PCRM initiated development of the assay in 2002 after launching a clinical trial examining the effects of a low-fat vegan diet on diabetes. The only insulin test kits on the market at the time used two cruelly derived animal ingredients--fetal calf serum, a slaughterhouse byproduct that can harbor bacteria and viruses, and cells incubated in the abdomens of live mice, a painful procedure banned in several European countries but still legal in the United States. No one had ever manufactured an insulin assay kit without the animal serum, and numerous laboratories told PCRM it couldn't be done.
The resulting alternative, one grown in a synthetic medium, proved to be as accurate as the existing insulin testing method, and costs the same. Linco has begun manufacturing the animal-serum-free kit and offers it to researchers in the United States and abroad. The cruelty-free kit is expected to sell particularly well in Europe, where laboratories are concerned about bovine spongiform encephalopathy (mad cow disease) being transmitted in animal serum.
"Our success shows that a little ingenuity can do a lot to reduce the cruelty involved in medical testing," says Megha Even, M.S., the PCRM research analyst who headed up R&D on the assay. "If scientists put more effort into developing alternatives to the use of animals in medical research and testing, we could alleviate animal suf
'"/>
Contact: Jeanne S. McVey
jeannem@pcrm.org
202-686-221-0316
Physicians Committee for Responsible Medicine
12-Dec-2005