HOME >> MEDICINE >> NEWS
Early statin therapy for patients with acute coronary syndromes reduces death, cardiovascular events

Early, intensive therapy with statin medications reduces death and cardiovascular events for patients who have had heart attacks or other acute heart events, according to an analysis of previous studies published in the September 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Statins, commonly taken to lower cholesterol levels, have clearly been shown to benefit patients with cardiovascular disease, according to background information in the article. However, it is less clear whether these drugs provide a short-term benefit when given immediately to patients hospitalized for acute coronary syndrome, the group of heart disorders associated with myocardial ischemia (a lack of blood flow to the heart). In addition to reducing cholesterol, statins may stabilize the amount of plaque build-up in arteries, reduce inflammation, prevent blood clotting, reduce blood pressure and improve the functioning of blood vessels, all of which could improve outcomes for patients with acute coronary syndrome.

Eddie Hulten, M.D., M.P.H., and colleagues at Walter Reed Army Medical Center, Washington, D.C., and Uniformed Services University of the Health Sciences, Bethesda, Md., analyzed the results of 13 previous clinical trials of early, intensive statin therapy (begun within 14 days of hospitalization for acute coronary syndrome) involving 17,963 adults with acute coronary syndrome. The studies compared intensive (high-dose) statins with low-dose statins, placebo for four months followed by a lower dose of statins, placebo alone or usual care per the treating physicians' discretion. The participants had an average age of 60 and 76 percent were male.

"This systematic review provides evidence that early, intensive therapy with statins is associated with a reduction of adverse cardiovascular outcomes, particularly cardiovascular death, unstable angina and revascularization when prescribed within 14 days of hospitalization f
'"/>

Contact: Walter Reed Army Medical Center public affairs
202-782-7177
JAMA and Archives Journals
25-Sep-2006


Page: 1 2

Related medicine news :

1. Early-childhood intervention may improve well-being through young adulthood
2. Early-morning Friday classes may prevent students from getting sloppy on thirsty Thursdays
3. Early education for the health care team -- Bringing nursing and medical students together
4. Early onset of poor bone mineralization revealed in children with cystic fibrosis
5. Early sex may lead teens to delinquency, study shows
6. Early switch to an aromatase inhibitor increases survival
7. Early results indicate radiofreqency ablation useful in treating ovarian cancer metastasis
8. Early trial shows H5N1 influenza vaccine safe and effective in humans at low doses
9. Early warning test for Parkinsons receives national recognition
10. Early-onset of diabetes associated with increased risk of kidney disease and death before age 55
11. Early drinking linked to risk for alcohol dependence

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... 2020 , ... Dr. Chang has over 20 years of ... developmental disabilities, as well as supporting staff in caring for patients and families. ... and staff development. She joined the company in 2015 as Chief of Clinical ...
(Date:8/29/2020)... ... , ... When professor and author Randy Pausch was diagnosed with pancreatic cancer, ... than become melancholic, however, he put together a final lecture in Carnegie Hall in ... a negative situation and turned it into something that inspired millions of people worldwide. ...
(Date:8/28/2020)... ... August 28, 2020 , ... WHAT , Hespiro™ ... patients with respiratory conditions, including COVID-19, while reducing the need for scarce mechanical ... captures exhaled gas and scrubs it free of carbon dioxide in a completely ...
(Date:8/28/2020)... ... 28, 2020 , ... With in-person gluten-free events being canceled ... the specialty-diet community connect with great, gluten-free brands. At the Online Nourished ... with brands & watch over 50 educational classes... all online from the comfort ...
(Date:8/28/2020)... ... August 28, 2020 , ... Ziegler, a specialty investment ... investment in Synchronous Health, a tech-enabled behavioral health and well-being solutions provider. ... empathy with artificial intelligence (AI) to increase access and quality of behavioral health ...
Breaking Medicine News(10 mins):
(Date:8/26/2020)... ... August 26, 2020 , ... ... Care Helps Sports Injuries. The infographic breaks down ways that chiropractors can help ... recovery. , According to ScripHessco “Athletes have an unusual amount of pressure and ...
(Date:8/26/2020)... ... August 26, 2020 , ... Clinical ... definitive agreement to acquire ProCE, a nationally recognized provider of continuing education ... , CEA represents a growing alliance of CME/CE and service organizations that ...
(Date:8/26/2020)... YORK (PRWEB) , ... August 26, 2020 , ... ... nation’s largest non-profit organization devoted to funding innovative lymphoma research and serving the ... its 25th Anniversary with a special virtual LRF Gala and Charity Auction ...
Breaking Medicine Technology:
Cached News: