HOME >> MEDICINE >> NEWS
Doctors conclude temsirolimus is effective new treatment for advanced renal cell carcinoma

The results of a phase III, randomized clinical study involving patients with advanced renal cell carcinoma and poor prognostic features show temsirolimus improved overall survival when compared to the current treatment for this stage of disease. The study, led by Gary R. Hudes, M.D., director of the Genitourinary Malignancies Program at Fox Chase Cancer Center, is published in the May 31 issue of the New England Journal of Medicine.

A total of 626 patients with renal cell carcinoma (RCC) were enrolled in the study and received one of three treatments a new drug called temsirolimus, an older drug called interferon, or both the new and old drugs together. The patients who received temsirolimus alone survived longer than those who received interferon, the usual or standard treatment for this disease.

"This is the first study to show that a new drug can improve overall survival for patients with metastatic renal cell cancer," said Hudes.

Patients who received both drugs - temsirolimus and interferon - did not appear to live longer than those given interferon. Hudes said this finding could be explained by the lower dose of temsirolimus given to patients who received the combination treatment.

Renal cell carcinoma (RCC) is the most common type of kidney cancer. Approximately 90 percent of the 51,190 new cases of kidney cancer diagnosed this year will be RCC. Although many patients with kidney cancer are cured by surgery that removes the tumor, approximately 35 percent of patients will experience a recurrence of their cancer or will have spread (metastasis) of their cancer to other organs.

"For these patients, the goal of treatment is to prevent further spread and growth of the cancer, and ideally, to reduce that amount of cancer," Hudes said. "Until recently, physicians lacked effective drugs to control the disease."

In the current study, the greatest increase in median survival was observed i
'"/>

Contact: Karen Mallet
karen.mallet@fccc.edu
215-728-2700
Fox Chase Cancer Center
30-May-2007


Page: 1 2

Related medicine news :

1. Doctors have key role in preventing and detecting child neglect and abuse
2. Doctors, engineers develop new wireless system to detect esophageal reflux
3. Doctors ill equipped to confront parent smoking
4. Doctors test effort that helps people understand health risk information
5. Doctors neglect insomnia in older patients
6. Doctors extended duration work shifts are associated with medical errors and adverse events
7. Doctors working overseas face having licenses removed
8. Doctors must debate hospital closures
9. Doctors cut repeat LASIK visits dramatically
10. Doctors warn: Do not rely only on what young athletes say when managing concussions
11. Doctors know best when it comes to treating chronic coronary artery disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... ... largest non-profit organization devoted exclusively to funding innovative lymphoma research and serving the ... services – today announced the 10th Anniversary of Blood Cancer Awareness Month (BCAM) ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... ... of innovative higher-learning opportunities through high-quality, career-relevant, and affordable online education – is ... Psychology . , Among the first of its kind in the nation, ...
(Date:8/31/2020)... ... 2020 , ... Dr. Chang has over 20 years of ... developmental disabilities, as well as supporting staff in caring for patients and families. ... and staff development. She joined the company in 2015 as Chief of Clinical ...
(Date:8/28/2020)... ... August 28, 2020 , ... ... to a customized Lighthouse Health & Wellness mobile app and web-portal. NCPCV received ... Motorola Solutions Foundation awards grants each year to organizations, such as Destination Imagination, ...
(Date:8/27/2020)... (PRWEB) , ... August 27, 2020 , ... ... has joined the Walk-in Dermatology team in its Greenvale, New York location. ... Nail and Skin Care Institute. She is certified in chemical peels, microdermabrasion, Hydrafacial ...
Breaking Medicine News(10 mins):
(Date:8/31/2020)... ... ... you live in New York City you will always pay more for these two things: ... supply and demand, but are plastic surgeons in New York worth the premium prices that ... make the four-hour trip to have expert aesthetic treatments by some of the best doctors ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... advisory guide, has named Cloudticity a Gold winner in the 15th Annual 2020 ... peer recogniti o ns from Network Products Guide honoring achievements of ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Dr. ... reproductive and endoscopic surgeon and serves as a clinical professor in the Department of ... of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical ...
Breaking Medicine Technology:
Cached News: