HOME >> MEDICINE >> NEWS
Genetic screening for iron blood disorder feasible in the workplace

Screening for a condition called haemochromatosis, where iron to builds up in the body, could help prevent organ damage and disease, suggests a study published online today by THE LANCET.

People who inherit two copies of a mutation in a gene called HFE are predisposed to haemochromatosis. The disorder, which affects one in 200 north Europeans, causes the body to absorb and store too much iron. If untreated, the disorder can result in liver cirrhosis, heart problems, diabetes, arthritis and chronic fatigue. Genetic screening for the condition is controversial because not everyone who has the mutation develops the disorder, insurers and employers may discriminate against carriers of the mutation, and screening may cause anxiety.

In the study Katie Allen (Murdoch Children's Research Institute, Melbourne Australia) and colleagues took cheek brush samples from 11, 800 adults, in their workplaces in Australia. They screened the samples for the HFE mutation and identified 47 participants who had two copies of the mutation and 1338 individuals who had one copy of the mutation. 46 of the 47 newly identified carriers took steps to prevent or treat iron accumulation. Almost all the participants were pleased they had the test and there was no increase in anxiety in the individuals who had two copies of the gene. All individuals who had the gene mutation and sought insurance had their policies underwritten at normal standard rates. This was due to an agreement the authors achieved with the Australian insurance industry to ensure mutation carriers were not discriminated against.

Dr Allen concludes: "Health economic considerations are vital to decisions regarding screening programmes. An economic analysis of this programme is currently ongoing. If genetic screening is shown to be cost-effective, it should be implemented since hereditary haemochromatosis can be prevented by simple measures and, as shown in our study, the risks of such screening are very low
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
25-Apr-2005


Page: 1 2

Related medicine news :

1. Genetic variations may predispose some men to suicidal thoughts during treatment for depression
2. Genetic mutations identified for type of gastric cancer
3. Genetic marker linked to aggressive prostate cancer
4. Genetic markers in surrounding tissues linked to breast cancer tumor grade, presence of metastases
5. Genetic pathways to curable and incurable forms of pancreatic cancer identified
6. Genetically modified cells attack tumors
7. Genetic variation linked to age-related macular degeneration
8. Genetic insights may explain retinal growth, eye cancer
9. Genetic perversity: Smoking & gene avert Parkinsons
10. Genetics plays role in relapse of illicit drug-seeking behavior
11. Genetic mutation linked to West Nile virus infection

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Genetic screening for iron blood disorder feasible the workplace

(Date:10/20/2014)... 20, 2014 hc1.com today announced ... cloud solution that enables healthcare organizations of all ... healthcare-specific customer relationship management (“CRM”) solution. , Designed ... needs of the healthcare industry, the hc1 Healthcare ... and patients by combining healthcare CRM, HIPAA-compliant collaboration, ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 AttorneyOne.com, a recognized ... latest information from the FDA on Sit and Slim ... 10 not to purchase or use Sit and Slim II ... Slim II is promoted as weight loss product on various ... from the market in 2010 for safety reasons, can significantly ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 National Teen Driver ... of the American Academy of Pediatrics (Ohio AAP, http://www.ohioaap.org ... in encouraging parents of teen drivers to talk to their ... road. , Motor vehicle crashes are the leading cause of ... drivers involved in fatal crashes, and 859 (42%) of those ...
(Date:10/20/2014)... Texas (PRWEB) October 20, 2014 Houston ... to present the key elements of his innovative ... professor to plastic surgery residents and faculty at ... , where he, too, was once a medical student. ... the largest private cosmetic plastic surgery practices in Texas, ...
(Date:10/19/2014)... 2014 Dr. Babatunde Osotimehin, Executive Director ... of a ceasefire agreement that is expected to lead ... who were kidnapped from the north-eastern Nigerian town of ... long enough, and it is high time they are ... Osotimehin. , "We owe it to these girls to ...
Breaking Medicine News(10 mins):Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2Health News:FDA Advises Not to Use Sit and Slim II: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Ohio AAP Promotes National Teen Driver Safety Week 2Health News:Plastic Surgeon Patronella Presents Artistically-Inspired Tummy Tuck Method to Future Generation of Plastic Surgeons in Texas 2
(Date:10/20/2014)... de octubre de 2014  PneumRx, Inc. ( ... la pulmonología intervencional, anunció hoy la conclusión de ... meses antes de lo programado. El Estudio Clínico RENEW ... de investigación (IDE) aprobada por la FDA (Administración ... espiral de reducción de volumen pulmonar PneumRx RePneu, ...
(Date:10/20/2014)... Oct. 20, 2014 Valeritas, Inc., a leader ... patients with Type 2 diabetes, announced today that it ... Award. The award was presented October 16 th ... Columbus, Ohio . The Cardinal ... a variety of metrics specifically targeted at the importance ...
(Date:10/20/2014)... 2014 Lpath, Inc. (NASDAQ: ... therapeutics, received official notification from the European Patent Office ... patent supporting its iSONEP™ and ASONEP™ programs. ... No. 2087002, claims compositions of matter related to ... compounds, iSONEP and ASONEP. Sonepcizumab is an antibody ...
Breaking Medicine Technology:PneumRx concluye inscripción en prueba fundamental RENEW 2PneumRx concluye inscripción en prueba fundamental RENEW 3Valeritas Receives 2014 Cardinal Health Supply Chain Excellence Award 2Valeritas Receives 2014 Cardinal Health Supply Chain Excellence Award 3Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 2Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 3Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 4
Cached News: