CHICAGO, IL (May 17, 2005) This year, more than 145,000 people will be diagnosed with colorectal cancer (CRC). Despite its high incidence, CRC is one of the most preventable and treatable forms of cancer when found early. Studies presented today at Digestive Disease Week 2005 (DDW) explore three novel technologies for colorectal cancer screening that provide innovative techniques that could potentially overcome limitations of existing screening methods. "Colonoscopy is currently the gold standard for detection of colorectal cancer, but is not without its limitations," said Robert Bresalier, M.D., of the University of Texas MD Anderson Cancer Center. "The findings presented today could lead to significant advancements and an overall improvement in the diagnostic efficacy of colon screening."

Onco-LIFE Fluorescence Imaging During Colonoscopy Assists in the Differentiation Of Adenomatous and Hyperplastic Polyps and Improves the Detection Rate Of Dysplastic Lesions in the Colon (Abstract 154)

Researchers are continually looking for new technologies and imaging techniques to enhance the accuracy of CRC screening. In this study by a team of researchers at the University of Toronto, a new fluorescent technology shows significant benefit in improving the diagnostic capability of colonoscopy.

The new technology, "Onco-LIFE" (Light-Induced Fluorescence Endoscopy), uses blue light with combined fluorescence and reflectant cameras to illuminate and obtain real-time color images during colonoscopy procedures. The light reflected in the colon is different when tumors are present, so the color of the images changes to aid in the detection of tumors when used in conjuction with conventional white light imaging.

This study evaluated the device's efficacy in reducing the polyp miss rate and its ability to discriminate between types of tumors. Results suggest that the use of Onco-LIFE as an adjunct to conventional colonoscopy enha
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17-May-2005

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