HOME >> MEDICINE >> NEWS
Cystic fibrosis clinical study patients show less lung function decline

Although cystic fibrosis patients in clinical trials had more severe illness, worse lung function, a lower weight level and more respiratory infection than non-participants, their involvement in research studies resulted in less lung function decline over a 7-year period.

The research results appeared in the first issue for January 2006 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Christopher H. Goss, M.D., M.Sc., of the Departments of Medicine and Pediatrics at the University of Washington Medical Center in Seattle, along with three associates, looked at data from 13,041 patients in the Cystic Fibrosis Foundation Registry between 1992 and 1998.

Despite their worse clinical status at the beginning of the study, participants' lung function declined at 1.33 percent per year, as compared with 1.52 percent for non-participants.

Of the 8,375 patients followed for the entire 7-year study period, 2,635 individuals (30.2 percent) were enrolled in at least 1 of 32 Institutional Review Board clinical trials.

"Subjects who were involved in clinical trials were more likely to be older, have commercial health insurance, be white, be colonized with a bacterial infection like Pseudomonas aeruginosa, have worse lung function and have more office visits," said Dr. Goss.

Cystic fibrosis (CF), one of the most common inherited life-shortening illnesses, is characterized by the production of thick, sticky mucus that eventually blocks the small airways, leading to inflammation and infection. Mucus also affects the pancreatic ducts, preventing normal digestion and weight gain. Respiratory failure is the primary cause of early death. CF incidence runs from 1 in 2,000 to 1 in 3,200 live births.

According to the authors, access to better health care through more office visits appeared to be the reason explaining less lung function decline for clinical trial participants.
'"/>

Contact: Suzy Martin
smartin@thoracic.org
212-315-8631
American Thoracic Society
1-Jan-2006


Page: 1 2

Related medicine news :

1. Cystic fibrosis research could benefit from multi-functional sensing tool
2. Early onset of poor bone mineralization revealed in children with cystic fibrosis
3. Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment
4. Study recommends universal newborn screening for cystic fibrosis
5. Stopping inhaled corticosteroid use causes no problems in cystic fibrosis patient users
6. Researchers find effective, cheap treatment for cystic fibrosis lung disease
7. Liver transplants may not be indicated for cystic fibrosis patients with bleeding complication
8. Resonance Health Goup patent for diagnosis of liver fibrosis
9. Little evidence behind bronchodilator therapy for cystic fibrosis
10. Breath test offers hope for early detection of lung-bacteria growth in cystic fibrosis
11. Study proves genetic variations influence cystic fibrosis severity

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2020)... MARY, Fla. (PRWEB) , ... March 27, 2020 , ... ... three-month online educational health conference for people with asthma, their families and caregivers living ... a day between March 27, 2020 and June 30, 2020, and will focus on ...
(Date:3/27/2020)... ... ... global distress and concern about the impact of COVID-19, T1 Payments , a leader ... in an effort to assist hospitality workers whose jobs have been compromised due to ... food service , hotel and other major industries across the United States ...
(Date:3/22/2020)... ... 21, 2020 , ... In partnership with UC Health, Cincy Shirts has created ... and first responders. The title comes from the English translation of “Juncta Juvant”, the ... , Proceeds from the sale of the shirt will benefit the YMCA of ...
(Date:3/22/2020)... ... 2020 , ... “At a time when the public is being told not ... Solutions’ First Stop Health Telemedicine program is a valuable resource to fall ... program, is a valuable tool that can help Americans in their fight to stay ...
(Date:3/20/2020)... ... 2020 , ... My heart goes out to those across our nation and ... loved one recently through similar circumstances - underlying conditions compounded by a virus – ... gamut of negative emotions just like many have: fear, anxiety, uncertainty. In contrast, I ...
Breaking Medicine News(10 mins):
(Date:3/19/2020)... ... March 19, 2020 , ... ... safe and effective as single food immunotherapy, according to research scheduled for presentation ... before it was cancelled due to the situation with coronavirus disease 2019 (COVID-19). ...
(Date:3/16/2020)... ... ... In the wake of the COVID-19 pandemic, Curogram , the leading ... to help the containment of the global disease with its virtual clinic, two-way text ... system. , “Our goal is to minimize exposure and maximize providers’ resources during ...
(Date:3/16/2020)... , ... March 16, 2020 , ... MCH has been ... more than 90 years and maintains a comprehensive database of district and school institution, ... serve U.S. educators, students and communities. The COVID-19 impact map and related data ...
Breaking Medicine Technology:
Cached News: