HOME >> MEDICINE >> NEWS
Green tea extract protects against brain damage in new mouse model of HIV-related dementia

Tampa, FL (May 1, 2007) -- A compound derived from green tea greatly diminished the neurotoxicity of proteins secreted by the human immunodeficiency virus, suggesting a new approach to the prevention and treatment of HIV-associated dementia, also known as AIDS dementia complex. The disorder is the most severe form of HIV-related neuropsychiatric impairment.

University of South Florida neuroscientist Brian Giunta, MD, reported the findings May 1 at Experimental Biology 2007 in Washington, DC. His presentation was part of the scientific program of the American Society for Pharmacology and Experimental Therapeutics. The study was conducted using a new mouse model for HIV-related dementia developed by Dr. Giunta and Jun Tan, MD, PhD, director of the Neuroimmunology Laboratory at the Silver Child Development Center, USF Department of Psychiatry,

"These findings suggest that EGCG, the green tea-derived compound, may represent a new and natural compound for the prevention and treatment of this devastating disease," Dr. Giunta said.

"This is a very important finding in the prevention and treatment of HIV-related dementia, which is usually observed in the late stages of HIV disease," said Abdul S. Rao, MD, MA, DPhil, senior associate vice president for USF Health and vice dean for research and graduate affairs at the College of Medicine. "The neuroprotective effects of EGCG, the green-tea extract, may offer an alternative to existing mono or combination antiretroviral therapies that are known to have poor central nervous system penetration."

HIV-associated dementia, a debilitating cognitive, emotional, and physical disorder, affects 22 percent of HIV-infected adults and more than half of HIV-infected children. Symptoms often begin with slight changes in behavior, intellectual ability, memory, and muscle coordination. Some patients experience depression-like symptoms such as loss of appetite and motivation. Tasks requiring compl
'"/>

Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3300
University of South Florida Health
1-May-2007


Page: 1 2 3

Related medicine news :

1. Green tea holds promise as new treatment for inflammatory skin diseases
2. Green tea may protect the bladder from becoming inflamed
3. Greenberg Prize awarded to Dr. Joseph G. Hayes
4. Green tea compound suppresses factors causing cartilage, bone destruction in arthritis
5. Green tea compound may be a therapy for people with rheumatoid arthritis
6. New GreeneChip identifies multiple pathogens rapidly and accurately
7. GreeneChip -- New diagnostic tool that rapidly and accurately identifies multiple pathogens
8. Green tea and the Asian Paradox
9. ERS altimeter survey shows growth of Greenland Ice Sheet interior
10. Institute of Medicine elects Gladstone Director Warner Greene
11. Green tea ingredient prevents Alzheimers-like brain damage in mice

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/7/2016)... ... December 07, 2016 , ... When it came time to blow out his candles on ... later, the Pediatric Heart Transplant team at Joe DiMaggio Children’s Hospital surprised his ... the hospital’s 30th heart transplant recipient. , “He was playing at home, when we ...
(Date:12/7/2016)... ... December 07, 2016 , ... One of two inventors ... the securement tape is painful for her. "This is why the co-inventor and I ... she said. , They then created a prototype of the patent-pending AV-AIR, a device ...
(Date:12/7/2016)... ... December 07, 2016 , ... The ... its fully redesigned website, which launched October 17, 2016, features comprehensive information regarding ... and easy-to-navigate layout. Visitors and patients can discover the latest clinical dermatology treatments ...
(Date:12/7/2016)... ... December 07, 2016 , ... The medical profession is well aware that heart ... major study analyzing heart attacks among 138,602 people recorded a 35% higher number of ... would all agree of course–no time of year is a good time for a ...
(Date:12/7/2016)... ... 07, 2016 , ... “The Road To Restoration”: an informative and enlightening ... hour a week showing of hands. “The Road To Restoration” is the creation of ... familiar with the brass ring that you could reach out for, and grab, on ...
Breaking Medicine News(10 mins):
(Date:12/6/2016)... -- Two new disaster drones delivered telemedical packages to ... event Tuesday at John Bell Airport in ... audience including Mississippi Governor ... Law Enforcement Agencies, and the United Nations. ... Rescue Operations), was developed by Italo Subbarao , ...
(Date:12/6/2016)... With opioids commonly used for pain management for workplace ... that has led to nationwide fatalities. The synthetic opioid ... than heroin or morphine, resulting in likelihood of addiction, abuse or ... , , ... operations, Behavioral Health for HMC HealthWorks, explained the opioid drug is ...
(Date:12/6/2016)... SAN DIEGO , Dec. 6, 2016 /PRNewswire/ ... ), a clinical-stage biopharmaceutical company focused on the ... disorders, today announced that the U.S. Food and ... to VK0214 for the treatment of X-linked adrenoleukodystrophy ... receptor beta (TRß) agonist that selectively regulates the ...
Breaking Medicine Technology:
Cached News: