HOME >> MEDICINE >> NEWS
Diabetic hearts make unhealthy switch to high-fat diet

ments using diabetic animals. But this is the first time researchers have confirmed that burning of fatty acids in the heart muscle is increased in humans with diabetes. In this study, 11 healthy, non-diabetic people were compared to 11 otherwise healthy people with type 1 diabetes. The researchers found that the diabetic patients had much higher levels of fats in their blood and had an increased uptake of fatty acids into heart muscle cells.

The cells of diabetic hearts not only absorbed more fat, they also burned a higher percentage of the fats they took in. As a result, diabetic heart muscle used about half as much glucose and four times more fat for energy than the hearts of non-diabetics.

The researchers are now engaged in a larger study of heart muscle metabolism in type 2 diabetics. Patients in the study are divided into two groups with one group receiving standard therapies to normalize blood glucose levels and the other group receiving additional therapies designed to decrease the amount of fat in the blood. The study is still accruing patients, and people with type 2 diabetes who would like to participate can call 314-362-8608.

If the increased blood-fat levels are confirmed to be responsible for the dysfunctional metabolism of diabetic heart muscle, reducing fat levels may become an important way to decrease illness and death from cardiovascular disease in diabetics, according to the authors.

"We believe it's not enough to control blood glucose in diabetes," Gropler says. "You also have to target fat delivery to the heart. If you decrease the fat delivery through a combination of diet, exercise and drugs, you'll improve the heart's ability to use other energy sources, which will improve heart health."


'"/>

Contact: Gwen Ericson
ericsong@wustl.edu
314-286-0141
Washington University School of Medicine
3-Feb-2006


Page: 1 2

Related medicine news :

1. Diabetics see dramatic increase in lower limb amputations
2. Diabetic patients often overestimate healthy body weight
3. Diabetics who control blood sugar today are more likely to have healthy feet and nerves tomorrow
4. Diabetic blacks have less coronary artery disease than diabetic whites
5. Diabetics with high blood pressure benefit from water pills
6. Diabetic retinopathy occurs in pre-diabetes
7. Making old hearts young again
8. Does endurance exercise promote life-threatening changes in athletes hearts?
9. Overweight and obesity enlarges teenagers hearts
10. Older donor hearts just as good, University of Alberta study shows
11. Jefferson scientists test new device for fixing holes in hearts of young stroke patients

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Diabetic hearts make unhealthy switch high fat diet

(Date:4/18/2014)... turns 160 years of neuroanatomy on its head. , ... essential for the fast transmission of impulses along the ... thought, according to a new work lead by Professor ... and the University,s Department of Stem Cell and Regenerative ... Department of Molecular and Cellular Biology. , "Myelin is ...
(Date:4/18/2014)... psychologists have made a brain-related discovery that could ... , This discovery opens up the possibility that ... a specific brain activity that the researchers have ... Journal of Neuroscience has just published ... an associate professor of psychology and his doctoral ...
(Date:4/17/2014)... in benign prostate tissue was associated with high-grade, ... found even in those with low prostate-specific antigen ... Cancer Epidemiology, Biomarkers & Prevention , a ... , An analysis of prostate tissue biopsies collected ... the Prostate Cancer Prevention Trial (PCPT) found that ...
(Date:4/17/2014)... One of the most popular vaccine brands for children ... may be overlooking some cost factors when choosing vaccines, ... expensive option, according to a new study by University ... administer can be driven by numerous factors," says Sheldon ... professor of computer science and of mathematics at the ...
(Date:4/17/2014)... AURORA, Colo. (April 17, 2014) Two recent ... Medicine researcher and colleagues may help scientists develop ... virus, Yellow fever, Japanese encephalitis and other disease-causing ... of biochemistry and molecular genetics at the School ... the Howard Hughes Medical Institute, and colleagues recently ...
Breaking Medicine News(10 mins):Health News:Finding turns neuroanatomy on its head 2Health News:Finding turns neuroanatomy on its head 3Health News:Scientists discover brain's anti-distraction system 2Health News:Chronic inflammation may be linked to aggressive prostate cancer 2Health News:Chronic inflammation may be linked to aggressive prostate cancer 3Health News:Study recalculates costs of combination vaccines 2Health News:CU researchers discover target for treating dengue fever 2
(Date:1/15/2014)... is very pleased to announce the appointment of Mr. ... Mark was promoted from his current role of Chief Operating ... in Massachusetts , Mississippi ... 2012 with 20+ years of broad-based operations, sales, engineering and ...
(Date:1/15/2014)... Jan. 15, 2014  According to Millennium Research Group ... intelligence, the United States ... markets will expand moderately through 2022, with embolization ... particular, increasing interest in drug-eluting beads (DEBs) and ...
(Date:1/15/2014)... Jan. 15, 2014 Reportlinker.com announces that ... in its catalogue: ... Delivery Systems -- Focus on End Users ... STUDY OBJECTIVES A drug delivery ...
Breaking Medicine Technology:Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 2US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 16Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 18
Cached News: