HOME >> MEDICINE >> NEWS
Cruciferous vegetables may help some people protect against lung cancer

Eating vegetables from the cabbage family could help individuals with a certain genetic make-up reduce their risk of lung cancer, suggests a research letter in this week's issue of The Lancet.

Whether the consumption of cruciferous vegetables, such as cabbage, broccoli and sprouts, protects against lung cancer is unclear. Some observational studies have shown a protective effect. But a person's genetic status may influence or mask this effect. Cruciferous vegetables are rich in isothiocyanates, which have been shown to have strong chemopreventive properties against lung cancer. Isothiocyanates are eliminated in the body by glutathione-S-transferase enzymes produced by the genes GSTM1 and GSTT1. People who have inactive forms of these genes therefore have higher concentrations of isothiocyanates because of their reduced elimination capacity. Paul Brennan (International Agency for Cancer Research) and colleagues looked at whether the protective effect of cruciferous vegetables was most apparent in these individuals.

The investigators recruited 2141 patients with lung cancer and 2168 age and sex-matched controls from six countries in eastern and central Europe. The researchers gave participants a food questionnaire to fill in and assessed their genetic status from a blood sample. They found that weekly consumption of cruciferous vegetables had a 33% protective effect against lung cancer in people who had an inactive form of the GSTM1 gene. In people who had an inactive GSTT1 gene there was a 37% protective effect, while those with both genes inactivated had a 72% protective effect. The investigators found no protective effect in people with active forms of the genes.

Dr Brennan states: "These data provide strong evidence for a substantial protective effect of cruciferous vegetable consumption on lung cancer."


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
27-Oct-2005


Page: 1

Related medicine news :

1. International symposium on fruit, vegetables headed for Houston
2. Americans still not eating enough fruits and vegetables, according to 2 recent studies
3. 100 percent juices found as beneficial to health as fruits and vegetables
4. National Academies advisory: Native African vegetables
5. Pigments in corn, squash and other vegetables may help protect against age-related vision loss
6. Animal studies suggest vegetables may reduce hardening of arteries
7. Eating more than five portions of fruit & vegetables a day can substantially reduce risk of stroke
8. Higher consumption of some soy products, grains and vegetables linked to reduced risk of lung cancer
9. Warfarin better than aspirin at stroke prevention in elderly people with atrial fibrillation
10. Preventive treatments in elderly people needs rethinking
11. Why do people have sex?

Post Your Comments:
(Date:8/28/2015)... (PRWEB) , ... August 28, 2015 , ... ... abuse, or those who might personally be struggling with chemical dependency, may be ... from Best Drug Rehabilitation, a results-driven holistic treatment center for addiction located in ...
(Date:8/28/2015)... ... 28, 2015 , ... Altima Technologies, Inc., the maker of ... center assets and audio-video devices, recently released Visio Stencils for the following product ... Gen9, EMC VNX Series , Super Micro Computer SuperStorage, Hitachi Data Systems Virtual ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... Veterans Award, honoring military veterans leading in business. Mr. Troy Mizell, Chairman ... , The inaugural Nashville Business Journal's 2015 Veterans Awards will recognize Nashville military ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... loyalty at a low cost. Personalized with practice contact information and logos, Calendars ... Dental offices can also incorporate Calendars into seasonal mailings, thank you and welcome ...
(Date:8/28/2015)... ... August 28, 2015 , ... Mendon, IL, home of the Adams County ... people, all for a good cause. In its second year, the “Music With A ... Best Drug Rehabilitation. The “Mission” of “Music With A Mission” is to raise money ...
Breaking Medicine News(10 mins):Health News:Best Drug Rehabilitation Releases New Video Outlining Patients' Personal Recovery Stories 2Health News:Best Drug Rehabilitation Releases New Video Outlining Patients' Personal Recovery Stories 3Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 2Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 3Health News:MyGenetx Board Member Receives Veterans Award 2Health News:SmartPractice® Introduces 2016 Calendars for Dental Practice Giveaways 2Health News:Best Drug Rehabilitation Sponsors "Music With A Mission" Concert Featuring Avenue Beat 2
(Date:8/28/2015)... , Aug. 28, 2015  Delays in the ... can slow down the decision-making process, resulting in ... absolutely critical for biopharmaceutical companies to develop a ... process for quicker and more meaningful insights. ... Practices, LLC, nearly three-quarters of benchmarked study participants ...
(Date:8/28/2015)... -- According to a new market research ... Type (Protein & Genetic Biomarkers) Profiling Technology (Proteomics, Genomics, ... - Global Forecast to 2020", published by MarketsandMarkets, The ... Million USD by 2020 at a CAGR of 13.9% ... Browse 191 Tables and 38 F ...
(Date:8/28/2015)... 2015 Research and Markets ... "Investigation Report on China,s Bevacizumab Market ,2010-2019" ... under the trade name of Avastin, bevacizumab injection is ... 2010, it was approved by CFDA to treat metastatic ... China all come from Roche and its ...
Breaking Medicine Technology:Expediting the Pharmaceutical Market Research Process for Faster Insights 2Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 2Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 3Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 4Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 5Investigation Report on China's Bevacizumab Market 2015-2019 2
Cached News: