Employers who recognize the impact of migraine may help to improve workplace pr...( pain and disability associated with mi...)

Employers who recognize the impact of migraine may help to improve workplace productivity

pain and disability associated with migraine. In addition, approximately 40 percent of frequent migraine sufferers could benefit from preventive therapy, yet only 13 percent typically are on a migraine preventive medication.

TOPAMAX is approved for migraine prevention in adults only. TOPAMAX is not for the acute treatment of migraines.

IMPORTANT SAFETY INFORMATION

Serious risks associated with TOPAMAX include lowered bicarbonate levels in the blood resulting in an increase in the acidity of the blood (metabolic acidosis), and hyperventilation (rapid, deep breathing) or fatigue. More severe symptoms of metabolic acidosis could include irregular heartbeat or changes in the level of alertness. Chronic, untreated metabolic acidosis may increase the risk for kidney stones or bone disease. Your doctor may want to do simple blood tests to measure bicarbonate levels.

Other serious risks include increased eye pressure (glaucoma), decreased sweating, increased body temperature, kidney stones, sleepiness, dizziness, confusion, and difficulty concentrating. Tell your doctor immediately if you have blurred vision or eye pain. More common side effects are tingling in arms and legs, loss of appetite, nausea, diarrhea, taste change and weight loss. Tell your doctor about other medications you take.

Contact: Christy Hummel
chummel@golinharris.com
312-729-4179
Ortho-McNeil Neurologics
3-May-2007

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