HOME >> MEDICINE >> NEWS
Drug treatment before angioplasty or stent placement not beneficial for heart attack patients

A common practice for improving outcomes in patients with sudden heart attack actually offers no benefit and could cause harm, according to a review of randomised trials published online today (Tuesday February 14, 2006) by The Lancet.

Despite the lack of evidence for its safety and effectiveness, many doctors believe the practice of giving patients with sudden ST-elevation* heart attack drugs before undergoing emergency revascularisation procedures (angioplasty or stent placement**) improves outcome. However, preliminary studies have suggested this practice confers no benefit.

To investigate the effect of pre-intervention drug treatment, Ellen Keeley (University of Texas Southwestern Medical Center, Dallas, TX, USA) and colleagues reviewed data from 17 trials comparing the outcomes for ST-elevation heart attack patients assigned the drug based procedure before angioplasty/stent placement (2237) and those assigned angioplasty/stent placement alone (2267). The investigators found that more of the patients who received drugs prior to their intervention died than those who did not receive medication (106 versus 78). Pre-intervention drugs also increased the risk of non-fatal heart attack, bleeding, stroke, and the need for repeat revascularisation treatment. These increased rates were mainly seen when the pharmacological treatment was a drug that dissolved clots (thrombolytic therapy).

Dr Keeley states: "Drug facilitated angioplasty or stent placement offers no benefit over primary intervention in ST-elevation heart attack and should not be used outside the context of randomised controlled trials. Furthermore facilitated interventions with thrombolytic-based regimens should be avoided." (Quote by e-mail; not in paper)

In an accompanying Comment Drs. Gregg Stone (Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY, USA) and Bernard Gersh (Mayo Clinic, Rochester, MN, USA) state: "The results of thi
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
13-Feb-2006


Page: 1 2

Related medicine news :

1. Spot on treatment for acne
2. New treatment boosts muscle function in myasthenia gravis
3. New treatment effective in counteracting cocaine-induced symptoms
4. UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
5. Preventive treatments in elderly people needs rethinking
6. Osteoporosis screening and treatment may be cost-effective for selected older men
7. Quality of treatment guidelines
8. Green tea holds promise as new treatment for inflammatory skin diseases
9. Many heart attack patients still not getting emergency clot-busting treatment
10. Electric fields have potential as a cancer treatment
11. New algorithm matches any tumor cells to best possible anti-cancer treatments

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/21/2017)... ... 2017 , ... “Kids aren't born knowing how to regulate their emotions any ... Founder of St. Louis-based positive education company Generation Mindful. To help with that daunting ... 21st. , The kit uses colorful, engaging and educational illustrations and games to ...
(Date:7/21/2017)... ... July 21, 2017 , ... In the first prospective ... Multicenter Orthopaedics Outcome Network (MOON) demonstrated that patients could perform sports-related functions and ... levels decline over time. The study, presented today at the American Orthopaedic ...
(Date:7/20/2017)... , ... July 20, 2017 , ... TransPixel Volume 2 ... two clips in the FCPX timeline. This effect isolates horizontal and vertical lines of ... package contains either a rotating or flipping animation and can be changed using a ...
(Date:7/20/2017)... 2017 (PRWEB) , ... July ... ... global provider of enterprise-grade IT operations analytics and application performance monitoring (APM) ... of world’s largest healthcare services providers. , According to Peter Ohrenberger, sales ...
(Date:7/20/2017)... ... July 20, 2017 , ... ... in which their iMedSecure™ comes included with each system installation. RMT’s iMedHD2™ ... to remote participants for real-time collaboration and immediate decision-making requirements. While never ...
Breaking Medicine News(10 mins):
(Date:7/21/2017)... know that PhRMA member companies invested $65.5 billion in research and ... generics and the supply chain account for 14 percent of total ... (7 percent)? Or that the United States ... high-growth biopharmaceutical startups? ... The biopharmaceutical industry accounts for 1 ...
(Date:7/14/2017)... , July 14, 2017 Endo International plc (NASDAQ: ... Tuesday, August 8, 2017.  Members of its senior management team will ... open at 8:30 a.m. ET. The dial-in number ... 497-0462, International (678) 509-7598, and the passcode is 45397076. Please dial ... A replay of the call will ...
(Date:7/12/2017)... 12, 2017 CarpalAID is a revolutionary new product that ... Carpal tunnel syndrome affects more than 8 million people ... rate of men. The common methods of treating CTS are painful ... hand braces or gloves. ... CarpalAID is a clear patch worn on the ...
Breaking Medicine Technology:
Cached News: