HOME >> MEDICINE >> NEWS
Drug treatment before angioplasty or stent placement not beneficial for heart attack patients

A common practice for improving outcomes in patients with sudden heart attack actually offers no benefit and could cause harm, according to a review of randomised trials published online today (Tuesday February 14, 2006) by The Lancet.

Despite the lack of evidence for its safety and effectiveness, many doctors believe the practice of giving patients with sudden ST-elevation* heart attack drugs before undergoing emergency revascularisation procedures (angioplasty or stent placement**) improves outcome. However, preliminary studies have suggested this practice confers no benefit.

To investigate the effect of pre-intervention drug treatment, Ellen Keeley (University of Texas Southwestern Medical Center, Dallas, TX, USA) and colleagues reviewed data from 17 trials comparing the outcomes for ST-elevation heart attack patients assigned the drug based procedure before angioplasty/stent placement (2237) and those assigned angioplasty/stent placement alone (2267). The investigators found that more of the patients who received drugs prior to their intervention died than those who did not receive medication (106 versus 78). Pre-intervention drugs also increased the risk of non-fatal heart attack, bleeding, stroke, and the need for repeat revascularisation treatment. These increased rates were mainly seen when the pharmacological treatment was a drug that dissolved clots (thrombolytic therapy).

Dr Keeley states: "Drug facilitated angioplasty or stent placement offers no benefit over primary intervention in ST-elevation heart attack and should not be used outside the context of randomised controlled trials. Furthermore facilitated interventions with thrombolytic-based regimens should be avoided." (Quote by e-mail; not in paper)

In an accompanying Comment Drs. Gregg Stone (Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY, USA) and Bernard Gersh (Mayo Clinic, Rochester, MN, USA) state: "The results of thi
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
13-Feb-2006


Page: 1 2

Related medicine news :

1. Spot on treatment for acne
2. New treatment boosts muscle function in myasthenia gravis
3. New treatment effective in counteracting cocaine-induced symptoms
4. UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
5. Preventive treatments in elderly people needs rethinking
6. Osteoporosis screening and treatment may be cost-effective for selected older men
7. Quality of treatment guidelines
8. Green tea holds promise as new treatment for inflammatory skin diseases
9. Many heart attack patients still not getting emergency clot-busting treatment
10. Electric fields have potential as a cancer treatment
11. New algorithm matches any tumor cells to best possible anti-cancer treatments

Post Your Comments:
(Date:4/1/2015)... Nike Golf Camps has expanded with the ... Florida. These programs are specifically designed for the competitive ... golf-intensive environment and to learn about the college recruiting ... coaching legend, Rick LaRose, spends significant time evaluating each ... it pertains to the recruiting and college search process, ...
(Date:4/1/2015)... Poisonous plants (poison ivy, oak and ... recent years, increasing significantly in number and rash-causing potency. ... to poison plants (according to the American Academy of ... summer adventures in nature, they should be aware that ... greater than ever. This year, Ivarest adds a new ...
(Date:3/31/2015)... (PRWEB) March 31, 2015 Due ... started to hire more caregivers, staffing personnel, and ... and care managers within the Greater Los Angeles ... training institution, 1Heart Caregiver University has firmed up ... its mission to provide quality in-home care through ...
(Date:3/31/2015)... 01, 2015 Every day a new ... American diet) contains things banned in other countries, and ... every year. AlignLife Chiropractic & Natural Health Centers believe ... their communities they can reduce the future development of ... each AlignLife clinic offers workshops at no charge in ...
(Date:3/31/2015)... March 31, 2015 As the demand ... is pledging to have a mobile-friendly website online sometime ... part of Chunk Fitness’ continued commitment to bring the ... user base. All of the same great fitness information ... will be substantially easier to read while browsing on ...
Breaking Medicine News(10 mins):Health News:US Sports Camps and Nike Golf Camps to Host Golf Development Camps in Arizona and Florida 2Health News:US Sports Camps and Nike Golf Camps to Host Golf Development Camps in Arizona and Florida 3Health News:New Ivarest Poison Ivy Itch Spray Provides All-Day Comfort 2Health News:1Heart Ends 1st Quarter of the Year With 1Heart Caregiver University Training of New Staff and Commits To Provide More Jobs For Year 2015 2Health News:1Heart Ends 1st Quarter of the Year With 1Heart Caregiver University Training of New Staff and Commits To Provide More Jobs For Year 2015 3
(Date:3/31/2015)... Medela has announced the addition of ... Motion™-Endure personal pumps to its Negative Pressure Wound ... new devices, along with the Invia ® ... innovative, high-quality NPWT solutions, designed to provide safe ... "We are happy to be able to ...
(Date:3/31/2015)... 2015   Halyard Health (NYSE: HYH ... awarded a new purchasing agreement with HealthTrust ... 1, 2015, Halyard,s standard and ASTM-rated face masks ... be available to HealthTrust members made up of 1,350 ... centers, physician practices and alternate care facilities. ...
(Date:3/31/2015)... VANCOUVER, British Columbia , March 31, 2015 ... IMLFF), a clinical stage biopharmaceutical company that specializes ... announced the appointment of Paul C. Anderson ... Anderson is a pharma industry veteran who brings ... Dr. Anderson is a synthetic organic ...
Breaking Medicine Technology:Medela Launches Product Line to Support Individualized Care For Negative Pressure Wound Therapy Patients 2Halyard Health Signs First GPO Contracts As Independent Company 2Halyard Health Signs First GPO Contracts As Independent Company 3InMed Pharmaceuticals Strengthens Scientific Advisory Board 2InMed Pharmaceuticals Strengthens Scientific Advisory Board 3InMed Pharmaceuticals Strengthens Scientific Advisory Board 4
Cached News: