HOME >> MEDICINE >> NEWS
Dual therapy works best for controlling asthma

A combination of airway-opening drugs and inhaled inflammation-reducing steroids works better at preventing severe asthma attacks than a normal dose of steroids alone, according to a new review of recent studies.

However, higher doses of steroids seem to be just as effective as the combination therapy in preventing these attacks, a second review concludes.

The studies focus on the effects of long acting beta-2 agonist (LABA) drugs. Unlike "rescue" inhalers, which can immediately open airways during an asthma attack, LABA medications keep bronchial airways relaxed and open over a 12-hour period. The drugs include salmeterol, which is sold under the brand name Serevent and is also an ingredient in the Advair inhaler, and formoterol, sold under the brand name Foradil.

Asthma patients who used both LABA medication and an inhaled steroid were significantly less likely to have a severe asthma flare-up requiring treatment with an injected or swallowed steroid than patients taking the steroid alone, according to Muireann Ni Chroinin, M.D., of the Norfolk and Norwich University Hospital in England, and colleagues.

The reviews appear in the current issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

The rate of severe attacks dropped from 27 percent to 22 percent in patients taking the combination therapy. Ni Chroinin and colleagues calculate that 18 patients would need to be treated with LABA for one year to prevent at least one patient from having such an attack.

Combination therapy also improved overall lung function, increased the number of days where patients said they felt free of asthma symptoms and decreased the patients' use of rescue inhalers, compared to inhaled steroids alo
'"/>

Contact: Muireann N Ni Chroinin
muireann.nichroinin@nnuh.nhs.uk
Center for the Advancement of Health
18-Oct-2005


Page: 1 2 3

Related medicine news :

1. Chemotherapy with bevacizumab increases risk of blood clots in arteries
2. Nonsmall cell lung cancer -- chemotherapy before surgery appears better than surgery alone
3. Stroke in nonvascular atrial fibrillation -- anti-coagulants better than anti-platelet therapy
4. Hormone therapy offers new hope for ovarian cancer patients
5. Borderline personality disorder shows improvements with intensive psychotherapy
6. Trial shows circulating tumor cells predict how prostate cancer patients do with chemotherapy
7. Chemotherapy may enhance the effectiveness of brain tumor vaccines
8. Brain-boosting pill alleviates post-chemotherapy fogginess
9. Adding radioimmunotherapy to chemo may help patients with lymphoma
10. Pre-operative chemotherapy does not increase survival rates for nonsmall cell lung cancer
11. OHSU Cancer Institute shows findings of immunotherapy vaccine in prostate cancer patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2019)... ... 13, 2019 , ... New Hampshire-based Vera Roasting Company , makers of ... of its line of CBD-infused coffees with the release of a new higher-dosage organic ... , “We are excited to expand our CBD-infused product lines to include a ...
(Date:8/14/2019)... ... August 13, 2019 , ... In a recent Trivedi ... of doubt in your belief systems. , “Doubt can obliterate your old beliefs,” said ... path to examining them to expand your understanding and your awareness. Trust that the ...
(Date:8/14/2019)... ... ... While it is commonly understood that good nutrition promotes general health, consumers are ... and, in some cases, reverse certain medical conditions, according to health and wellness research ... trying to manage a health or medical condition by making healthy food and beverage ...
(Date:8/12/2019)... ... ... Eco Pump Services is an experienced, licensed, and insured company ... years, Eco Pump Services has served customers with excellence and exceptional customer service in ... steady five-star ratings and excellent customer reactions throughout numerous online review sources have led ...
(Date:8/12/2019)... ... 2019 , ... Parents craving a nutritious and delicious snack for their kids ... feed children in need. IsaKids® Super Smoothie is one of three products launched yesterday ... health and wellness company also debuted Organic Greens, an updated version of its Isagenix ...
Breaking Medicine News(10 mins):
(Date:8/15/2019)... , ... August 15, 2019 , ... ... Private Client service for intended parents who are looking for egg donors, gestational ... patients who are looking for the ultimate concierge service and hands-on help in ...
(Date:8/14/2019)... (PRWEB) , ... August 14, 2019 , ... Cambria ... 2,721 on Inc. Magazine’s Inc. 5000 list . The Inc. 5000 is the ... significant designation for Cambria,” said Cambria CEO Robert Rodriguez. “We have a committed and ...
(Date:8/14/2019)... ... August 14, 2019 , ... Canyon State Veterinary Specialties ... With pet care at the forefront of design, the project includes dedicated spaces ... Twelve exam rooms, office space and a dedicated grieving space round out this ...
Breaking Medicine Technology:
Cached News: