HOME >> MEDICINE >> NEWS
Experimental shingles vaccine proves effective in nationwide study

In one of the largest adult vaccine clinical trials ever, researchers have found that an experimental vaccine against shingles (zoster vaccine) prevented about half of cases of shingles--a painful nerve and skin infection--and dramatically reduced its severity and complications in vaccinated persons who got the disease. The findings appear in the June 2 issue of The New England Journal of Medicine.

The Shingles Prevention Study, conducted over 5 -years, was led by the Department of Veterans Affairs (VA) and carried out in collaboration with the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), and Merck & Co., Inc. (Whitehouse Station, NJ).

"This is very promising news for older persons," says Stephen E. Straus, M.D., an infectious diseases specialist at NIAID and Director of the NIH National Center for Complementary and Alternative Medicine, who participated in the design, oversight and conduct of the trial. "These striking results indicate for the first time that we can use a vaccine to prevent shingles, one of the most common and debilitating illnesses of aging. And among vaccine recipients who did get shingles, the episodes generally were far milder than they otherwise would have been."

"For some people, shingles can result in months or even years of misery," comments study leader Michael N. Oxman, M.D., an infectious disease specialist at the San Diego VA Healthcare System and the University of California, San Diego.

Shingles, also known as herpes zoster, is caused by reactivation of the virus that causes chickenpox. Once chickenpox infection has run its course, the virus is not eliminated; rather, it retreats to clusters of sensory nerve cells usually located near the spinal cord, where the virus persists in a dormant state. As immunity weakens with advancing age, the virus can reactivate, multiply in and damage sensory nerve cells to cause pain. It then migrates
'"/>

Contact: Laurie K. Doepel
doepel@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
1-Jun-2005


Page: 1 2 3 4

Related medicine news :

1. Experimental gene therapy abolishes arthritis pain and lessens joint damage
2. Mayo Clinic research in cardiovascular disease presented at Experimental Biology 2007
3. Experimental flu vaccine appears promising in early tests
4. Experimental ragweed therapy offers allergy sufferers longer relief with fewer shots
5. Experimental medication kicks depression in hours instead of weeks
6. Experimental vaccine protects lab animals against several strains of H5N1
7. Experimental therapies and vaccines for Ebola and Marburg viruses focus of Academy meeting
8. Tai Chi boosts immunity to shingles virus in older adults, NIH-sponsored study reports
9. Antiviral drugs may help relieve nerve pain related to shingles
10. Epidural injection does not reduce long-term pain for people with shingles
11. Traditional Chinese exercises may increase efficacy of flu vaccine

Post Your Comments:
(Date:7/29/2014)... July 29, 2014 Outsourced coding ... tripling in the number of hospitals contracting for ... 2015 deadline, according to the recently published Black ... leaders, found in the reports “Top Ranked Clinical ... now outsource Clinical documentation audit, review and programming. ...
(Date:7/29/2014)... invested $3.4 million this year to support innovative ... chronic diseases that affect more than 233,000 Canadians. ... research projects across Canada. This diverse research will ... improve our understanding (and potential treatment) of symptoms ... quality of life. , Crohn,s and Colitis ...
(Date:7/29/2014)... CHI-California Healthcare Institute today unveiled a ... C (hep C) epidemic in the U.S., the rise ... reduce human suffering. The report examines key data to ... C, while highlighting the significance of breakthroughs that have ... is a nonprofit, public policy research organization, representing leading ...
(Date:7/29/2014)... Thompson HealthDay Reporter MONDAY, ... virus that continues to rage throughout West Africa poses little ... only spreads through physical touch, and it can,t be spread ... deputy director of the National Center for Emerging & Zoonotic ... Prevention, explained in a Monday afternoon news conference. Those ...
(Date:7/29/2014)... Ill. By studying the injuries and aptitudes of ... the war, scientists are tackling -- and beginning to ... , The researchers found that brain regions that contribute ... intelligence and to emotional intelligence. This finding bolsters the ... social context of one,s life. , The ...
Breaking Medicine News(10 mins):Health News:Clinical Documentation Improvement Heats Up as Half of US Hospitals Make 2015 Preparations for ICD-10, the Rest to Rely on Outsourcers, Black Book Survey Reveals 2Health News:Clinical Documentation Improvement Heats Up as Half of US Hospitals Make 2015 Preparations for ICD-10, the Rest to Rely on Outsourcers, Black Book Survey Reveals 3Health News:Prestigious Crohn's and Colitis Canada grants fund promising Canadian research 2Health News:CHI Releases Report Highlighting Public Impact of Hepatitis C, Opportunities for Action in US 2Health News:CHI Releases Report Highlighting Public Impact of Hepatitis C, Opportunities for Action in US 3Health News:CHI Releases Report Highlighting Public Impact of Hepatitis C, Opportunities for Action in US 4Health News:CDC Downplays Ebola's Threat to the United States 2Health News:CDC Downplays Ebola's Threat to the United States 3Health News:CDC Downplays Ebola's Threat to the United States 4Health News:Team studies the social origins of intelligence in the brain 2Health News:Team studies the social origins of intelligence in the brain 3
(Date:7/29/2014)... CITY , July 29, 2014  The ... Grand American Hotel in Salt Lake City ... representing some of most respected healthcare organizations in the ... Catalyst , is an industry conference devoted to providing ... analytics,  an essential element of both accountable care initiatives ...
(Date:7/29/2014)... , July 29, 2014  Ambit Biosciences (Nasdaq: ... and development of drugs targeting unmet needs in oncology, ... second quarter operational results after closing of the NASDAQ ... A conference call hosted by Michael Martino ... management will take place on the same day at ...
(Date:7/29/2014)... TRIANGLE PARK, N.C. , July 29, 2014 ... on cloud-based drug design and development, announced today ... grant from the National Science Foundation Small Business ... valued at $150,000. Cloud Pharmaceuticals ... the development process by implementing new, innovative cloud ...
Breaking Medicine Technology:Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 2Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 3Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 4Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 5Ambit Biosciences To Announce Second Quarter 2014 Financial Results 2Cloud Pharmaceuticals Receives Phase I NSF SBIR Grant Valued at $150,000 2
Cached News: