HOME >> MEDICINE >> NEWS
Delaying medication for infrequent seizures may be the best option

Giving individuals with single or infrequent seizures immediate treatment does not reduce their risk of seizure recurrence in the long-term, suggests a randomised trial published in this week's issue of THE LANCET. The authors also found that delaying medication did not increase the risk of chronic epilepsy in this group of people.

The risks and benefits of starting or withholding antiepileptic drug treatment in patients with few or infrequent seizures are unclear.

Between 1993 and 2000, David Chadwick (University of Liverpool, UK) and colleagues, recruited around 1400 patients with single or infrequent seizures from centres in the UK and around the world. Half the individuals were assigned to immediate treatment with antiepileptic drugs and half were assigned to deferred treatment, where they received no drug until they and their clinician agreed treatment was necessary. Immediate treatment reduced short-term seizure recurrence but had no effect on long-term outcomes. More patients in the immediate treatment group than in the deferred group experienced adverse effects that were probably treatment related. There was no difference in quality of life between the two groups.

Professor Chadwick concludes: "We have sought to quantify precisely benefits in terms of seizure control, to improve the quality of information available to support clinicians and patients in making decisions about treatment optionsWe have shown that a policy of immediate treatment with antiepileptic drugs, mainly with carbamazepine or valproate, reduces the occurrence of seizures in the next 12 years, but does not modify rates of long-term remission after a first or after several seizures. At 2 years, the benefits of improved seizure control with immediate treatment seem to be balanced by the unwanted effects of drug treatment and there is no improvement in measures of quality of life."

In an accompanying comment Samuel Berkovic (University of Melborne, Australia)
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
9-Jun-2005


Page: 1 2

Related medicine news :

1. Delaying surgery is a safe, acceptable option for some men with hernia
2. Delaying surgery for hernia repair a safe option
3. Delaying radiation for prostate cancer does not affect outcome
4. Adding medication improves recovery for elderly with depression, says Pitt School of Medicine study
5. Heart failure medication does not improve survival, compared to more widely used medication
6. Commonly used pain medications do not prevent Alzheimers disease
7. Standard long-acting insulin as good as newer medications
8. MS patients not receiving medications to slow disease progression, research shows
9. Study sheds light on medication treatment options for bipolar disorder
10. Landmark schizophrenia treatment study reveals that medication alone is not always effective
11. Cost control measures limit patient and physician choice in psychotropic medications

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2018)... ... ... SignatureCare Emergency Center is looking to award their 2018 Fall Scholarship. The $1000 ... your applications in now as the deadline is approaching fast. (July 31) , SignatureCare ... student at Texas Southern University. Wu was inspired to go into the medical field ...
(Date:8/31/2018)... ... 31, 2018 , ... MedMark Treatment Centers Kentwood, a BayMark ... from 1:00-3:00 pm. MedMark invites the community to explore the world ... meet our staff and learn more about medication-assisted treatment services. MedMark Kentwood can ...
(Date:8/31/2018)... (PRWEB) , ... August 31, 2018 , ... Nitro Circus ... SeaLegs at the Beach – an action sports gathering to celebrate the life of ... The event raised money for Erik’s wife, Annika and their two small children, Oskar ...
(Date:8/31/2018)... ... 2018 , ... ZPower, the world’s only developer of rechargeable, ... Information Officer. Arneja previously served as Director of Information Systems and in his ... scale, and innovate the business. , Prior to joining ZPower, Arneja gained ...
(Date:8/29/2018)... ... August 29, 2018 , ... ... socialize or communicate with others. Physically, it is not possible to identify people ... problems may be challenged. People with autism may need assistance in developing skills, ...
Breaking Medicine News(10 mins):
(Date:9/1/2018)... ... September 01, 2018 , ... Dr. Payam Bostani is now offering Periodontal ... he has been offering patients for twenty years at his Burbank offices. “My ... are likely to need under a single roof. Periodontics is a crucial specialty because ...
(Date:8/31/2018)... , ... August 31, 2018 , ... ... Government to acquire, such as medications for cancer, mental health and required blood ... used to treat Respiratory Distress Syndroms (RDS) in premature babies and can be ...
(Date:8/31/2018)... ... 31, 2018 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... Tabernacles topics and events. He says polls show the world is begging for answers ... , Yisrayl says The House of Yahweh has been asked to teach solutions ...
Breaking Medicine Technology:
Cached News: