While most women may experience mild emotional or physical premenstrual symptoms, as many as eight to 20 percent of women experience symptoms severe enough to meet the definition of premenstrual syndrome, characterized by moderate to severe symptoms that substantially interfere with normal life activities and interpersonal relationships, according to background information in the article. Previous studies have suggested that calcium supplements and vitamin D, a hormone that regulates the absorption of calcium, may reduce premenstrual occurrence and severity.

Elizabeth R. Bertone-Johnson, Sc.D., of the University of Massachusetts, Amherst, and colleagues compared the diets and supplement use of 1,057 women aged 27 to 44 years who reported developing PMS over the course of 10 years to 1,968 women who reported no diagnosis of PMS or no or minimal premenstrual symptoms in the same time period. The women, who participated in the Nurses Health Study (NHS), all reported no PMS in 1991, at the beginning of the study period. Their intake of calcium and vitamin D from diet and/or supplements was calculated from food frequency and standard NHS questionnaires administered in 1991, 1995 and 1999.

"We observed a significantly lower risk of developing PMS in women with high intakes of vitamin D and calcium from food sources, equivalent to about four servings per day of skim or low-fat milk, fortified orange juice or low-fat dairy foods such as yogurt," the authors write. "These dietary intakes correspond to approximately 1,200 mg. of calcium and 400 IU of vitamin D from food sources. While previous studies have observed the benefits of calcium supplements for treating PMS, this is the first, to our knowledge, to suggest that calcium and vit
'"/>

Contact: Ed Blaguszewski
413-545-2986
JAMA and Archives Journals
13-Jun-2005