HOME >> MEDICINE >> NEWS
Comparison of drug-releasing coronary stents show similar effectiveness

Use of coronary stents that release the drugs sirolimus or paclitaxel produced similar results in patients with new coronary artery lesions, according to a study in the February 22 issue of JAMA.

Stents that release sirolimus or paclitaxel have been known to be more effective than bare metal stents in improving angiographic (examination of the blood vessels using x-rays) and clinical outcomes after percutaneous coronary revascularization (procedures such as angioplasty in which a catheter-guided balloon is used to open a narrowed coronary artery). These drugs are effective after these procedures because they inhibit the growth of cells in blood vessels. It has not been clear if one drug-releasing stent is more effective than another, according to background information in the article.

Marie-Claude Morice, M.D., of the Institut Cardiovasculaire Paris Sud, Massy, France and colleagues compared the safety and efficacy of sirolimus-eluting vs. paclitaxel-eluting coronary stents in patients with new coronary artery lesions. The REALITY trial included 1,386 patients with angina pectoris (a heart condition marked by chest pain due to reduced blood flow to the heart) and 1 or 2 new coronary lesions. The study was conducted at 90 hospitals in Europe, Latin America, and Asia between August 2003 and February 2004, with angiographic follow-up at 8 months and clinical follow-up at 12 months. Patients were randomly assigned to receive a sirolimus-eluting (releasing) stent or a paclitaxel-eluting stent.

The researchers found that the average restenosis (narrowing again of a coronary artery after treatment) rate, the primary study outcome the researchers were using to compare the stents, was 9.6 percent in the sirolimus-eluting stent group vs. 11.1 percent in the paclitaxel-eluting stent group, a difference that did not reach statistical significance. Likewise, there were no significant differences between the 2 study groups in rates of other in-hospital ad
'"/>

Contact: Marie-Claude Morice, M.D.
mc.morice@icps.com.fr
JAMA and Archives Journals
21-Feb-2006


Page: 1 2

Related medicine news :

1. Comparison of obstetric outcomes between on-call and patients own obstetricians
2. Comparison of patients access to new and better cancer drugs reveals inequalities between countries
3. Comparison of 4 diet plans shows better outcomes for diet with lowest carbohydrate intake
4. New biodegradable magnesium stents for coronary arteries
5. Same-day coronary angiography and surgery safe for many patients
6. Experts debate role of stenting, bypass surgery in left main coronary artery disease
7. Acute coronary syndrome therapy improvements linked with fewer deaths and improved clinical outcomes
8. Exercise can cut coronary artery disease risk for some with MS
9. Having elevated risk factors in young adulthood raises risk of coronary calcium later on
10. Study finds coronary procedure adds no benefit over optimal medical therapy alone
11. Pairing medical therapy with coronary intervention fails to reduce heart disease deaths

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is underway. ... ambulance transport experience for the millions of people who require these medical transport ... taxi industry through the use of technology. Now, SmartEMS has put forth an ...
(Date:6/26/2016)... ... , ... PawPaws brand pet supplements owned by Whole Health Supply ... health of felines. The formula is all-natural and is made from Chinese herbs that ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root ...
(Date:6/25/2016)... ... ... Bruton Memorial Library on June 21 due to a possible lice infestation, as reported by ... lice: the parasite’s ability to live away from a human host, and to infest common ... the event that lice have simply gotten out of control. , As lice are a ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health ... of their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards ... at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her son ... lash out at his family verbally and physically. , “When something upset him, he couldn’t ... would use it. He would throw rocks at my other children and say he was ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Belgium , June 24, 2016 ... today announced the appointment of Dr. Edward ... as a Non-Executive Director, effective June 23, 2016.Dr. ... Compensation and Nominations and Governance Committees.  As a ... will provide independent expertise and strategic counsel to ...
(Date:6/23/2016)... , June 23, 2016 Research ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, ... (Oral, Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is ... a CAGR of 6.1% in the forecast period 2016 ...
(Date:6/23/2016)... , June 23, 2016 Research and ... News Issue 52" report to their offering. ... influenza treatment creates a favourable commercial environment for MedImmune to ... patient base that will serve to drive considerable growth for ... would serve to cap sales considerably, but development is still ...
Breaking Medicine Technology:
Cached News: