HOME >> MEDICINE >> NEWS
Fosrenol data show evidence of trends towards improved bone formation in CKD stage 5 patients

San Diego, Calif. (November 17, 2006) Treatment with the phosphate binder FOSRENOL(R) (lanthanum carbonate) was associated with slight improvements in bone formation in chronic kidney disease (CKD) Stage 5 patients with hyperphosphatemia (high phosphorus levels in the blood), according to long-term (two-year) data presented at the American Society of Nephrology (ASN) meeting. Additional studies presented at ASN document the efficacy and safety of the reformulated and higher-dose FOSRENOL tablets.

Of the approximately 20 million Americans who have some form of kidney disease, more than 530,000 have developed CKD Stage 5. Even with dialysis and a low-phosphorus diet, most CKD Stage 5 patients in the United States will develop hyperphosphatemia. Without effective treatment, hyperphosphatemia may lead to renal osteodystrophy, a collection of bone diseases characterized by bone pain, brittle bones, skeletal deformities and fractures.

"Renal osteodystrophy develops early during chronic kidney disease, so by the time many patients reach dialysis, they may have painful and debilitating bone conditions. Treating hyperphosphatemia through diet and an effective phosphate binder can help patients maintain bone health while on dialysis," explained Hartmut H. Malluche, M.D., study author and chief of Nephrology, Bone and Mineral Metabolism in the Department of Internal Medicine at the University of Kentucky College of Medicine. "Our study showed that FOSRENOL treatment was associated with increased bone formation in participants and that there were no signs of bone abnormalities, such as progressive evolution of mineralization defects or decreases in bone turnover."

This planned sub-study of a large Phase III clinical trial evaluated potential differences between standard therapy and lanthanum carbonate on the evolution of abnormalities of bone turnover, bone balance and mineralization in patients with CKD Stage 5. Investigators used bone bi
'"/>

Contact: Carrie Fernandez
212-601-8336
Porter Novelli
17-Nov-2006


Page: 1 2 3 4 5

Related medicine news :

1. Majority of herb users dont follow evidence-based indications, researchers find
2. No evidence older women generate new eggs
3. Opportunistic chlamydia screening not underpinned by sound evidence
4. Drug safety recommendations lack scientific evidence
5. Study links attempted suicide with genetic evidence identified in previous suicide research
6. Mayo Clinic researchers find evidence for traumatic cause of carpal tunnel syndrome
7. ACPs electronic medical resource ranked no. 1 evidence-based tool by MLAs South Central Chapter
8. New evidence finds an association between periodontal disease and stroke
9. How low should we go? Researchers find no clear evidence for ultra-low cholesterol targets
10. First evidence that musical training affects brain development in young children
11. Studies provide new evidence on risks associated with Cox-2 inhibitors and NSAIDs

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/25/2017)... (PRWEB) , ... September 25, 2017 , ... The Asset ... solution. It is as simple as scanning the bar code of the product ... sent to a secure internet cloud where violations are automatically generated and exception alerts ...
(Date:9/25/2017)... ... September 25, 2017 , ... Ron ... an option to senior, upper-level executives speaking at a business luncheon today, "It ... high-level executive is an asset to be fully realized and activated by the ...
(Date:9/25/2017)... (PRWEB) , ... September 25, 2017 , ... Earlypicker is ... for a one-stop shop for the hottest Korean cosmetics and fashion trends sweeping the ... a company that’s already well-known for the great offerings that allow Koreans everywhere to ...
(Date:9/25/2017)... ... September 25, 2017 , ... “Renew Refresh Restore Reward”: ... Refresh Restore Reward” is the creation of published author, Deborah Freeman, cofounded the Free ... , “When we returned to our cars, my sister-in-law invited us to come over ...
(Date:9/25/2017)... ... ... “Grandpa's Visit”: a tender and relatable tale of several generations realizing that they ... creation of published author, Beverly Brumfield, gifted writer and dedicated author. , ... She shares, “Mr. Rice is struggling to keep up with the fast-moving and ever-changing ...
Breaking Medicine News(10 mins):
(Date:9/7/2017)...  Eli Lilly and Company (NYSE: ... to more efficiently focus resources on developing new ... workforce reductions, including those from a U.S. voluntary ... 3,500 positions. With the streamlining ... approximately $500 million that will begin to be ...
(Date:9/7/2017)... 7, 2017 Caris Life Sciences, a ... the promise of precision medicine, today announced results ... of its molecular profiling approach in guiding therapeutic ... profiling plus (CGP+) with Caris Molecular Intelligence ® ... a molecular level, leading to more therapeutic options ...
(Date:9/7/2017)... 2017  Zimmer Biomet Holdings, Inc. (NYSE and SIX: ... that it will be participating in the Morgan Stanley ... Grand Hyatt hotel in New York.  Zimmer Biomet will ... Eastern Time. A live webcast of the ... website at http://investor.zimmerbiomet.com .   ...
Breaking Medicine Technology:
Cached News: