HOME >> MEDICINE >> NEWS
Drug-eluting stent controversy explored in the American Heart Hospital Journal

Shelton, Conn. - August 08, 2007 The Summer 2007 issue of The American Heart Hospital Journal explores one of the pivotal issues in cardiology today, the drug-eluting stent (DES). Through commentaries from ten leading national and international specialists, the issue presents a comprehensive discussion on the explosive growth and the potential risks of DESs.

The issue reports on the initial enthusiasm for drug-eluting stents, the great advances made possible by their use, and explores the significance of the benefits and disadvantages revealed through their high-volume adoption.

Dr. Ulrich Sigwart of University Hospital in Geneva, Switzerland, author of one of the studies, examines the sobering current appraisal of DES use, in contrast to the triumphs of their early success. Subacute stent thrombosis due to incomplete intimal coverage, the formation of blood clots that can occur when the inner layers of blood vessels are not fully treated, remains the Achilles heel of DES use, says Dr. Sigwart. The polymer matrix used for the delivery of drugs, which clearly induces inflammatory responses, may, in part, be responsible for very late thrombosis.

Dr. Renu Virmani and colleagues at the CVPath Institute of Gaithersburg, Maryland base the judgments in their article on the evidence obtained through pathologic studies of patients dying after stent implantation. These data indicate that DESs cause both substantial impairment in arterial healing characterized by lack of complete re-endothlialization (the re-healing of the inner surfaces of vessels after stenting) and persistence of fibrin, a protein that indicates blood clotting, when compared with bare metal stents. This delayed healing is the primary substrate underlying all cases of late DES thrombosis at autopsy.

In contrast, Drs. Williams and Abbott, of Brown Medical School and affiliated with Rhode Island Hospital, note, DESs are a revolutionary advancement in interventional
'"/>

Contact: Sean Wagner
swagner@bos.blackwellpublishing.com
781-388-8550
Blackwell Publishing Ltd.
8-Aug-2007


Page: 1 2

Related medicine news :

1. Drug-eluting and absorbable stents push interventional frontiers
2. Drug-eluting stents outperform radiation treatment for coronary restenosis in bare metal stents
3. Drug-eluting stents may cause allergic reactions
4. Drug-eluting stents successfully treat vein-graft disease
5. SCAI news: Drug-eluting stents prove mettle in heart attack patients
6. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
7. New study counts the economic cost of persistent pain in Australia
8. New biodegradable magnesium stents for coronary arteries
9. Emory University researchers find persistent and severe asthma associated with obesity
10. Persistent smokers may have higher risk to become depressed than never smokers
11. Long-term anti-clotting therapy sweetens stenting outcomes in diabetic patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/22/2019)... ... October 22, 2019 , ... Mosaic Gardens at ... the hearts and minds of the architecture and affordable housing industries, amassing five ... to get this building and community to the finish line," said Rebecca Clark, ...
(Date:10/22/2019)... (PRWEB) , ... October 22, 2019 , ... ... a new medical robot that uses minimally invasive technologies to safely and accurately ... men. , Haichong (Kai) Zhang , assistant professor in biomedical engineering and ...
(Date:10/22/2019)... Va. (PRWEB) , ... October 23, 2019 , ... ... CenterWatch Webinar, Sponsored by Cmed Technology, Wednesday, Oct. 30, 2019 ? 11:00 a.m.-12 ... biotech and CROs wrestle with such questions. , Find answers., Mark the calendar ...
(Date:10/19/2019)... ... October 18, 2019 , ... Health care merger and acquisition ... to 408, compared with the previous quarter and was 15% lower than the 478 ... totaled $51.5 billion, down 63% compared with the previous quarter’s extraordinary $139.1 billion. It ...
(Date:10/19/2019)... ... October 18, 2019 , ... Today, Guide Dogs for the Blind ... by creating exceptional partnerships between people, guide dogs and communities, kicks off the organization’s ... are coming together as a community for the event to celebrate GDB’s mission and ...
Breaking Medicine News(10 mins):
(Date:10/22/2019)... ... October 22, 2019 , ... ... Physician Practice Management Software, SaaS platform and Revenue Cycle services company announced ... company, to be the exclusive platform powering PracticeSuite’s next-generation patient engagement for ...
(Date:10/22/2019)... ... October 22, 2019 , ... Remote Medical Technologies (RMT) ... of Cytopathology (ASC) 67th Annual Scientific Meeting in Salt Lake City November 15th ... innovative features and benefits of a high-performance HD telepathology solution that allows users ...
(Date:10/22/2019)... ... October 22, 2019 , ... The American ... Advocacy Award for Excellence in a State Issue Campaign by the Professional Women ... and the contributions of ASDSA’s Advocacy team: Kristin Hellquist, Director of Advocacy and ...
Breaking Medicine Technology:
Cached News: