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Cutting-edge technologies signify a new era for colorectal cancer screening

nces the diagnostic capability of the procedure by increasing the detection of smaller tumors and improves the accuracy of tumor classification at colonoscopy.

A prospective, single-arm, single-center study enrolled patients undergoing colonoscopy for colorectal cancer screening or monitoring. The researchers examined the colon using white light (WL) followed by fluorescence light (FL). Of 285 evaluable biopsies, a total of 123 lesions were found in 44 patients (120 adenomas, two carcinomas and one carcinoid tumor). FL examination identified 19 adenomas (including diminuitive and flat adenomas) that were missed at WL examination, suggesting an increased detection rate of 18.3 percent (19 of 104 adenomas). Accuracy of endoscopic diagnosis for atypical lesions improved from 57 to 83 percent and hyperplastic lesions from 59 to 70 percent with the use of both white and fluorescent light.

"Colonoscopy remains the best way to detect colon cancer. However, we feel that fluorescent technology effectively enhances this standard diagnostic procedure and provides a useful tool for achieving greater accuracy," said Norman Marcon, M.D. of The University of Toronto and senior author of the study. "The results of this trial are promising and warrant further evaluation in larger clinical trials."

Aer-O-Scope: Self-Propelling Self-Navigating Skill-Independent Colonoscopy; a New Era in Screening Colonoscopy (Abstract 90)

The colonoscopy screening procedure has been the subject of debate in the field of gastroenterology due to drawbacks in training, compliance and demand. However, findings presented today show that an innovative technology may bring about a new era in CRC screening. Researchers at the Tel-Aviv Sourasky Medical Center evaluated the safety and efficacy of a self-propelling, self-navigating, skill-independent, miniature colon screening device called an Aer-O-Scope. The device is being developed by GI View Ltd., a st
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17-May-2005


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