HOME >> MEDICINE >> NEWS
Elevated GGT enzyme may predict risk of death from cardiovascular disease

A simple blood test may identify people who have an increased risk of dying from cardiovascular disease, researchers report in Circulation: Journal of the American Heart Association.

The test measures gamma-glutamyl transferase (GGT) an enzyme produced primarily by the liver and catalyzes glutathione, the main antioxidant in the body. The enzyme is elevated in some forms of liver disease, so physicians use GGT levels to detect liver damage and alcohol abuse.

In analyzing data from a long-term study involving more than 160,000 Austrian adults, the researchers found that the higher a person's blood level of GGT, the greater the risk of cardiovascular death. The levels are given in units per liter (U/l) of blood. Normal low is less than 9 U/l for women and less than 14 U/l for men. A moderately high value for GGT is 18 U/I for women and 28 U/I for men. High levels (twofold elevated) are more than 36 U/I for women and 56 U/I for men.

"People with high GGT had more than a 1.5-fold risk of dying from cardiovascular diseases in comparison to people with normal low levels of GGT," said senior author Hanno Ulmer, Ph.D. "For people under 60 years of age, this risk is even higher, amounting to more than two-fold. "Over the past decade, some small studies have suggested a link between high GGT and cardiovascular disease," said Ulmer, associate professor of medical statistics at the Innsbruck Medical University in Austria.

Several years ago, Italian researchers reported that elevated GGT could indicate early atherosclerosis. Ulmer and his colleagues investigated the researchers' findings. They examined medical data collected from 19852001 from 163,944 (98.4 percent) of the then-enrolled volunteers in the Vorarlberg Health Monitoring and Promotion Program. This is an ongoing study in Austria's westernmost province that examines risk factors for chronic diseases.

The participants included 74,830 men and 89,114 women, age 19 or older when t
'"/>

Contact: Carole Bullock
carole.bullock@heart.org
214-706-1279
American Heart Association
26-Sep-2005


Page: 1 2 3

Related medicine news :

1. Elevated testosterone kills nerve cells
2. Elevated rates of mental health problems among survivors of tsunami
3. Elevated blood levels of a protein are linked to asbestos-induced cancers
4. Elevated CRP can foil diets ability to lower cholesterol
5. Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
6. Scientists develop method to track immune system enzyme in live animals
7. Coenzyme Q10 does not improve Parkinsons disease symptoms
8. Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment
9. New class of HIV drug attacks previously untargeted enzyme
10. Biologists learn structure of enzyme needed to power molecular motor
11. Scientists stop colon cancer growth in mice by blocking just one enzyme

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a ... and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is ... to some of the world’s leading providers of cereal and other breakfast foods. Its ...
(Date:6/25/2016)... Washington, D.C. (PRWEB) , ... June 25, 2016 ... ... will discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June ... share their work on several important health care topics including advance care planning, ...
(Date:6/25/2016)... Beach, CA (PRWEB) , ... June 25, 2016 , ... ... UCLA with Magna Cum Laude and his M.D from the David Geffen School of ... Diego and returned to Los Angeles to complete his fellowship in hematology/oncology at the ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may ... to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To ... for healthy coping following a traumatic event. , Trauma sufferers tend to feel a ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda ... orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including ... accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
(Date:6/24/2016)... , June 24, 2016 The Academy of ... recommendations that would allow biopharmaceutical companies to ... entities that make formulary and coverage decisions, a move ... of new medicines. The recommendations address restrictions ... appear on the drug label, a prohibition that hinders ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ., ... developing innovative inhaled drugs, announced today that it was ... Investments reconstituted its comprehensive set of U.S. and ... "This is an important milestone for Pulmatrix," said Chief ... shareholder awareness of our progress in developing drugs for ...
Breaking Medicine Technology:
Cached News: