HOME >> MEDICINE >> NEWS
Drug treatment slows macular vision loss in diabetics

A drug commonly used to slow the loss of central vision has shown promise in stemming a common precursor of blindness in diabetics, which involves the same central light-sensitive area of retina, Johns Hopkins Wilmer Eye Institute scientists report.

Encouraged by the effect of ranibuzumab in people with macular degeneration, the Hopkins researchers injected the drug into the eyes of 10 people losing their sight from macular edema, one of many complications of diabetes and a first stage of diabetic retinopathy.

Over the course of several months of therapy, every patient in the preliminary Hopkins study could read at least two more lines on the standard eye chart, the researchers said. Moreover, the thickness of the patients maculae, the central part of the retina responsible for seeing fine details, decreased an average of 85 percent. The American Journal of Ophthalmology published the teams findings in their December issue.

"The results are impressive," says Quan Dong Nguyen, M.D., M.Sc., an assistant professor of ophthalmology at the Wilmer Eye Institute at Johns Hopkins, "although we will not know until we begin a larger clinical trial what the long-term benefits of the drug might be."

The Hopkins group believes that ranibuzumab interferes with a protein that spurs the growth of unwanted blood vessels in the back of the eye. Vascular endothelial growth factor, or VEGF, is released when the oxygen supply in the eye is restricted by blood vessel damage related to diabetes.

In a self-preserving attempt to acquire more oxygen, the VEGF signals for the creation of new blood vessels, which almost always damage, rather than improve, vision by blocking lights entry onto the retina.

"Weve suspected for awhile that ranibuzumabs ability to shut down VEGFs signaling would do the trick because its highly likely that VEGF is the culprit when it comes to diabetic macular edema," says Nguyen.

More th
'"/>

Contact: Jeff Ventura
jventur4@jhmi.edu
410-955-7832
Johns Hopkins Medical Institutions
15-Dec-2006


Page: 1 2

Related medicine news :

1. Spot on treatment for acne
2. New treatment boosts muscle function in myasthenia gravis
3. New treatment effective in counteracting cocaine-induced symptoms
4. UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
5. Preventive treatments in elderly people needs rethinking
6. Osteoporosis screening and treatment may be cost-effective for selected older men
7. Quality of treatment guidelines
8. Green tea holds promise as new treatment for inflammatory skin diseases
9. Many heart attack patients still not getting emergency clot-busting treatment
10. Electric fields have potential as a cancer treatment
11. New algorithm matches any tumor cells to best possible anti-cancer treatments

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/6/2019)... , ... December 06, 2019 , ... ... recognized for its innovations and excellence in patient care. On December 12th, Hartford ... of excellence at the Health Care Heroes Awards at the Hartford Marriott. , ...
(Date:12/6/2019)... , ... December 06, 2019 , ... Allegheny Health Network ... Dr. Gyure, who joined AHN from WVU Medicine in May 2018, previously served as ... has served as interim chair since October and is also part of the pathology ...
(Date:12/6/2019)... ... December 06, 2019 , ... COMPLIANCY GROUP is proud ... Wyoming Medical Society. Compliancy Group is dedicated to educating and assisting Wyoming Medical ... adhere to the standards set forth by the Health Insurance Portability and Accountability ...
(Date:12/6/2019)... ... ... TIME For Kids (TFK) revealed the first-ever list of the World’s ... that are tailored to the interests of kids. The list identifies The Children’s Museum ... TIME for Kids gathered nominations from its network of TFK Kid Reporters ...
(Date:12/5/2019)... ... December 05, 2019 , ... A cohort ... (HRUS) technology to help their patients more easily detect ruptured silicone gel implants. ... this study and reporting on his experience. While the FDA currently recommends regular ...
Breaking Medicine News(10 mins):
(Date:12/9/2019)... , ... December 09, 2019 , ... ... most people contend with are not ‘sebaceous,’” notes Dr. Robert Levine, a dual-board-certified ... epidermoid – also called ‘epidermal’ – cysts, which have their own distinct structure.” ...
(Date:12/8/2019)... (PRWEB) , ... December 07, 2019 , ... ... years to have over 700 weekly ongoing face-to-face mutual support groups in 32 ... nicotine addiction. , Nicotine Anonymous members also provide several daily phone and internet ...
(Date:12/6/2019)... ... December 06, 2019 , ... In order to help pharmacies ... introducing the CSEDOIC luminaire series. CSEDOIC fixtures are designed for healthcare cleanrooms, where ... hazardous drugs (HDs) and HD-active pharmaceutical ingredients from the original container be done ...
Breaking Medicine Technology:
Cached News: