Garlic does not appear to lower cholesterol levels

Three forms of garlicincluding raw garlic and two types of commercial garlic supplementsdid not significantly reduce low-density lipoprotein (LDL or "bad") cholesterol during a six-month trial, according to results published in the February 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

"Garlic supplements, many of which seek to package the benefits of raw garlic in more palatable forms, are promoted as cholesterol-lowering agents and are among the top-selling herbal supplements," the authors write as background information in the article. Crushing garlic triggers the formation of a compound known as allicin, which has been shown to prevent the formation of cholesterol in the laboratory. However, clinical trials on garlic as a cholesterol-lowering agent in humans have been inconsistent.

Christopher D. Gardner, Ph.D., Stanford University Medical School, Calif., and colleagues enrolled 192 adults age 30 to 65 who had moderately high LDL levels (130 to 190 milligrams per deciliter) beginning in November 2002. Forty-nine participants were randomly assigned to receive raw garlic, 47 to take a powdered garlic supplement, 48 to take an aged garlic supplement and 48 to take placebo. The amount of garlic consumed in the three garlic groups was the equivalent of an average-sized garlic clove each day, six days per week. Fasting blood cholesterol levels were assessed monthly, and the chemical composition of the supplements was checked regularly.

A total of 169 adults completed the study, which continued through June 2005. "Retention was 87 percent to 90 percent in all four treatment arms, and the chemical stability of study materials was high throughout the trial," the authors write. "There were no statistically significant effects of the three forms of garlic on LDL cholesterol concentrations." Levels of other types of cholesterolincluding high-density lipoprotein (HDL or "good" cholesterol), triglyceride

Contact: Susan Ipaktchian
JAMA and Archives Journals

Page: 1 2

Related medicine news :

1. Garlic hope in infection fight
2. DNA vaccine against multiple sclerosis appears safe, potentially beneficial
3. Some women benefit more from exercise when emphasis is on health, not appearance
4. ADHD appears to be associated with depressed dopamine activity in the brain
5. Nonsmall cell lung cancer -- chemotherapy before surgery appears better than surgery alone
6. Folic acid supplements do not appear to reduce risk of colorectal tumors
7. Off-label and untested use of drug-coated stents appears widespread
8. Experimental flu vaccine appears promising in early tests
9. Jefferson scientists find that plavix appears to be safe during and after heart bypass
10. Mental illnesses appear common among veterans returning from Iraq and Afghanistan
11. Injection of skin filler material appears to stimulate collagen production

Post Your Comments:

(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. ... The attorneys chosen by their peers for this recognition are considered among the top ... Shareholders received special honors as members of this year’s Legal Elite Hall of Fame: ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening ... Talker Award, an essay contest in which patients and their families pay tribute to ... at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute ... Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s newest ... world, and the most handsome men, look naturally attractive. Plastic surgery should be ...
(Date:6/24/2016)... ... 2016 , ... Strategic Capital Partners, LLC (SCP) in concert ... capital for emerging technology companies. SCP has delivered investment events and professional ... than a million dollars of capital investment for five companies. The ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that it ... (procalcitonin) assay as a dedicated testing solution for people ... Roche is the first IVD company in the U.S ... assessment and management. PCT is a sepsis-specific ... blood can aid clinicians in assessing the risk of ...
(Date:6/23/2016)... June 23, 2016 , , ... July 7, 2016 , , , , LOCATION: , , ... , , , EXPERT PANELISTS:  , , , Frost & ... Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, ... The global pharmaceutical industry is witnessing an exceptional era. Several new ...
(Date:6/23/2016)... , June 23, 2016 The vast ... an outpatient dialysis facility.  Treatments are usually 3 times ... hours per visit, including travel time, equipment preparation and ... patient, but especially grueling for patients who are elderly ... a skilled nursing and rehabilitation centers for some duration ...
Breaking Medicine Technology:
Cached News: