Employers who recognize the impact of migraine may help to improve workplace pr...( symptom relief and 79 percent reported...),Health

TOPAMAX Improved Workplace Productivity Pooled Results from Three Trials

Results of this data analysis conducted by Philadelphias Thomas Jefferson University, suggested that 100 mg per day of TOPAMAX, approved by the U.S. Food and Drug Administration (FDA) for migraine prevention in adults, may help to improve workplace productivity. Researchers examined pooled results from three different trials, including data recently published in The Journal of Occupational and Environmental Medicine. The findings suggested productivity improved more than two-fold among workers after beginning treatment with TOPAMAX (total lost productivity time was 13.5 hours per month prior to TOPAMAX therapy vs. 5.1 hours per month following TOPAMAX therapy).

Migraine sufferers taken from three previous phase III clinical trials were evaluated as part of the study. All were clinically diagnosed with migraine and experienced at least three to 12 migraines per month. In this analysis, the respondents completed a five-item survey each time they experienced a migraine attack, which evaluated absenteeism and presenteeism. The analysis was limited to respondents from the clinical trials who were employed, and the researchers only captured lost work hours observed during episodes of migraine.

About Migraine

Migraine is a chronic, debilitating condition that is under-diagnosed, undertreated and misunderstood. Approximately 30 million Americans suffer from migraines, and less than half are properly diagnosed with the condition. Migraines most commonly occur between the ages 30 and 49, a time when people are actively involved in the workforce. Recently, the American Migraine Prevalence and Prevention (AMPP) Study showed that almost 98 percent of people with frequent migraines take medications, but a large majority reported their lives are still negatively impacted by the
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Contact: Christy Hummel
chummel@golinharris.com
312-729-4179
Ortho-McNeil Neurologics
3-May-2007