HOME >> MEDICINE >> NEWS
Cruciferous vegetables may help some people protect against lung cancer

Eating vegetables from the cabbage family could help individuals with a certain genetic make-up reduce their risk of lung cancer, suggests a research letter in this week's issue of The Lancet.

Whether the consumption of cruciferous vegetables, such as cabbage, broccoli and sprouts, protects against lung cancer is unclear. Some observational studies have shown a protective effect. But a person's genetic status may influence or mask this effect. Cruciferous vegetables are rich in isothiocyanates, which have been shown to have strong chemopreventive properties against lung cancer. Isothiocyanates are eliminated in the body by glutathione-S-transferase enzymes produced by the genes GSTM1 and GSTT1. People who have inactive forms of these genes therefore have higher concentrations of isothiocyanates because of their reduced elimination capacity. Paul Brennan (International Agency for Cancer Research) and colleagues looked at whether the protective effect of cruciferous vegetables was most apparent in these individuals.

The investigators recruited 2141 patients with lung cancer and 2168 age and sex-matched controls from six countries in eastern and central Europe. The researchers gave participants a food questionnaire to fill in and assessed their genetic status from a blood sample. They found that weekly consumption of cruciferous vegetables had a 33% protective effect against lung cancer in people who had an inactive form of the GSTM1 gene. In people who had an inactive GSTT1 gene there was a 37% protective effect, while those with both genes inactivated had a 72% protective effect. The investigators found no protective effect in people with active forms of the genes.

Dr Brennan states: "These data provide strong evidence for a substantial protective effect of cruciferous vegetable consumption on lung cancer."


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
27-Oct-2005


Page: 1

Related medicine news :

1. International symposium on fruit, vegetables headed for Houston
2. Americans still not eating enough fruits and vegetables, according to 2 recent studies
3. 100 percent juices found as beneficial to health as fruits and vegetables
4. National Academies advisory: Native African vegetables
5. Pigments in corn, squash and other vegetables may help protect against age-related vision loss
6. Animal studies suggest vegetables may reduce hardening of arteries
7. Eating more than five portions of fruit & vegetables a day can substantially reduce risk of stroke
8. Higher consumption of some soy products, grains and vegetables linked to reduced risk of lung cancer
9. Warfarin better than aspirin at stroke prevention in elderly people with atrial fibrillation
10. Preventive treatments in elderly people needs rethinking
11. Why do people have sex?

Post Your Comments:
(Date:8/29/2014)... Village, IL (PRWEB) August 29, 2014 ... Baty, “The Safety Chick” who profiled a handful ... Safe-Listening Earphones from Etymotic Research. This year, many ... list, and Etymotic, an innovator of hearing wellness ... ears. Their ETY•Kids Safe-Listening Earphones, offered in yellow, ...
(Date:8/29/2014)... Mass. (August 29, 2014, 2 PM US Eastern ... is to inject antibodies, commonly produced in animals, ... challenges ranging from safety to difficulties in developing, ... , New research led by Charles Shoemaker, ... and Global Health at the Cummings School of ...
(Date:8/29/2014)... 2014 The microbiology testing sector is ... diagnostics industry; it is also the hugest challenge facing ... the ongoing spread of AIDS – still the world’s ... the upsurge of opportunistic infections (OIs); bioterrorism threat; advancements ... of immunosuppressive medicines. Although for certain infections the etiology ...
(Date:8/29/2014)... News) -- Prostate cancer patients lacking knowledge about the ... lead to worse quality of care and long-term results, ... with a median age of 63. All were newly ... the disease was associated with greater difficulty deciding which ... would be effective, the study found. "For prostate ...
(Date:8/29/2014)... 2014 Edvance360, a leading provider of ... online teaching, as well as 2011 winner and six-time-finalist ... Management System, announced that Brooke Education Services, Northwest Academy, ... Interactive Advertising Bureau of Canada (IAB Canada), StarSVCS, and ... are delighted to welcome each new client to the ...
Breaking Medicine News(10 mins):Health News:The Today Show Features ETY•Kids® Safe-Listening Earphones by Etymotic 2Health News:Mice study shows efficacy of new gene therapy approach for toxin exposures 2Health News:Infectious Disease Testing Universe Examined in New VPG Research Report Available at MarketPublishers.com 2Health News:Infectious Disease Testing Universe Examined in New VPG Research Report Available at MarketPublishers.com 3Health News:Faced With Prostate Cancer, It Helps to Know the Enemy 2Health News:Edvance360 Continues to Experience Growth in Corporate, K-12, Health, and Non-Profit Sectors 2
(Date:8/29/2014)... , Aug. 29, 2014 The clinical and ... be the difference between a product,s success or failure. ... and stratify KOL targets – and then to coordinate ... of strong relationships upon which successful KOL engagement rests. ... companies have identified internal inconsistencies in their KOL management ...
(Date:8/29/2014)... WILSONVILLE, Ore. , Aug. 29, 2014 /PRNewswire-iReach/ ... its Accessory (Axilla) Strap for the SAM Junctional ... SAM Medical Products announced ... a voluntary recall to address a potential issue ... strap used for the Axilla application of the ...
(Date:8/29/2014)...  A Boston Scientific Corporation (NYSE: ... and preliminary long term stricture resolution of benign ... issue of the peer-reviewed journal, Gastroenterology. ... conducted in 11 countries and five continents, and ... (FCSEMS) after extended indwell (i.e., up to 12 ...
Breaking Medicine Technology:Implementing a Strategic Thought Leader Management & Engagement System 2SAM Medical Products Implements Voluntary Recall of its Accessory (Axilla) Strap for the SAM Junctional Tourniquet. 2Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 2Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 3Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 4
Cached News: