HOME >> MEDICINE >> NEWS
Diabetic hearts make unhealthy switch to high-fat diet

ments using diabetic animals. But this is the first time researchers have confirmed that burning of fatty acids in the heart muscle is increased in humans with diabetes. In this study, 11 healthy, non-diabetic people were compared to 11 otherwise healthy people with type 1 diabetes. The researchers found that the diabetic patients had much higher levels of fats in their blood and had an increased uptake of fatty acids into heart muscle cells.

The cells of diabetic hearts not only absorbed more fat, they also burned a higher percentage of the fats they took in. As a result, diabetic heart muscle used about half as much glucose and four times more fat for energy than the hearts of non-diabetics.

The researchers are now engaged in a larger study of heart muscle metabolism in type 2 diabetics. Patients in the study are divided into two groups with one group receiving standard therapies to normalize blood glucose levels and the other group receiving additional therapies designed to decrease the amount of fat in the blood. The study is still accruing patients, and people with type 2 diabetes who would like to participate can call 314-362-8608.

If the increased blood-fat levels are confirmed to be responsible for the dysfunctional metabolism of diabetic heart muscle, reducing fat levels may become an important way to decrease illness and death from cardiovascular disease in diabetics, according to the authors.

"We believe it's not enough to control blood glucose in diabetes," Gropler says. "You also have to target fat delivery to the heart. If you decrease the fat delivery through a combination of diet, exercise and drugs, you'll improve the heart's ability to use other energy sources, which will improve heart health."


'"/>

Contact: Gwen Ericson
ericsong@wustl.edu
314-286-0141
Washington University School of Medicine
3-Feb-2006


Page: 1 2

Related medicine news :

1. Diabetics see dramatic increase in lower limb amputations
2. Diabetic patients often overestimate healthy body weight
3. Diabetics who control blood sugar today are more likely to have healthy feet and nerves tomorrow
4. Diabetic blacks have less coronary artery disease than diabetic whites
5. Diabetics with high blood pressure benefit from water pills
6. Diabetic retinopathy occurs in pre-diabetes
7. Making old hearts young again
8. Does endurance exercise promote life-threatening changes in athletes hearts?
9. Overweight and obesity enlarges teenagers hearts
10. Older donor hearts just as good, University of Alberta study shows
11. Jefferson scientists test new device for fixing holes in hearts of young stroke patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/20/2017)... ... 2017 , ... Adolfson & Peterson Construction (AP) continues to ... a leader in healthcare construction, AP has successfully built several well-known medical facilities ... with Josh now on board. , Josh brings over nine years of ...
(Date:7/20/2017)... ... July 19, 2017 , ... A July 7th article ... worsen, varicose veins in some patients, according to medical experts. Washington State medical ... like excessive sitting or standing, or regularly nicking yourself while shaving your legs, ...
(Date:7/20/2017)... (PRWEB) , ... July 20, 2017 , ... “Lucky the Buffalo and Her Adventures”: a ... of published author, Edward Bieniek. Edward Steven Bieniek Jr. was born in Toledo, Ohio. ... of Toledo at com tech. He is married to a brilliant woman with a ...
(Date:7/18/2017)... ... July 18, 2017 , ... Cognition Corporation ... announced two more sessions of its “From the Helm” Webinar Series. , ... by David Cronin, Cognition’s CEO, the half-hour public webinars will take an in-depth ...
(Date:7/18/2017)... ... ... international clinical trial, led in part by a UC Davis School of Medicine expert, have ... a subgroup of patients. , In a paper just published online in the journal ... countries describe the clinical benefit of using the drug ataluren for a certain group of ...
Breaking Medicine News(10 mins):
(Date:7/10/2017)... S.C. , July 10, 2017  BDI ... purchasing and patient support services organization serving specialty ... today the launch of four significant, value-added member ... market insights, better manage reimbursement and improve access ... and factor therapies. ...
(Date:7/6/2017)... , July 6, 2017 ThriveRx, the nutrition division of Diplomat ... families to thrive on nutrition support. To celebrate its anniversary, ... site has a fresh new look with improved organization to create the ... ... "We,ve ...
(Date:7/5/2017)... 5, 2017 Pace Analytical, a company of over 2,000 employees and ... have acquired ESC Lab Sciences, further solidifying their position as the top American ... . ... and CEO of Pace Analytical ... out of Mt Juliet, TN , enhances Pace Analytical,s capability ...
Breaking Medicine Technology:
Cached News: