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Exposure to fine particle air pollution linked with risk of respiratory and cardiovascular diseases

ure, which had a 1.28 percent increase in risk per 10-g/m3 increase in same-day PM2.5. Cardiovascular risks tended to be higher in counties located in the Eastern region of the United States, which included the Northeast, the Southeast, the Midwest, and the South.

"In the lung, particulate matter may promote inflammation and thereby exacerbate underlying lung disease and reduce the efficacy of lung-defense mechanisms. Cardiovascular effects may reflect neurogenic [arising in or stimulated by nerve tissues] and inflammatory processes," the authors write.

"Our findings indicate an ongoing threat to the health of the elderly population from airborne particles and provide a rationale for setting a PM2.5 National Ambient Air Quality Standard that is as protective of their health as possible," the researchers write. "The sources of particles contributing to the observed risks need to be identified so that control strategies can be targeted efficiently."


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Contact: Kenna Lowe
410-614-6029
JAMA and Archives Journals
7-Mar-2006


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