HOME >> MEDICINE >> NEWS
Green tea extract protects against brain damage in new mouse model of HIV-related dementia

Tampa, FL (May 1, 2007) -- A compound derived from green tea greatly diminished the neurotoxicity of proteins secreted by the human immunodeficiency virus, suggesting a new approach to the prevention and treatment of HIV-associated dementia, also known as AIDS dementia complex. The disorder is the most severe form of HIV-related neuropsychiatric impairment.

University of South Florida neuroscientist Brian Giunta, MD, reported the findings May 1 at Experimental Biology 2007 in Washington, DC. His presentation was part of the scientific program of the American Society for Pharmacology and Experimental Therapeutics. The study was conducted using a new mouse model for HIV-related dementia developed by Dr. Giunta and Jun Tan, MD, PhD, director of the Neuroimmunology Laboratory at the Silver Child Development Center, USF Department of Psychiatry,

"These findings suggest that EGCG, the green tea-derived compound, may represent a new and natural compound for the prevention and treatment of this devastating disease," Dr. Giunta said.

"This is a very important finding in the prevention and treatment of HIV-related dementia, which is usually observed in the late stages of HIV disease," said Abdul S. Rao, MD, MA, DPhil, senior associate vice president for USF Health and vice dean for research and graduate affairs at the College of Medicine. "The neuroprotective effects of EGCG, the green-tea extract, may offer an alternative to existing mono or combination antiretroviral therapies that are known to have poor central nervous system penetration."

HIV-associated dementia, a debilitating cognitive, emotional, and physical disorder, affects 22 percent of HIV-infected adults and more than half of HIV-infected children. Symptoms often begin with slight changes in behavior, intellectual ability, memory, and muscle coordination. Some patients experience depression-like symptoms such as loss of appetite and motivation. Tasks requiring compl
'"/>

Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3300
University of South Florida Health
1-May-2007


Page: 1 2 3

Related medicine news :

1. Green tea holds promise as new treatment for inflammatory skin diseases
2. Green tea may protect the bladder from becoming inflamed
3. Greenberg Prize awarded to Dr. Joseph G. Hayes
4. Green tea compound suppresses factors causing cartilage, bone destruction in arthritis
5. Green tea compound may be a therapy for people with rheumatoid arthritis
6. New GreeneChip identifies multiple pathogens rapidly and accurately
7. GreeneChip -- New diagnostic tool that rapidly and accurately identifies multiple pathogens
8. Green tea and the Asian Paradox
9. ERS altimeter survey shows growth of Greenland Ice Sheet interior
10. Institute of Medicine elects Gladstone Director Warner Greene
11. Green tea ingredient prevents Alzheimers-like brain damage in mice

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... ... announce the addition of micro-needling services in their Napa Valley office. The technique ... of Plastic Surgery Associates, Dr. Canales and Dr. Furnas, are part of only ...
(Date:2/5/2016)... ... February 05, 2016 , ... The Lymphoma Research Foundation (LRF) ... and serving the lymphoma community through a comprehensive series of education programs, outreach ... Wine Tasting Event at the La Gorce Country Club in Miami Beach on ...
(Date:2/5/2016)... ... 05, 2016 , ... Regular gym users know the routine: each January, they ... access the treadmills. It’s a predictable trend. After the excesses of November and December, ... shape by joining gyms, starting new walking or running routines, or signing up for ...
(Date:2/5/2016)... ... 2016 , ... At its annual meeting held last week, the American Parkinson ... Board of Directors. Mr. McDermott succeeds former APDA Chairman, Fred Greene. , "We are ... , APDA President and CEO. “Pat has tirelessly served APDA since 2001 when he ...
(Date:2/5/2016)... ... ... Colorize is a web theme package created exclusively for Final ... dynamic moving camera. Colorize is perfect for personal and web related videos and its ... to 5 focus points per scene, stage floor scene presets that are great for ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... , Feb. 4, 2016   Bernstein Liebhard LLP ... filed in the United States District Court for the District ... class (the "Class") consisting of all persons or entities who ... "Company") (NASDAQ: INSY ) from March 3, 2015 through ... and certain of its officers with violations of the Securities ...
(Date:2/4/2016)... 2016 Summary Breast cancer, a malignant ... most common cancer in women worldwide, accounting for 16% ... The number of women diagnosed with breast cancer has ... of deaths has declined due to earlier diagnosis and ... revolutionized in the past four decades, especially with increasing ...
(Date:2/4/2016)... International Inc. (NYSE: MTD ) today announced fourth ... , Sales in local currency increased 3% ... sales decreased 3% as currency reduced sales growth by ... diluted share as reported (EPS) were $4.44, compared with ... $4.65, an increase of 10% over the prior-year amount ...
Breaking Medicine Technology:
Cached News: