HOME >> MEDICINE >> NEWS
First-degree fetal heart block may be reversible

There is an increased risk of fetal heart problems when mothers carry particular antibodies associated with rheumatic diseases, according to an abstract presented by Yale School of Medicine researchers at the Society for Maternal-Fetal Medicine Conference February 9 in San Francisco.

Congenital heart block (CHB) is present at or before birth and impairs the heart's electrical signaling from the upper to the lower chambers. CHB carries a 20 percent death rate and nearly all survivors require pacemakers. Joshua Copel, M.D., professor in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale helped conduct the PR Interval and Dexamethasone Evaluation (PRIDE) study with a team of other researchers to evaluate an early marker of cardiac injury before there is permanent scarring.

The PRIDE group conducted a longitudinal (observational) study following over 100 women with the anti-Ro and anti-La antibodies to determine if there were early signs of fetal heart problems. They also explored whether early treatment would reverse the problems.

The team found that while first-degree fetal heart block may be reversible with the steroid drug dexamethasone, the condition could advance within as little as one week to a third-degree block, which is irreversible even with further intervention.

"Given the high recurrence rate we confirmed in this study, close monitoring and the earliest possible marker is necessary," said Copel, who plans trials of other possible treatments. "Advanced block and permanent heart damage can occur within one week of a normal echocardiogram, even a weekly evaluation may not be sufficient to detect early onset of disease."


'"/>

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University
9-Feb-2007


Page: 1

Related medicine news :

1. Benchmark fetal surgery study finds timeliness to be critical factor in success of treatment
2. Restricted fetal growth increases risk of irritable bowel syndrome
3. Improvement seen in fetal survival following preeclampsia
4. Methamphetamine use restricts fetal growth, study finds
5. Commonly used drug may prevent fetal alcohol syndrome
6. New eye movement test may help treat fetal alcohol syndrome
7. Lifestyle, rather than fetal or childhood factors, critical for adult bone health
8. A broader look at cardiac CTA images often finds diseases/disorders beyond the heart
9. Drug for cluster headaches may cause heart problems
10. Reductive stress linked to heart disease
11. Novel candidate biomarker for heart failure also strongly predicts risk of death

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2019)... ... February 19, 2019 , ... NCPDP announced today that Dave ... engagement, will deliver the luncheon keynote on Tuesday, May 7, at its ... and empowering partnerships between patients and their medical providers to NCPDP’s Annual Conference, ...
(Date:2/19/2019)... ... 19, 2019 , ... According to a recent study by Columbia University, more ... daily routines; and only 26% of widows return to their pre-loss level of life ... is one of the most tragic events that one can face. Consequently, many look ...
(Date:2/19/2019)... ... February 18, 2019 , ... AdventHealth Connerton is ... Solutions Footwear Sanitizing Stations to maximize infection control for patients and their families. ... as MRSA and C. difficile, which can be transmitted from the bottoms of ...
(Date:2/19/2019)... ... February 19, 2019 , ... ... Create Health, Wealth and Have the Life You Want!” (published by Balboa Press), ... with weight issues to release the pounds, reconnect to their dreams and attain ...
(Date:2/19/2019)... (PRWEB) , ... February 19, 2019 , ... STAR ... Supervision Program for occupational therapists beginning March 2019. The focus of the new ... discuss challenging client cases. The new Group Supervision Programs will be held on Zoom ...
Breaking Medicine News(10 mins):
(Date:2/16/2019)... ... February 15, 2019 , ... In observance ... Perio-Implant Care are urging patients to take their oral health seriously. With recent ... and dementia, and risk of pre-term birth, there is plenty to be concerned ...
(Date:2/16/2019)... ... February 15, 2019 , ... Dr. ... LAPIP™ protocol for ailing dental implants to the Northridge and surrounding areas. Dr. ... population of dentists looking to provide their patients with top-tier care without sacrificing ...
(Date:2/16/2019)... Calif. and HERSTAL, Belgium (PRWEB) , ... February ... ... that positive data and observations from multiple studies and patient registries demonstrating the ... the American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO GU), taking place ...
Breaking Medicine Technology:
Cached News: