavelengths ...
(Date:12/5/2016)... ... December 06, 2016 , ... For many years, Andrew ... both thick and thin. The beauty of the Lithuanian language and its ... In this poetry book, Zubinas lyrically explores all aspects of a living, breathing forest ...
(Date:12/5/2016)... (PRWEB) , ... December 05, ... ... and security executive networking and relationship-marketing firm, announced today that nominations will ... 2017 Information Security Executive® (ISE®) Central Awards. , Awards include the Information ...
(Date:12/5/2016)... ... 05, 2016 , ... Worldwise ®, a leading consumer ... kathy ireland® Worldwide for five additional years, announced by Kevin Fick, Worldwise CEO. ... agreement three years ago to design and develop the kathy ireland® Loved Ones™ ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... 2016  New research by the CVS Health ... the U.S. Department of Health and Human Services, ... Response (ASPR), published online today in JAMA ... encourage patients with chronic conditions to refill medications ... also affirms that public-private partnerships can facilitate timely ...
(Date:12/5/2016)... NORTHBROOK, Ill. , Dec. 5, 2016 ... perfect score on the 2017 Human Rights Campaign ... (CEI). The CEI is a national benchmarking tool used ... gay, bisexual, and transgender (LGBT) employee equality. ... CEI Survey to help companies gauge their equality efforts, ...
(Date:12/5/2016)...  John Seng, founder of Spectrum Science Communications , announced ... Executive Officer following two consecutive years of high double digit growth ... in 2014 and assumed management of the firm that Seng founded ... as Healthcare Agency of the Year and was selected among the ... ...
Breaking Medicine Technology:
Cached News: