HOME >> MEDICINE >> NEWS
Doctors conclude temsirolimus is effective new treatment for advanced renal cell carcinoma

The results of a phase III, randomized clinical study involving patients with advanced renal cell carcinoma and poor prognostic features show temsirolimus improved overall survival when compared to the current treatment for this stage of disease. The study, led by Gary R. Hudes, M.D., director of the Genitourinary Malignancies Program at Fox Chase Cancer Center, is published in the May 31 issue of the New England Journal of Medicine.

A total of 626 patients with renal cell carcinoma (RCC) were enrolled in the study and received one of three treatments a new drug called temsirolimus, an older drug called interferon, or both the new and old drugs together. The patients who received temsirolimus alone survived longer than those who received interferon, the usual or standard treatment for this disease.

"This is the first study to show that a new drug can improve overall survival for patients with metastatic renal cell cancer," said Hudes.

Patients who received both drugs - temsirolimus and interferon - did not appear to live longer than those given interferon. Hudes said this finding could be explained by the lower dose of temsirolimus given to patients who received the combination treatment.

Renal cell carcinoma (RCC) is the most common type of kidney cancer. Approximately 90 percent of the 51,190 new cases of kidney cancer diagnosed this year will be RCC. Although many patients with kidney cancer are cured by surgery that removes the tumor, approximately 35 percent of patients will experience a recurrence of their cancer or will have spread (metastasis) of their cancer to other organs.

"For these patients, the goal of treatment is to prevent further spread and growth of the cancer, and ideally, to reduce that amount of cancer," Hudes said. "Until recently, physicians lacked effective drugs to control the disease."

In the current study, the greatest increase in median survival was observed i
'"/>

Contact: Karen Mallet
karen.mallet@fccc.edu
215-728-2700
Fox Chase Cancer Center
30-May-2007


Page: 1 2

Related medicine news :

1. Doctors have key role in preventing and detecting child neglect and abuse
2. Doctors, engineers develop new wireless system to detect esophageal reflux
3. Doctors ill equipped to confront parent smoking
4. Doctors test effort that helps people understand health risk information
5. Doctors neglect insomnia in older patients
6. Doctors extended duration work shifts are associated with medical errors and adverse events
7. Doctors working overseas face having licenses removed
8. Doctors must debate hospital closures
9. Doctors cut repeat LASIK visits dramatically
10. Doctors warn: Do not rely only on what young athletes say when managing concussions
11. Doctors know best when it comes to treating chronic coronary artery disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2020)... ... February 13, 2020 , ... Charles ... Assisted Living in Phoenix, AZ announced today his re-election as the President of ... Living Facility Managers (NCIA). , As President of the State Board, Villafranca ...
(Date:2/11/2020)... ... 2020 , ... Soterius, Inc., a global provider of cutting-edge ... new, significantly larger business premises in Lawrenceville, NJ. The move supports the requirements ... digital technology platforms. , “As our customer base and offerings continue to grow, ...
(Date:2/10/2020)... (PRWEB) , ... February 11, 2020 , ... R3 Medical ... for March 11-12th, 2020 in Las Vegas. The training consists of thread lift placement ... 988-6343 to register. , PDO thread lifts represent an excellent alternative currently for nonoperative ...
(Date:2/10/2020)... ... ... Sweet Trail Mix is a blend of keto approved nuts, unsweetened coconut and sugar free ... protein and 3 grams of net carbs with zero added sugars. Unlike most trail mixes, ... keto trail mix on the market. , The trail mix consists of only 9 ingredients, ...
(Date:2/10/2020)... ... 2020 , ... Real Food Blends , makers of 100% real food ... revolution in the medical community, is proud to announce the recipient of its 2nd ... each year during Feeding Tube Awareness Week . Feeding Tube Awareness Week is ...
Breaking Medicine News(10 mins):
(Date:2/13/2020)... , ... February 13, 2020 , ... Results of a ... show that they are maintaining a generally positive outlook on the state of their ... Asked if they are better off today than a year ago, 43% said they ...
(Date:2/11/2020)... (PRWEB) , ... February 11, 2020 , ... ... first aid and other safety measures, is offering courses for hospital and other ... is a requirement for medical practitioners like nurses, doctors, and other staff members, ...
(Date:2/11/2020)... LA JOLLA, Calif. (PRWEB) , ... February 11, 2020 , ... ... Jolla Laser Vision & Eye Center run by Dr. Daniel Coden, Dr. Arthur Perry, ... Perry, Pratt, and Coden have served patients in the La Jolla and San Diego ...
Breaking Medicine Technology:
Cached News: