HOME >> MEDICINE >> NEWS
Cruciferous vegetables may help some people protect against lung cancer

Eating vegetables from the cabbage family could help individuals with a certain genetic make-up reduce their risk of lung cancer, suggests a research letter in this week's issue of The Lancet.

Whether the consumption of cruciferous vegetables, such as cabbage, broccoli and sprouts, protects against lung cancer is unclear. Some observational studies have shown a protective effect. But a person's genetic status may influence or mask this effect. Cruciferous vegetables are rich in isothiocyanates, which have been shown to have strong chemopreventive properties against lung cancer. Isothiocyanates are eliminated in the body by glutathione-S-transferase enzymes produced by the genes GSTM1 and GSTT1. People who have inactive forms of these genes therefore have higher concentrations of isothiocyanates because of their reduced elimination capacity. Paul Brennan (International Agency for Cancer Research) and colleagues looked at whether the protective effect of cruciferous vegetables was most apparent in these individuals.

The investigators recruited 2141 patients with lung cancer and 2168 age and sex-matched controls from six countries in eastern and central Europe. The researchers gave participants a food questionnaire to fill in and assessed their genetic status from a blood sample. They found that weekly consumption of cruciferous vegetables had a 33% protective effect against lung cancer in people who had an inactive form of the GSTM1 gene. In people who had an inactive GSTT1 gene there was a 37% protective effect, while those with both genes inactivated had a 72% protective effect. The investigators found no protective effect in people with active forms of the genes.

Dr Brennan states: "These data provide strong evidence for a substantial protective effect of cruciferous vegetable consumption on lung cancer."


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
27-Oct-2005


Page: 1

Related medicine news :

1. International symposium on fruit, vegetables headed for Houston
2. Americans still not eating enough fruits and vegetables, according to 2 recent studies
3. 100 percent juices found as beneficial to health as fruits and vegetables
4. National Academies advisory: Native African vegetables
5. Pigments in corn, squash and other vegetables may help protect against age-related vision loss
6. Animal studies suggest vegetables may reduce hardening of arteries
7. Eating more than five portions of fruit & vegetables a day can substantially reduce risk of stroke
8. Higher consumption of some soy products, grains and vegetables linked to reduced risk of lung cancer
9. Warfarin better than aspirin at stroke prevention in elderly people with atrial fibrillation
10. Preventive treatments in elderly people needs rethinking
11. Why do people have sex?

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... ... ... Give To Cure today announced that it is working with ... Cure’s campaign that is crowdfunding clinical trials to help find cures faster for Alzheimer’s ... smart device. In 2015 alone, Venmo processed $7.5 billion in transactions among users. , ...
(Date:2/5/2016)... , ... February 05, 2016 , ... ... #3 in the 2015 Best in KLAS: Software & Services for HIT Implementation ... Best in KLAS report independently ranks vendor performance by healthcare executives, managers and ...
(Date:2/5/2016)... ... , ... Dr. Justin Scott and Dr. Lydia Muccioli of Pure Dental ... individuals in need. The event is scheduled to take place on February 27, 2016 ... provide dental care to community members in need. Each patient will be given the ...
(Date:2/5/2016)... ... February 05, 2016 , ... Dr. Ben Amini, ... it is now welcoming orthodontist, Dr. Amanda Cheng, to the practice. With the ... oral health care, including general dentistry, cosmetic treatments, periodontics, implant dentistry , ...
(Date:2/5/2016)... ... February 05, 2016 , ... In sleep, when the defenses of the ... hallmark feature of patients with eating disorders is significant self-criticism, and consequently these patients ... obsessions are regarded as maladaptive means for coping with this unease, but also leads ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... Feb. 5, 2016  Patients in Alabama ... ultrasound (HIFU) therapy no longer have to travel out of ... partnership with Urology Centers of Alabama to provide ... procedure for qualifying patients. Alabama ... the treatment of prostate cancer using many different modalities. They ...
(Date:2/5/2016)... ALBANY, New York , February 5, 2016 /PRNewswire/ ... A new Transparency Market Research report states that the ... bn in 2014 and is predicted to reach US$185.9 ... a CAGR of 6.50% from 2014 to 2020. The ... Market: (Branded/Generic/Over-the-counter, Chemical/Biological, Captive/Contract Manufactured, by Geography, and by ...
(Date:2/5/2016)... -- Site Profile: --> ... Speech Recognition People, announced their latest primary healthcare case study where ... turnaround times and to save the practice money. Site ... Challenge: --> ,- Wirral CCG ,- VoicePower ... doctors ,- Wirral CCG ,- VoicePower client since 2013 ...
Breaking Medicine Technology:
Cached News: