HOME >> MEDICINE >> NEWS
Genetic screening for iron blood disorder feasible in the workplace

Screening for a condition called haemochromatosis, where iron to builds up in the body, could help prevent organ damage and disease, suggests a study published online today by THE LANCET.

People who inherit two copies of a mutation in a gene called HFE are predisposed to haemochromatosis. The disorder, which affects one in 200 north Europeans, causes the body to absorb and store too much iron. If untreated, the disorder can result in liver cirrhosis, heart problems, diabetes, arthritis and chronic fatigue. Genetic screening for the condition is controversial because not everyone who has the mutation develops the disorder, insurers and employers may discriminate against carriers of the mutation, and screening may cause anxiety.

In the study Katie Allen (Murdoch Children's Research Institute, Melbourne Australia) and colleagues took cheek brush samples from 11, 800 adults, in their workplaces in Australia. They screened the samples for the HFE mutation and identified 47 participants who had two copies of the mutation and 1338 individuals who had one copy of the mutation. 46 of the 47 newly identified carriers took steps to prevent or treat iron accumulation. Almost all the participants were pleased they had the test and there was no increase in anxiety in the individuals who had two copies of the gene. All individuals who had the gene mutation and sought insurance had their policies underwritten at normal standard rates. This was due to an agreement the authors achieved with the Australian insurance industry to ensure mutation carriers were not discriminated against.

Dr Allen concludes: "Health economic considerations are vital to decisions regarding screening programmes. An economic analysis of this programme is currently ongoing. If genetic screening is shown to be cost-effective, it should be implemented since hereditary haemochromatosis can be prevented by simple measures and, as shown in our study, the risks of such screening are very low
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
25-Apr-2005


Page: 1 2

Related medicine news :

1. Genetic variations may predispose some men to suicidal thoughts during treatment for depression
2. Genetic mutations identified for type of gastric cancer
3. Genetic marker linked to aggressive prostate cancer
4. Genetic markers in surrounding tissues linked to breast cancer tumor grade, presence of metastases
5. Genetic pathways to curable and incurable forms of pancreatic cancer identified
6. Genetically modified cells attack tumors
7. Genetic variation linked to age-related macular degeneration
8. Genetic insights may explain retinal growth, eye cancer
9. Genetic perversity: Smoking & gene avert Parkinsons
10. Genetics plays role in relapse of illicit drug-seeking behavior
11. Genetic mutation linked to West Nile virus infection

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps ... provides a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... York, NY (PRWEB) , ... October 13, 2017 , ... ... influential people in business to advocate for action towards gender equality at their inaugural ... views from around the globe, and reached a social audience of over 3 million. ...
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... received FDA 510(k) clearance in May 2017 for its highly anticipated ... for endoscopy environments. An innovative secondary monitor solution, ZeroWire Mobile ... the improvement of patient outcomes, procedural efficiency, and the lowering of ... ... By ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare product ... training aide "cprCUBE" on Kickstarter. The device will educate ... cardiac arrests with better efficiency compared to the dated ... real-time feedback on efficacy of the compression for a ... has a goal to raise $5,000. ...
Breaking Medicine Technology:
Cached News: