Risk of CVD in men with a history of nephrolithiasis was 1.15; the risk was highest for angina among individual outcomes analyzed. No increased stroke risk was observed. While the statistical risk for CVD in stone disease patients was modest, results correlate with other studies investigating a link between CVD and nephrolithiasis and may contribute to the etiology of stone formation and the counseling of patients.

This study will be presented in Podium Session 40, on Tuesday May 22, 2007 starting at 10:00 a.m.

GENERAL OBESITY AS MEASURED BY WAIST CIRCUMFERENCE IS PREDICTIVE OF SEVERITY OF LOWER URINARY TRACT SYMPTOMS, SEXUAL DYSFUNCTION AND COMPONENTS OF THE METABOLIC SYNDROME (Abstract 1508)

Increased body mass index (BMI) and other components of metabolic syndrome have been linked to a number of urologic disorders, including erectile and voiding dysfunction. Researchers from New York and Illinois suggest that measurement of waist circumference may be a useful predictor for the severity of lower urinary tract symptoms (LUTS) and prostate volume. Baseline parameters International Prostate Symptom Score (IPSS), prostate volume (measured by ultrasound), serum prostate-specific antigen (PSA), flow rate and erectile and ejaculatory dysfunction were gathered, along with data on the incidence of hypertension, coronary artery disease and diabetes mellitus were compared among the 88 men in the study. Men were divided into three groups based on waist circumference (30-36 inches, 36-40 inches and greater than 40 inches).

Significant positive relationships between waist circumference and prostate volume, PSA, IPSS, erectile dysfunction and ejaculatory dysfunction were observed. Flow rates were inversely related. Higher waist circumference was also associated with an increase in diabetes mellitus, hypertens
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Contact: Wendy Isett
wisett@auanet.org
410-689-3789
American Urological Association
21-May-2007