HOME >> MEDICINE >> NEWS
Fever of unknown origin: a marker for occult cancer?

EMBARGO: 00:01H (London time) Wednesday September 28, 2005. In North America the embargo lifts at 6:30pm ET Tuesday September 27, 2005. FEVER OF UNKNOWN ORIGIN: A MARKER FOR OCCULT CANCER? Fever of unknown origin might be a marker of occult cancer, according to research published online today by THE LANCET ONCOLOGY.

Fever of unknown origin is characterised by a fever of more than 3 weeks duration, temperatures of more than 38.3C and a failure to identify the origin of the fever. Underlying causes of these fevers are difficult to diagnose, but proposed causes are infections, cancers and collagen-vascular diseases. Henrik Toft Sorensen and colleagues hypothesised that patients with fever of unknown origin might have a higher risk of cancer than the general population.

To test their theory, they assessed 43 205 patients discharged for the first time from Danish hospitals after treatment for fever of unknown origin from 1977-98. Using registry data, they examined whether these patients had a higher risk of subsequent cancer than that expected based on cancer incidence in the general population. They also compared survival of these patients with cancer patients without fever, but matched for cancer site, age at diagnosis of cancer and year of cancer diagnosis.

Within the first year of follow-up after discharge from hospital, patients with fever had an increased risk of developing cancer and 399 cancers were diagnosed (standardised incidence ratio 2.3 [95%CI 2.1-2.5]). This risk was highest for haematological cancers and sarcomas and, although reduced, the overall increased risk remained after 1 year of follow-up. Some cancer patients with fever also had a worse prognosis than did the controls without fever (mortality ratio 1.4 [1.2-1.6]).

Prof Sorensen states "Heightened diagnostic effort could account for some of the association; however, after several years of follow-up, diagnostic bias should not be a major contributing
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
+1-212-633-3810
Lancet
27-Sep-2005


Page: 1 2

Related medicine news :

1. Yellow Fever
2. Benefits of testosterone treatment unknown, research shows
3. The unknown risks of arthritis
4. Daycare illness guidelines exist, but largely unknown
5. Depression linked to previously unknown dopamine regulator
6. Novel candidate biomarker for heart failure also strongly predicts risk of death
7. USC researchers show that molecular markers predict tumor recurrence
8. OHSU Cancer Institute researcher identifies protein marker for prostate cancer survival
9. Advances in screening and markers improve early detection of colorectal cancer
10. Genetic marker linked to aggressive prostate cancer
11. Genetic markers in surrounding tissues linked to breast cancer tumor grade, presence of metastases

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... "With 30 ... their specific project," said Christina Austin - CEO of Pixel Film Studios. , ... and all within Final Cut Pro X . Simply select a ProHand generator ...
(Date:6/25/2016)... ... ... Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and Mental ... exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took place ... BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive an ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort ... holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain ... Disease (SCD) is a disorder of the red blood cells, which can cause episodes ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda ... orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including ... accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. ...
(Date:6/24/2016)... ... 2016 , ... EB Medicine presented its first-ever “Issue of ... in Ponte Vedra Beach, FL. The awards honor the outstanding work of leading ... and Pediatric Emergency Medicine Practice. , “With this award, we recognize the efforts ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- Research and Markets has announced ... Applications, Technologies, Forecasts" report to their offering. ... Smart Skin, Structural Health Monitoring, Composite Smart Structures, ... involves electronic and/or electrical components and circuits that ... such as vehicle bodies or conformally placed upon ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... "The World Market for Companion Diagnostic Tests" report to ... World Market for Companion Diagnostics The World ... diagnostic and personalized medicine diagnostics. Market analysis in the report ... Diagnostics Test Market (In Vitro Diagnostic Kits) by Region (N. ...
(Date:6/24/2016)... Tenn. , June 24, 2016  Arkis ... providing less invasive and more durable cerebrospinal fluid ... in funding.  The Series-A funding is led by ... Lighthouse Fund, and other private investors.  Arkis, new ... neurosurgical instrumentation and the market release of its ...
Breaking Medicine Technology:
Cached News: