HOME >> MEDICINE >> NEWS
Free antiretroviral therapy key to success of AIDS treatment in developing countries

HIV-infected patients starting highly active antiretroviral therapy (HAART) in developing countries have increased mortality rates in the first months on therapy compared with those in developed countries, according to a paper in this week's issue of The Lancet. The authors state that early diagnosis and assessment of treatment eligibility, coupled with free provision of HAART, might reduce this excess mortality.

HAART has substantially improved the prognosis of HIV-infected patients who have access to these drugs. HAART is being scaled up in developing countries but several factors could limit the effectiveness of the therapy in resource-poor settings.

In this study the researchers compared the ART-LINC Collaboration--a network of 18 HAART programmes in Africa, Asia, and South America--with a similar network of 12 HAART programmes in Europe and North America. They found that mortality was higher in low-income settings than in high-income settings. Patients in low-income countries had lower CD4 cell counts (indicating an increased risk of infection) and more advanced clinical disease when they started treatment. However, the authors state that this only partly explains the higher mortality. They believe accompanying illnesses (comorbidities) such as tuberculosis that are present in many low-income settings may have increased mortality. They also found that the provision of treatment free of charge in low-income settings was strongly associated with lower mortality.

Author Dr Matthias Egger (University of Berne, Switzerland) concludes: "Antiretroviral therapy is feasible and effective in low income settings, but, compared with industrialized countries, mortality is high in the first months. Eligibility for antiretroviral treatment and the need for treatment of tuberculosis should be determined earlier, and HAART should be started before serious comorbidities develop."

In an accompanying Editorial, The Lancet comments: "The start of th
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
9-Mar-2006


Page: 1 2

Related medicine news :

1. Study shows interruption of antiretroviral therapy increases risk of disease and death
2. No advantage for four-drug antiretroviral regimen vs. three-drug for initial treatment of HIV-1
3. Sub-Saharan Africans with HIV may achieve favorable levels of antiretroviral therapy adherence
4. Saving antiretroviral treatment in long-term HIV-positive patients
5. Access to antiretrovirals unlikely to reduce HIV infection rates
6. Study sets new gold standard for initial antiretroviral treatment of HIV infection
7. International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy
8. HIV mortality in India drops with introduction of generic antiretroviral therapy
9. Highly active antiretrovirals for HIV can substantially reduce rates of AIDS
10. Chemotherapy with bevacizumab increases risk of blood clots in arteries
11. Nonsmall cell lung cancer -- chemotherapy before surgery appears better than surgery alone

Post Your Comments:
(Date:7/30/2014)... (PRWEB) July 30, 2014 The San Diego ... Helbock A.P.C. are announcing that they are now offering free ... effects of asbestos exposure. , “Symptoms of asbestos exposure ... to the toxin 30 plus years ago may just now ... of The Law Office of Melinda J. Helbock A.P.C. “We ...
(Date:7/29/2014)... July 30, 2014 VisitandCare.com ... have been added to the company’s exclusive network to ... out of joint efforts — as top fertility clinics ... to offer affordable, state-of-the-art, and successful IVF treatments. , ... with a comprehensive study by professionals at VisitandCare.com. The ...
(Date:7/29/2014)... July 29, 2014 1Heart Caregiver ... communities with focus on Brain Fitness Education brings ... Ventura. Brain Fitness Program Director Tee Barr delivered ... Memory Care unit and the Assisted Living section ... Life Enrichment Director Christy Rozsa and Aegis Life ...
(Date:7/29/2014)... say they have discovered a chemical alteration in a ... confirmed in larger studies, could give doctors a simple ... attempting suicide. , The discovery, described online in ... in a gene involved in the function of the ... in turning what might otherwise be an unremarkable reaction ...
(Date:7/29/2014)... Denver, Colorado (PRWEB) July 29, 2014 Diabetes ... this disease is developed, blood sugar levels are increased, while ... the hormone produced by the pancreas and which is needed ... extremely difficult to overcome and can be very dangerous, as ... , To learn more about this disorder and read ...
Breaking Medicine News(10 mins):Health News:The Law Office of Melinda J. Helbock A.P.C. Offers Case Evaluations for Possible Asbestos Claims 2Health News:Top European Fertility Clinics Join VisitandCare.com 2Health News:Top European Fertility Clinics Join VisitandCare.com 3Health News:Top European Fertility Clinics Join VisitandCare.com 4Health News:1Heart Caregiver Services Conducts Brain Fitness Education and Brings Tee Barr to Aegis Ventura 2Health News:1Heart Caregiver Services Conducts Brain Fitness Education and Brings Tee Barr to Aegis Ventura 3Health News:1Heart Caregiver Services Conducts Brain Fitness Education and Brings Tee Barr to Aegis Ventura 4Health News:A blood test for suicide? 2Health News:A blood test for suicide? 3Health News:Reverse Your Diabetes Today Review Exposes Matt Traverso’s New eBook 2
(Date:7/29/2014)... , July 29, 2014 /PRNewswire-iReach/ -- MHG ... provider, has launched its Medical Equipment and ...  These services are tailored to the cruise industry,s ... prompted industry operators to propose that they should ... Medical,s new program is intended to create standardized ...
(Date:7/29/2014)... York , July 29, 2014 ... Transparency Market Research "Orthopedic Trauma Fixation Devices Market - ... 2014 - 2020", the global orthopedic trauma fixation devices ... and is expected to grow at a CAGR of ... value of USD 9.3 billion in 2020. ...
(Date:7/29/2014)... TORONTO , July 29, ... ESAQ), an emerging pharmaceutical company exploring drug ... novel formulations and alternative dosage forms of ... its pharmaceutical development implementing its sub-micron platform technology.  ... drugs that will address indications in diabetes ...
Breaking Medicine Technology:MHG Medical Management Services Aims to Change Cruise Industry Standard With New Equipment Maintenance Program 2Orthopedic Trauma Fixation Devices Market is Expected to Reach USD 9.3 Billion Globally in 2020: Transparency Market Research 2Orthopedic Trauma Fixation Devices Market is Expected to Reach USD 9.3 Billion Globally in 2020: Transparency Market Research 3Orthopedic Trauma Fixation Devices Market is Expected to Reach USD 9.3 Billion Globally in 2020: Transparency Market Research 4EastGate Acquisitions Announces Expansion of its Pharmaceutical Developments Implementing its Sub-Micron Platform Technology 2EastGate Acquisitions Announces Expansion of its Pharmaceutical Developments Implementing its Sub-Micron Platform Technology 3EastGate Acquisitions Announces Expansion of its Pharmaceutical Developments Implementing its Sub-Micron Platform Technology 4
Cached News: