HOME >> MEDICINE >> NEWS
Cruciferous vegetables may help some people protect against lung cancer

Eating vegetables from the cabbage family could help individuals with a certain genetic make-up reduce their risk of lung cancer, suggests a research letter in this week's issue of The Lancet.

Whether the consumption of cruciferous vegetables, such as cabbage, broccoli and sprouts, protects against lung cancer is unclear. Some observational studies have shown a protective effect. But a person's genetic status may influence or mask this effect. Cruciferous vegetables are rich in isothiocyanates, which have been shown to have strong chemopreventive properties against lung cancer. Isothiocyanates are eliminated in the body by glutathione-S-transferase enzymes produced by the genes GSTM1 and GSTT1. People who have inactive forms of these genes therefore have higher concentrations of isothiocyanates because of their reduced elimination capacity. Paul Brennan (International Agency for Cancer Research) and colleagues looked at whether the protective effect of cruciferous vegetables was most apparent in these individuals.

The investigators recruited 2141 patients with lung cancer and 2168 age and sex-matched controls from six countries in eastern and central Europe. The researchers gave participants a food questionnaire to fill in and assessed their genetic status from a blood sample. They found that weekly consumption of cruciferous vegetables had a 33% protective effect against lung cancer in people who had an inactive form of the GSTM1 gene. In people who had an inactive GSTT1 gene there was a 37% protective effect, while those with both genes inactivated had a 72% protective effect. The investigators found no protective effect in people with active forms of the genes.

Dr Brennan states: "These data provide strong evidence for a substantial protective effect of cruciferous vegetable consumption on lung cancer."


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
27-Oct-2005


Page: 1

Related medicine news :

1. International symposium on fruit, vegetables headed for Houston
2. Americans still not eating enough fruits and vegetables, according to 2 recent studies
3. 100 percent juices found as beneficial to health as fruits and vegetables
4. National Academies advisory: Native African vegetables
5. Pigments in corn, squash and other vegetables may help protect against age-related vision loss
6. Animal studies suggest vegetables may reduce hardening of arteries
7. Eating more than five portions of fruit & vegetables a day can substantially reduce risk of stroke
8. Higher consumption of some soy products, grains and vegetables linked to reduced risk of lung cancer
9. Warfarin better than aspirin at stroke prevention in elderly people with atrial fibrillation
10. Preventive treatments in elderly people needs rethinking
11. Why do people have sex?

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional ... action towards gender equality at their inaugural Summit in New York City in June. ... a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has ... today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula ... the highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... Mohebi Hair Restoration, has recently contributed a medical article to the newly revamped ... cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as Follicular ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... (HLA), the nation's first interactive health literacy software tool, and the Cancer Patient ... aspects of cancer patient education, today announce a new strategic alliance. , ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Fla. , Oct. 2, 2017  AllianceRx Walgreens ... company formed by Walgreens and pharmacy benefit manager Prime ... its new brand, which included the unveiling of new ... , as well as at a few other ... the new brand to patients, some of whom will ...
(Date:10/2/2017)... Denmark , Oct. 2, 2017 The Rebound ... in the struggle to reverse the tide of prescription drug ... for regulating their medicine intake and stepping down their dosage ... set to launch in December 2017; the first 100,000 people ... Learn more at http://www.rebound-solution.com/ ...
(Date:9/28/2017)... -- Cohen Veterans Bioscience and Early Signal Foundation announce ... home sensors for real-time monitoring of patients with trauma-related ... organization focused on disruptive health solutions for rare disorders ... to record and integrate behavioral, cognitive, physiological and contextual ... ...
Breaking Medicine Technology:
Cached News: