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Cutting-edge technologies signify a new era for colorectal cancer screening

d potentially sedationless option.

Unlike conventional endoscopes, the Navigator colonoscope features multiple bendable segments in addition to a physician-controlled distal tip. The System continually monitors the depth and position of the tip, and uses proprietary computer algorithms to build a real-time, three-dimensional map of the patient's colon. The System then directs each of the segments to follow the shape of the colon, as identified by the physician. Because the System is designed to follow the natural shape of the colon, less force is applied to the colon wall. This could potentially eliminate or significantly reduce the incidence of looping, which is responsible for the majority of patient pain in colonoscopy. The System also offers advanced capabilities and features, including the display of a real-time 3-D map of the colon and the ability for physicians to mark the location of polyps on this map.

Researchers conducted initial testing on the scope's force via an inanimate colon model instrumented with four force transducers. Transducers were located at four points: proximal to the simulated anus, the proximal and distal ends of the sigmoid flexure and the splenic flexure. The team measured reductions in average force measurements (pounds) using both a conventional colonoscope (CS) and the study device (SD) and found statistically significant reductions at each of the last three points (CS/SD: 1.2/0.9, 2.5/1.3, 0.7/0.2 and 0.4/0.2).

Secondary studies in animal colons demonstrated the safety of the Navigator Endoscopy System, with no tissue damage or perforations associated with the System.

"Looping is the principle reason that many colonoscopy procedures are painful, time consuming and difficult," said Amir Belson, M.D., president and co-founder of NeoGuide Systems Inc. "We believe that by addressing this, the Navigator Endoscopy System has the potential to significantly increase the number of colonoscopi
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17-May-2005


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