Early statin therapy for patients with acute coronary syndromes reduces death, cardiovascular events

Early, intensive therapy with statin medications reduces death and cardiovascular events for patients who have had heart attacks or other acute heart events, according to an analysis of previous studies published in the September 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Statins, commonly taken to lower cholesterol levels, have clearly been shown to benefit patients with cardiovascular disease, according to background information in the article. However, it is less clear whether these drugs provide a short-term benefit when given immediately to patients hospitalized for acute coronary syndrome, the group of heart disorders associated with myocardial ischemia (a lack of blood flow to the heart). In addition to reducing cholesterol, statins may stabilize the amount of plaque build-up in arteries, reduce inflammation, prevent blood clotting, reduce blood pressure and improve the functioning of blood vessels, all of which could improve outcomes for patients with acute coronary syndrome.

Eddie Hulten, M.D., M.P.H., and colleagues at Walter Reed Army Medical Center, Washington, D.C., and Uniformed Services University of the Health Sciences, Bethesda, Md., analyzed the results of 13 previous clinical trials of early, intensive statin therapy (begun within 14 days of hospitalization for acute coronary syndrome) involving 17,963 adults with acute coronary syndrome. The studies compared intensive (high-dose) statins with low-dose statins, placebo for four months followed by a lower dose of statins, placebo alone or usual care per the treating physicians' discretion. The participants had an average age of 60 and 76 percent were male.

"This systematic review provides evidence that early, intensive therapy with statins is associated with a reduction of adverse cardiovascular outcomes, particularly cardiovascular death, unstable angina and revascularization when prescribed within 14 days of hospitalization f

Contact: Walter Reed Army Medical Center public affairs
JAMA and Archives Journals

Page: 1 2

Related medicine news :

1. Early-childhood intervention may improve well-being through young adulthood
2. Early-morning Friday classes may prevent students from getting sloppy on thirsty Thursdays
3. Early education for the health care team -- Bringing nursing and medical students together
4. Early onset of poor bone mineralization revealed in children with cystic fibrosis
5. Early sex may lead teens to delinquency, study shows
6. Early switch to an aromatase inhibitor increases survival
7. Early results indicate radiofreqency ablation useful in treating ovarian cancer metastasis
8. Early trial shows H5N1 influenza vaccine safe and effective in humans at low doses
9. Early warning test for Parkinsons receives national recognition
10. Early-onset of diabetes associated with increased risk of kidney disease and death before age 55
11. Early drinking linked to risk for alcohol dependence

Post Your Comments:

(Date:11/28/2015)... ... , ... Safe storage for contraceptive devices may not always be easy to ... and the other from Bradley Beach, New Jersey, there is an easy solution to ... to replace NuvaRings more often than necessary. As such, it affords peace of mind ...
(Date:11/27/2015)... ... November 28, 2015 , ... There is only one major question facing ... last year? , This question has not been an easy question to answer. Especially ... age and the younger workforce don’t share the same discipline around working long hours. ...
(Date:11/27/2015)... ... 27, 2015 , ... The rapid speed at which Americans ... more care is needed, especially with Alzheimer’s, dementia and other cognitive conditions becoming ... The forgotten part of this equation: 80 percent of medical care occurs in ...
(Date:11/27/2015)... ... 27, 2015 , ... Lizzie’s Lice Pickers just announced a special promotion that ... of their purchase of lice treatment product. In addition, customers will receive a complimentary ... spokesperson. “Finding lice is a sure way to ruin the holidays, so we encourage ...
(Date:11/27/2015)... , ... November 27, 2015 , ... ... of progress through sharing, the 2016 Building Better Radiology Marketing Programs ... will begin on Sunday, March 6, 2016, at Caesars Palace in Las Vegas ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ... the "2016 Future Horizons and Growth Strategies ... Supplier Shares, Country Segment Forecasts, Competitive Intelligence, Emerging ... --> --> This ... the Italian therapeutic drug monitoring market, including emerging ...
(Date:11/25/2015)... , Nov. 25, 2015  Amgen (NASDAQ: AMGN ... Application (BLA) with the United States ... 501, a biosimilar candidate to Humira ® (adalimumab). ... application submitted to the FDA and represents Amgen,s first ... Sean E. Harper , M.D., executive vice president of ...
(Date:11/25/2015)... Nov. 25, 2015  ARKRAY USA ... to provide evidence demonstrating the accuracy of its blood ... on Insulin Resistance, Diabetes and Cardiovascular Disease in ... the Company,s GLUCOCARD ® 01 meter and the ... requirements. The ability to accurately measure glucose levels in ...
Breaking Medicine Technology:
Cached News: