HOME >> MEDICINE >> NEWS
Folic acid supplementation lowers stroke risk

Folic acid supplementation can reduce the risk of stroke by 18% or more, conclude authors of an Article published in this week's edition of The Lancet.

But the authors and an accompanying comment caution that there remains controversy as to whether folic acid supplementation can lead to improved outcomes for other cardiovascular conditions.

Professor Xiaobin Wang, Children's Memorial Hospital and Children's Memorial Research Center, Northwestern University Feinberg School of Medicine, Chicago, USA, and colleagues did a meta-analysis (a study combining previous trials) of eight trials of folic acid that had stroke reported as one of the endpoints.

Folic acid supplementation lowers the concentrations homocysteine in the blood. High amounts of homocysteine in the blood are thought to increase the risk of stroke, as well as that of cardiovascular disease and deep vein thrombosis.

They found folic acid supplementation reduced the relative risk of stroke by an average of 18 per cent. In subgroup analyses, an even greater reduction of risk was seen when the treatment lasted over 36 months (29% less risk); if it reduced the concentration of homocysteine in the blood by more than 20% (23% less risk); or if the patient had no previous history of stroke (25% less risk).

The study also found that in areas that did not already have supplementation through fortified or partly fortified grain, folic acid supplementation decreased the risk of stroke by 25%.

The authors conclude: "Our meta-analysis provides coherent evidence that folic acid supplementation can significantly reduce the risk of stroke in primary prevention."

But they caution: "To efficiently assess the efficacy and causality of folic acid supplementation on stroke, future clinical trials should be done in regions without grain fortification, with a longer period of follow-up (4 years or longer), and among individuals without a history of stroke.<
'"/>

Contact: Professor Xiaobin Wang
XBWang@childrensmemorial.org
312-573-7738
Lancet
31-May-2007


Page: 1 2

Related medicine news :

1. Folic acid supplements do not appear to reduce risk of colorectal tumors
2. Folic acid supplementation does not appear to reduce risk of cardiovascular diseases
3. Calcium plus vitamin-D supplementation does an older body good
4. Hydrocortisone supplementation improves ventilator weaning
5. Global guidelines for iron and folic acid supplementation in children should be revised
6. Vitamin D supplementation during pregnancy could reduce osteoporosis in children
7. Vitamin E supplementation shows no overall benefit for major cardiovascular events or cancer
8. Exercise lowers insulin in breast cancer survivors
9. Moderate drinking lowers womens risk of heart attack
10. Biofeedback on abnormal mechanics lowers risk for stress fractures, pain under kneecap
11. Sword swallowers more likely to be injured when distracted or swallowing unusual swords

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/17/2019)... ... ... A clinical article reviewing the long-term performance of the latest structured breast implant technology ... Meeting 2019 in San Diego last month. The article, titled “IDEAL IMPLANT Structured Breast ... Robert A. Hardesty, M.D., and Gregg M. Anigian, M.D., and was published in the ...
(Date:10/15/2019)... Va. (PRWEB) , ... October 15, 2019 , ... ... Complying with FDA’s Most Recent IFU Guidance , **An FDAnews Webinar**, Tuesday, October ... recent Instructions for Use (IFU) guidance have on new drug applications and biologics ...
(Date:10/11/2019)... ... October 11, 2019 , ... Only 6% of orthopedic ... of them, as well as a female physician leading the sports medicine program. These ... girls who want to succeed in traditionally male-oriented fields. , Orthopedic medicine ...
(Date:10/10/2019)... ... October 10, 2019 , ... ... and information technology (IT) services for the healthcare industry, has completed the first ... Authority (PHA) of the Commonwealth of The Bahamas towards a fully integrated health ...
(Date:10/8/2019)... ... 2019 , ... What unique insights can three former Surgeons General of the ... the nation? That question will be answered at ICAA 2019: Shaping the Future of ... event will take place October 10-12, 2019, at the Gaylord Palms Resort and Convention ...
Breaking Medicine News(10 mins):
(Date:10/10/2019)... ... October 10, 2019 , ... ... Cocktail Reception on Thursday, September 26, at the Westchester Country Club in Rye. ... unwavering support of the organization and its mission. , “In Celebration” featured live ...
(Date:10/8/2019)... ... ... “When Seconds Count: Reports From an Emergency Medical Helicopter Pilot”: a powerful read ... the real stories of the EMS flight crew. “When Seconds Count: Reports From an ... EMS helicopter pilot. He has been a pilot in the HEMS industry for twelve ...
(Date:10/8/2019)... ... October 08, 2019 , ... ... advanced dental implant seminar to enhance his skill and knowledge of dental implant ... Dentistry Continuum™ is a four-part series of classes that combines in-depth lectures with ...
Breaking Medicine Technology:
Cached News: