HOME >> MEDICINE >> NEWS
Cool therapy reduces brain injury and death from oxygen loss in newborns

Infants born with oxygen loss who are given an innovative therapy that lowers their entire body temperature by four degrees within the first six hours of life, have a better chance of survival and lower incidence of brain injury, according to a report in the October 13 issue of the New England Journal of Medicine.

"We speculate that this therapy lowers the brain temperature as well as body temperature and slows down the injury process caused by birth asphyxia, which results in loss of oxygen to the brain," said Yale researcher Richard A. Ehrenkranz, M.D., professor of pediatric neonatology and obstetrics and gynecology at Yale School of Medicine and Yale-New Haven Hospital. "Less injury means a better outcome and fewer cases of cerebral palsy and other complications."

Ehrenkranz co-authored the study with colleagues at 14 other institutions in the National Institute of Child Health and Human Development Neonatal Research Network.

Hypoxic ischemic encephalopathy (HIE) occurs when an infant's brain fails to receive sufficient oxygen or blood before birth. The condition may occur hours before birth or during labor and delivery. It can be caused by complications such as compression or tearing of the placenta or the umbilical cord and rupture of the uterus. Many infants who survive HIE experience brain disability.

The team, led by Seetha Shankaran, M.D., at Wayne State University studied the effect of hypothermia or reduced body temperature, in full-term infants with asphyxia and related complications at birth. Researchers randomly assigned 208 infants to either a control group or a whole-body cooling group where their body temperature was kept at 92.3 degrees for 72 hours, then slowly re-warmed. Body temperatures were lowered by placing babies on a blanket initially filled with circulating 41-degree water. Both groups received standard newborn intensive care including monitoring of vital signs.

When the infants were examine
'"/>

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University
12-Oct-2005


Page: 1 2

Related medicine news :

1. Chemotherapy with bevacizumab increases risk of blood clots in arteries
2. Nonsmall cell lung cancer -- chemotherapy before surgery appears better than surgery alone
3. Stroke in nonvascular atrial fibrillation -- anti-coagulants better than anti-platelet therapy
4. Hormone therapy offers new hope for ovarian cancer patients
5. Borderline personality disorder shows improvements with intensive psychotherapy
6. Trial shows circulating tumor cells predict how prostate cancer patients do with chemotherapy
7. Chemotherapy may enhance the effectiveness of brain tumor vaccines
8. Brain-boosting pill alleviates post-chemotherapy fogginess
9. Adding radioimmunotherapy to chemo may help patients with lymphoma
10. Pre-operative chemotherapy does not increase survival rates for nonsmall cell lung cancer
11. OHSU Cancer Institute shows findings of immunotherapy vaccine in prostate cancer patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/16/2019)... ... ... At their 36th Annual Awards Gala on November 12th at The Pierre ... services benefiting Calvary patients and their families. Ryan Field, WABC-TV Sports Anchor, served as ... Shirley Alston Reeves, original lead singer of The Shirelles. , Carlos M. ...
(Date:11/16/2019)... (PRWEB) , ... November 15, 2019 , ... ... before in the United States, access to cannabis via well-managed dispensaries becomes more ... industry. Wise Business Plans, industry-leading online provider of state-of-the-art, online, custom cannabis business ...
(Date:11/15/2019)... ... November 15, 2019 , ... Anxiety ... of America (ADAA) puts the current figures of adults who suffer at ... mental health issues manifest in many different ways, including Post Traumatic Stress Disorder ...
(Date:11/15/2019)... , ... November 15, 2019 , ... ... 100 employers in Newsday’s Top Long Island Workplaces for 2019. The recently announced ... During the selection process, Newsday worked in partnership with Energage to conduct surveys ...
(Date:11/14/2019)... ... 14, 2019 , ... In a first of its kind ... have performed a pioneering coronary intervention with an Impella heart assist device ... The new procedure offers surgeons another option to help save the lives of ...
Breaking Medicine News(10 mins):
(Date:11/15/2019)... , ... November 15, 2019 , ... Unlike fine wine, ... most notably, shoulder impingement syndrome and rotator cuff disease – rise after age 50, ... the upper limbs. , Impingement syndrome occurs when the uppermost tendon of the rotator ...
(Date:11/15/2019)... ... , ... Mold doesn’t need things to be wet in order to grow; ... the eye or by touch. ServPro in Cayucos , the mold damage specialist, ... conditions that mold needs to grow and how to prevent those conditions. , Mold ...
(Date:11/14/2019)... ... November 14, 2019 , ... Algae Health ... human clinical trials using AstaZine® on brain health. , In the ... of depression, mental fatigue and overall mood state [psychological well-being] were found after ...
Breaking Medicine Technology:
Cached News: