HOME >> MEDICINE >> NEWS
Derivatives of cannabis for anti-cancer treatment win Kaye Award for Hebrew University student

Derivatives of the cannabis plant (hashish) have been shown by a Hebrew University of Jerusalem Ph.D. student to be effective in arresting cancerous growths in laboratory and animal tests.

For her work, Natalya Kogan was one of the winners of a Kaye Innovation Award, presented today during the 68th meeting of the Hebrew University Board of governors.

Working under the supervision of Prof. Raphael Mechoulam at the Hebrew University School of Pharmacy (in collaboration with Prof. Michael Schlesinger at the Hebrew University-Hadassah Medical School and Prof. Ester Priel at Ben-Gurion University of the Negev), Kogan has developed new compounds known as quinonoid cannabinoids that parallel in their activity a group of anti-cancer drugs, the best known of which is daunomycin.

However, while daunomycin is toxic to the heart, Kogan, with Dr. Ronen Beeri and Dr. Gergana Marincheva of Hadassah University Hospital, Ein Kerem, found that the quinonoid cannabinoids are much less cardiotoxic. The development of quinonoid compounds that display anticancer activity, but are less toxic, is a major therapeutic goal. At present, Kogan is continuing to investigate the mechanism of action of these promising compounds.

All of the compounds synthesized by Kogan inhibited cancer cell growth in cell culture, and one of them was found to markedly reduce the volume of tumors in animal studies The cannabinoid quinones were found to act through a rather unique pathway of cancer cell destruction -- by specific inhibition of topoisomerase II, an enzyme that participates in cell replication. Most of the known anti-cancer drugs are less selective, acting by numerous mechanisms.

Additionally, the most active compound in the series developed by Kogan, as well as some other cannabinoids, were found by Kogan and Prof. Ruth Galilli of the Hebrew University to have anti-angiogenic properties. Angiogenesis, the process of new blood vessel formation, is cr
'"/>

Contact: Jerry Barach
972-2-588-2904
The Hebrew University of Jerusalem
6-Jun-2005


Page: 1 2

Related medicine news :

1. Smokeless cannabis delivery device efficient and less toxic
2. Imaging technique sheds new light on the composition of the brain of moderate cannabis users
3. New antidepressant drug increases brains own cannabis
4. New algorithm matches any tumor cells to best possible anti-cancer treatments
5. UCLA researchers develop new nanomaterials to deliver anti-cancer drugs to cells
6. Vorinostat shows anti-cancer activity in recurrent gliomas
7. Research says boiling broccoli ruins its anti-cancer properties
8. Northwestern chemists develop new method for synthesizing anti-cancer flavonoids
9. Mistletoe is not an anti-cancer drug, say doctors
10. Erectile dysfunction drugs heighten natural anti-cancer activity
11. New litmus test could aid discovery of anti-cancer drugs

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... NY (PRWEB) , ... December 08, 2016 , ... ... is pleased to announce that “Natural Language Processing–Enabled and Conventional Data Capture Methods ... in JMIR Medical Informatics . , Results of the comparative usability study ...
(Date:12/8/2016)... ... 2016 , ... David J. Dykeman , Ginger Pigott , and ... speak at DeviceTalks West, Dec. 12, 2016, at the Fairmont Newport Beach in California. ... firm’s global Life Sciences & Medical Technology Group have been featured speakers at every ...
(Date:12/8/2016)... ... , ... STATEN ISLAND, N.Y., Nov. 24, 2016 — ... standards of trauma, maternity, cancer and chronic obstructive pulmonary disease (COPD) services from ... Messina. , Among the recognitions, the American College of Surgeons' (ACS) named the ...
(Date:12/8/2016)... ... 08, 2016 , ... Vida Health, the digital health platform that ... Canvas Ventures . Other investors include Nokia Growth Partners (NGP) and returning investor ... more consumers who are managing chronic conditions or simply want to improve ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... Coppin Insurance ... owners and families in and around the Cape Coral area, is embarking on a ... Food Bank of Southwest Florida. , The Harry Chapin Food Bank of Southwest Florida ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... SAN DIEGO , Dec. 8, 2016 /PRNewswire/ ... dedicated to improving cancer patient care from diagnosis ... the company,s recently completed Phase 1b study in ... at the San Antonio Breast Cancer Symposium. ... Cancer Center at UC San Diego Health, delivered ...
(Date:12/8/2016)... , Dec. 8, 2016  Hanson Research, an ... dissolution testing and diffusion testing instruments for the ... by Teledyne Instruments, Inc. ("Teledyne"). The move is ... of precision testing instruments, as well as expand ... of new products and services. Logo - ...
(Date:12/8/2016)... , Dec. 8, 2016  Haemonetics Corporation (NYSE: ... DMS (Donor Management System), an innovative software suite designed to ... The launch of NextGen DMS 4 improves core ... reducing the cost per liter of plasma collected, enhancing quality ... plasma center operations. ...
Breaking Medicine Technology:
Cached News: