HOME >> MEDICINE >> NEWS
Fosrenol data show evidence of trends towards improved bone formation in CKD stage 5 patients

San Diego, Calif. (November 17, 2006) Treatment with the phosphate binder FOSRENOL(R) (lanthanum carbonate) was associated with slight improvements in bone formation in chronic kidney disease (CKD) Stage 5 patients with hyperphosphatemia (high phosphorus levels in the blood), according to long-term (two-year) data presented at the American Society of Nephrology (ASN) meeting. Additional studies presented at ASN document the efficacy and safety of the reformulated and higher-dose FOSRENOL tablets.

Of the approximately 20 million Americans who have some form of kidney disease, more than 530,000 have developed CKD Stage 5. Even with dialysis and a low-phosphorus diet, most CKD Stage 5 patients in the United States will develop hyperphosphatemia. Without effective treatment, hyperphosphatemia may lead to renal osteodystrophy, a collection of bone diseases characterized by bone pain, brittle bones, skeletal deformities and fractures.

"Renal osteodystrophy develops early during chronic kidney disease, so by the time many patients reach dialysis, they may have painful and debilitating bone conditions. Treating hyperphosphatemia through diet and an effective phosphate binder can help patients maintain bone health while on dialysis," explained Hartmut H. Malluche, M.D., study author and chief of Nephrology, Bone and Mineral Metabolism in the Department of Internal Medicine at the University of Kentucky College of Medicine. "Our study showed that FOSRENOL treatment was associated with increased bone formation in participants and that there were no signs of bone abnormalities, such as progressive evolution of mineralization defects or decreases in bone turnover."

This planned sub-study of a large Phase III clinical trial evaluated potential differences between standard therapy and lanthanum carbonate on the evolution of abnormalities of bone turnover, bone balance and mineralization in patients with CKD Stage 5. Investigators used bone bi
'"/>

Contact: Carrie Fernandez
212-601-8336
Porter Novelli
17-Nov-2006


Page: 1 2 3 4 5

Related medicine news :

1. Majority of herb users dont follow evidence-based indications, researchers find
2. No evidence older women generate new eggs
3. Opportunistic chlamydia screening not underpinned by sound evidence
4. Drug safety recommendations lack scientific evidence
5. Study links attempted suicide with genetic evidence identified in previous suicide research
6. Mayo Clinic researchers find evidence for traumatic cause of carpal tunnel syndrome
7. ACPs electronic medical resource ranked no. 1 evidence-based tool by MLAs South Central Chapter
8. New evidence finds an association between periodontal disease and stroke
9. How low should we go? Researchers find no clear evidence for ultra-low cholesterol targets
10. First evidence that musical training affects brain development in young children
11. Studies provide new evidence on risks associated with Cox-2 inhibitors and NSAIDs

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... , ... October 13, 2017 , ... “America On The ... identity. “America On The Brink” is the creation of published author, William Nowers. ... great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed a ... and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been ... standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the ... to develop to enable prevention of a major side effect of chemotherapy in ... in pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... On Saturday, ... a treadmill relay – Miles by Moonlight to raise money for the American Heart ... or more. , Teams will work together to keep their treadmills moving for ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... latest in wound care advancements to physician colleagues, skilled nursing facility medical directors ... "Navigating the Treacherous Waters of Wound Care." , "At many of these conferences ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  Caris Life Sciences ® ... fulfilling the promise of precision medicine, today announced that ... Caris, Precision Oncology Alliance™ (POA) as its 17 th ... the St. Jude Crosson Cancer Institute will help develop ... use of tumor profiling, making cancer treatment more precise ...
(Date:10/10/2017)... 2017   West Pharmaceutical Services, Inc. (NYSE: ... drug administration, today shared the results of a study ... the intradermal administration of polio vaccines. The study results ... May 2017 by Dr. Ondrej Mach , Clinical ... Organization (WHO), and recently published in the journal ...
(Date:10/4/2017)... the Centers for Disease Control and Prevention (CDC), influenza vaccination should ... helping communities across Massachusetts , Connecticut ... shots through the end of the month. *Some exclusions apply ... ... is by the end of October, according to the Centers for Disease ...
Breaking Medicine Technology:
Cached News: