HOME >> MEDICINE >> NEWS
Fluorescence device to diagnose atherosclerosis and tumors described at optics conference

he ability of time-resolved laser-induced fluorescence spectroscopy (TR-LIFS) to differentiate brain tumor tissue from normal brain tissue and its ability to detect arterial plaque that is vulnerable to rupture, which often leads to heart attack or stroke.

Recent atherosclerosis research has found that the composition of plaque and its "vulnerability" to rupture may be more significant than the degree of arterial blockage as a precursor to heart attack and stroke. The lipid content of vulnerable plaque is different from that of stable plaque, and areas containing vulnerable plaque are infiltrated by immune system cells called macrophages. This inflammatory process weakens the plaque's thin, fibrous cap, often leading to rupture and formation of blood clots that could plug the blood vessel. A variety of technologies are now being investigated for their potential to detect vulnerable plaque before rupture or to study how plaques develop and rupture.

This is believed to be the first documentation that the inflammatory cells, macrophages, can be detected in human atherosclerotic plaque using TR-LIFS. In a study of plaques collected from 34 patients undergoing surgical removal of carotid plaque, with 150 plaque areas analyzed, the TR-LIFS technique has been able to distinguish plaque found in inflamed areas from more stable plaque with a high degree of sensitivity and specificity.

Experiments are now being conducted on plaque that exists in patients' blood vessels, both before and after it is removed during a surgical procedure called endarterectomy. Results found with the spectroscopic technique are then compared to those found when the specimens are later analyzed in the pathology laboratory.

"Right now, the goal of our research project is to define how well the TR-LIFS technique can detect the features of plaque vulnerability. But our objective is to develop a minimally invasive, intravascular probe that will monitor plaque over time
'"/>

Contact: Sandy Van
sandy@prpacific.com
1-800-880-2397
Cedars-Sinai Medical Center
27-May-2005


Page: 1 2 3 4 5

Related medicine news :

1. Fluorescence diffuse optical tomography provides high contrast, 3-D look at breast cancer
2. Chinese children with hearing devices benefit from new speech test
3. Miniature implanted devices could treat epilepsy, glaucoma
4. Home health care devices focus of FDA Conference at UH
5. Innovative device to treat brain cancer shows promise in early studies
6. New device for stroke patients improves walking
7. UPMC begins study of heart support device as a bridge to transplantation
8. Smokeless cannabis delivery device efficient and less toxic
9. Spanish project AmIVital creates intelligent communication devices for elderly and disabled people
10. Implant device effectively maintains heart function for transplant-listed patients
11. New device could revolutionize eye disease diagnosis -- creating eye maps on the high street

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/13/2018)... ... November 13, 2018 , ... Trumpet Behavioral Health Opens ... Spectrum Disorder. , Trumpet Behavioral Health (“Trumpet”) is pleased to announce the opening ... , Austin, TX; Cincinnati, OH; Columbus, OH; Dallas, TX; Fort Worth, TX; Long ...
(Date:11/13/2018)... ... November 13, 2018 , ... 2018 was a big year for ... a lot for marketers to prepare for in the new year. , Perhaps ... of AI. Most notably, AI is having a major effect on how users interact ...
(Date:11/13/2018)... ... November 13, 2018 , ... Nearly 8 in 10 (78%) adults in the ... of women’s health care, according to a new telephone survey of more than 1,000 ... that more open discussion regarding the full range of methods and health benefits would ...
(Date:11/13/2018)... ... ... Health iPASS today announced it has topped off its $7.2 million Series ... technology-focused venture capital fund led by Nigel Morris, co-founder of CapitalOne. The investment from ... non-recourse guarantee of patient payments to medical providers who are suffering from the rise ...
(Date:11/13/2018)... ... , ... World Vasectomy Day is an annual celebration of responsible men, promoting ... in the event each year. The best way to demonstrate the ease of the ... man questions about his experience in real time. This year, WVD will be streaming ...
Breaking Medicine News(10 mins):
(Date:11/13/2018)... ... November 13, 2018 , ... Digestive Health ... , Who can resist the temptations of sweet, rich, creamy taste delights like ... Almost no one! Unfortunately, these continuous yummy food enticements can leave us with ...
(Date:11/13/2018)... ... ... Prevent Blindness , the nation’s oldest volunteer eye health and safety organization, is ... in Vision and Public Health . The Award recognizes an individual, team, or organization ... and eye health at a community, state, national, and/or international level. , The ...
(Date:11/13/2018)... ... 13, 2018 , ... Through its Microbiome Grant Initiative ... study design, planning, sample collection, and analysis to a team of cancer researchers ... of Clinical Medicine, to compare the gut microbiome in individuals with MM, individuals ...
Breaking Medicine Technology:
Cached News: