HOME >> MEDICINE >> NEWS
Deep brain stimulation in Parkinson disease reduces uncontrolled movements

CHICAGO Deep brain stimulation of two different areas of the brain appears to improve problems with uncontrolled movements (dyskinesia) in patients with Parkinson disease (PD), according to an article in the April issue of Archives of Neurology, one of the JAMA/Archives journals.

Deep brain stimulation with electrical impulses delivered to structures deep within the brain is being intensively investigated for the management of advanced Parkinson disease, according to background information in the article. Although a number of studies have shown that stimulation of two different areas of the brain, the globus pallidus interna (GPi) and the subthalmic nucleus (STN), can be achieved safely and effectively, STN has been thought to be the preferred target. At the same time, the authors note, there does seem to be some evidence that the STN is more vulnerable during surgery and that STN patients may have more postoperative problems.

Valerie C. Anderson, Ph.D., of the Oregon Health and Science University, Portland, and colleagues compared 23 patients with Parkinson disease and problems with medication-induced uncontrolled movement who were randomly assigned to implantation of deep brain stimulators in either the GPi or the STN areas of the brain. Patients' Parkinson symptoms were evaluated with and without medication using a standard rating scale at three, six and 12 months after surgery.

"Off-medication Unified Parkinson's Disease Rating Scale motor scores were improved after 12 months of both GPi and STN stimulation (39 vs 48 percent)," the authors write. "Bradykinesia [extremely slow movement] tended to improve more with STN than GPi stimulation. No improvement in on-medication function was observed in either group. Levodopa [Parkinson medication] dose was reduced by 38 percent in STN stimulation patients compared with three percent in GPi stimulation patients. Dyskinesia was reduced by stimulation at both GPi and STN ( 89 v 62 percent). Cogn
'"/>

Contact: Jonathan Modie
503-494-8231
JAMA and Archives Journals
11-Apr-2005


Page: 1 2

Related medicine news :

1. Draining away brains toxic protein to stop Alzheimers
2. New research discovers independent brain networks control human walking
3. ADHD appears to be associated with depressed dopamine activity in the brain
4. First of its kind report on how children with brain tumors perform at school
5. Chemical in brain acts like a fuel gauge
6. Case study: cross-cultural bioethics training program helps fight African brain drain
7. Paying taxes, according to the brain, can bring satisfaction
8. Childrens brain responses predict impact of sleep loss on attention
9. Old memory traces in brain may trigger chronic pain
10. Stanford researchers track human stem cells transplanted into rat brain
11. Drug shows activity against brain metastases

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/22/2019)... (PRWEB) , ... May 22, 2019 , ... ... Avante Ultrasound, announced the implementation of a common management structure that aligns both ... Solutions’ location in Ontario, Calif. has become Avante Ultrasound’s west coast operations center, ...
(Date:5/22/2019)... ... May 22, 2019 , ... Medicaid helps ... mothers, according to a new report by the Georgetown University Center for Children ... uninsured rates for women of childbearing age and larger reductions in maternal deaths ...
(Date:5/22/2019)... ... 22, 2019 , ... EY today announced that Bob Arnesen, ... the Entrepreneur Of The Year® 2019 Award in the New England region. Widely ... program recognizes entrepreneurs and leaders of high-growth companies who are excelling in areas ...
(Date:5/22/2019)... ... May 22, 2019 , ... Care to Care took ... the economic impact of misdiagnosis of imaging procedures. According to Lisa Woods, Senior ... of the diagnostic imaging their employees were receiving, including CT scans and MRI ...
(Date:5/22/2019)... ... May 22, 2019 , ... ... health observance, National Lifestyle Medicine Week, to take place May 28 to June ... evidence-based therapeutic approaches of Lifestyle Medicine: a whole food, plant-predominant dietary lifestyle, regular ...
Breaking Medicine News(10 mins):
(Date:5/23/2019)... ... 2019 , ... Educators at public K-12 schools are running out of time ... http://www.calcasmusicartsgrant.com . The entry deadline is June 30, 2019, with grants awarded in September. ... their arts and performance programs could use more funding,” said California Casualty ...
(Date:5/22/2019)... ... 2019 , ... Ziegler, a specialty investment bank with a ... the $22,375,000 Series 2019 for Trevecca Nazarene University. The Series 2019 tax-exempt bonds ... of Nashville and Davidson County, Tennessee. Proceeds from the 2019 Bonds will be ...
(Date:5/22/2019)... ... May 22, 2019 , ... ... two new products, Ultra-Relief and Ultra-Relax, that are designed to increase the benefits ... not contain CBD, but instead contain terpenes and other natural ingredients that have ...
Breaking Medicine Technology:
Cached News: