HOME >> MEDICINE >> NEWS
Disposable sensor uses DNA to detect hazardous uranium ions

CHAMPAIGN, Ill. Researchers at the University of Illinois at Urbana-Champaign have developed a simple, disposable sensor for detecting hazardous uranium ions, with sensitivity that rivals the performance of much more sophisticated laboratory instruments.

The sensor provides a fast, on-site test for assessing uranium contamination in the environment, and the effectiveness of remediation strategies, said Yi Lu, a chemistry professor at Illinois and senior author of a paper accepted for publication in the Proceedings of the National Academy of Sciences, and posted on its Web site.

A unique feature of our uranium sensor is that it contains a small piece of DNA, the same basic building blocks of our genes, said Lu, who also is a researcher at the universitys Beckman Institute for Advanced Science and Technology, and at the Center of Advanced Materials for the Purification of Water with Systems. Our sensor combines the high metal ion selectivity of catalytic DNA with the high sensitivity of fluorescence detection.

While most DNA is double stranded, the catalytic DNA Lus research group uses has a single strand region that can wrap around like a protein. In that single strand, the researchers fashion a specific binding site a kind of pocket that can only accommodate the metal ion of choice.

In this case, the researchers chose to detect uranyl, the most soluble species of uranium ion and the one that poses the greatest threat to human life.

To search for the unique sequence of DNA that could distinguish uranyl from other metal ions, the researchers used a combinatorial approach called in vitro selection. Simple and cost-effective, the selection process can sample a very large pool of DNA (up to 1,000 trillion molecules), amplify the desired sequence by the polymerase chain reaction, and introduce mutations to improve performance.

Lu, with collaborators at Illinois, the Construction Engineering Research Laboratory, Oregon S
'"/>

Contact: James E. Kloeppel, Physical Sciences Editor
kloeppel@uiuc.edu
217-244-1073
University of Illinois at Urbana-Champaign
14-Feb-2007


Page: 1 2

Related medicine news :

1. Disposable catheter breakthrough, a world first
2. Extreme weather monitoring boosted by space sensor
3. Color sensor breath test can detect lung cancer
4. In-home sensors spot dementia signs in elderly
5. Smell of success for nanobiosensors
6. New engineering center to transform sensor technology
7. Portable cocaine sensor developed at UC Santa Barbara
8. New sensor to provide early warning of oxygen loss to unborn children
9. Early experience may shape our sensory perceptions
10. Biosensor reveals new information about suspected cause of Alzheimers disease
11. Mental health following stroke, spinal cord injury; sensory evaluation tools

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... , ... Apple Rehab Shelton Lakes , which specializes in the delivery ... as part of a disaster drill on October 3rd. , Apple Rehab participated with ... Manager, as well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). ...
(Date:10/13/2017)... ... , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many ... event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids ... of all ages; it is a non-competitive, non-timed event, which is all about having ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the Mission ... lost souls in the Philippines. “The Journey: From the Mountains to the Mission Field” ... the Bible. She has taught all ages and currently teaches a class of ladies ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest ... its plans to open a flagship location in Covington, LA at 401 N. U.S. ... Go store next to Office Depot in the Holiday Square shopping center. Its location ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... 11, 2017  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), ... in Las Piedras, Puerto Rico , ... Following a ... sustained minor structural damage, temporary loss of power and ... been completed, manufacturing operations have resumed, and the company ...
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare ... CPR training aide "cprCUBE" on Kickstarter. The device will ... during cardiac arrests with better efficiency compared to the ... offers real-time feedback on efficacy of the compression for ... campaign has a goal to raise $5,000. ...
(Date:10/2/2017)... , Oct. 2, 2017  AllianceRx Walgreens Prime, the ... by Walgreens and pharmacy benefit manager Prime Therapeutics LLC ... brand, which included the unveiling of new signage at ... as well as at a few other company-owned facilities ... brand to patients, some of whom will begin to ...
Breaking Medicine Technology:
Cached News: