HOME >> MEDICINE >> NEWS
Daily use of antidepressants associated with increased risk of fracture in older adults

Daily use of the antidepressant medications known as selective serotonin reuptake inhibitors (SSRIs) by adults 50 years and older is associated with a doubled risk of some fractures, according to a report in the January 22, 2007 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Depression affects about 10 percent of primary care patients in the United States, according to background information in the article. The use of SSRIs for the treatment of depressive symptoms is widespread due to the medication's presumed favorable adverse effect profile. Past studies have found the use of these antidepressants to be associated with an increased risk of clinical fragility fracture (fractures due to falling from bed, chair or standing height), but did not reliably examine such factors as falls and bone mineral density, the authors note.

J. Brent Richards, M.D., of McGill University, Montreal, Quebec, and colleagues evaluated 5,008 community-dwelling adults 50 years and older who were followed up for over five years for incident fractures. Researchers examined the relationships between SSRI use, bone mineral density (BMD) and falls. Participants who used the medication at the beginning of the study and at year five were considered to be recurrent users. BMD of the lower spine and hip were measured at the beginning of the study. Patients were then sent a yearly questionnaire to determine if they had experienced clinical fragility fractures and all reported fractures were confirmed radiographically. Other factors such as demographic information, history of falls and medication use were all assessed.

Daily use of SSRIs was reported by 137 participants with an average age of 65.1 years. The researchers found that "daily SSRI use remained associated with a two-fold increased risk of incident clinical fragility fracture even after adjustment for many potential confounding variables." These fractures occurred at the forearm (
'"/>

Contact: Cline Poissant
514-398-6751
JAMA and Archives Journals
22-Jan-2007


Page: 1 2

Related medicine news :

1. Daily weighing and quick action keeps pounds off
2. Daily diet of grapefruit minimizes risk factor for heart disease
3. Studies show antidepressants not linked to birth defects
4. Patients requests for antidepressants can influence physician evaluation of depression
5. Depression, not antidepressants, increases mortality risks in heart failure
6. Selective serotonin reuptake inhibitors antidepressants and risk of violent behavior
7. Carnegie Mellon, Ohio State get grant to study link between antidepressants and suicidality in teens
8. Children and teens taking antidepressants might be more likely to attempt, complete suicide
9. New study suggests antidepressants save lives
10. UCSD/Boston University find antidepressants may affect fetus
11. Stopping antidepressants during pregnancy may lead to symptom recurrence

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... August 31, 2020 , ... Smile Brands Inc., ... in the United States, today announced the grand opening of another affiliated ... Patients will enjoy convenient hours, a comfortable office, and full-service care at the ...
(Date:8/31/2020)... ... August 31, 2020 , ... Dr. Chang has ... with autism and other developmental disabilities, as well as supporting staff in caring ... with autism, school consultation, and staff development. She joined the company in 2015 ...
(Date:8/28/2020)... ... August 28, 2020 , ... WHAT , Hespiro™ ... patients with respiratory conditions, including COVID-19, while reducing the need for scarce mechanical ... captures exhaled gas and scrubs it free of carbon dioxide in a completely ...
(Date:8/28/2020)... ... 2020 , ... Ziegler, a specialty investment bank, is pleased ... Health, a tech-enabled behavioral health and well-being solutions provider. , Synchronous Health, ... intelligence (AI) to increase access and quality of behavioral health services, and Adventist ...
(Date:8/27/2020)... ... 27, 2020 , ... Evolution Labs announced today that Florida ... with Suite360:Mental Health and Prevention, a program developed to help students navigate a ... , Florida schools and districts must provide their students with preventative lessons after ...
Breaking Medicine News(10 mins):
(Date:9/2/2020)... , ... September 02, 2020 ... ... Fight Against Covid-19 , Advanced Penetration Technology, LLC, (APT) a Texas- and ... patients utilizing non-prescription, Over The Counter (OTC) products, was today provided results ...
(Date:9/1/2020)... ... 2020 , ... While coronavirus cases continue to increase across the country, blood ... remain closed. Because about 80% of blood donations are made at drives hosted by ... blood drive hosts to ensure blood products are readily available for patients. , ...
(Date:8/31/2020)... ... 2020 , ... Continuing on its rapid national expansion - ... deodorization provider - is proud to announce it has opened doors in Phoenix, ... residents throughout the area. , Germinator provides a 100% safe and non-toxic sanitizing ...
Breaking Medicine Technology:
Cached News: