HOME >> MEDICINE >> NEWS
H5N1 threat puts human flu back in spotlight

The emergence of the avian influenza virus H5N1 that is currently devastating chicken flocks in many countries and threatening to unleash a worldwide epidemic among humans has triggered a renewed interest among scientists in studying influenza A viruses, according to investigators at St. Jude Children's Research Hospital. This renewed interest could lead to new discoveries of immune system response to viruses that could lead to better drugs and vaccines, the researchers write in a review article that appears in the May issue of Nature Immunology.

"Until recently, many immunologists were relatively uninterested in studying influenza immunity because there were already effective vaccines," said Peter Doherty, Ph.D., member of the St. Jude Department of Immunology and co-recipient of the 1996 Nobel Prize for Medicine. "The current resurgence of interest in influenza immunology reflects the threat that H5N1 could evolve into a virus that spreads easily among humans. Over the years, influenza A viruses have been one of the most important models for studying how the immune system responds to viral infections. Further study of this virus and the immune response to it will no doubt help us prepare for this latest threat."

Influenza A viruses infect a wide range of animals and cause influenza outbreaks among humans. Scientists categorize influenza A viruses according to the identity of two specific proteins on their surface, HA and NA. There are 16 known subtypes of HA (H) proteins and 9 subtypes of NA (N) proteins, which are used to name the viruses, such as H5N1. The virus uses the HA protein to attach itself to a cell it is about to infect. Newly made viruses inside infected cells use NA to escape from the cell and spread.

"Studies of influenza A led to the design of Relenza and Tamiflu, two currently available anti-flu drugs," said Paul Thomas, Ph.D., a postdoctoral fellow in the St. Jude Department of Immunology and an author of the article. "B
'"/>

Contact: Kelly Perry
media@stjude.org
901-495-3306
St. Jude Children's Research Hospital
4-May-2006


Page: 1 2 3 4

Related medicine news :

1. Global warmings threat to New York region and how to avoid severe consequences
2. Sleep deprivation can threaten competent decision-making
3. Simple classification can help define and predict limb-threatening diabetic infections
4. Rapid flu tests may reduce threat of antibiotic resistance
5. Does endurance exercise promote life-threatening changes in athletes hearts?
6. Anthrax attack posed greater potential threat than thought
7. Stranger danger threat and lack of green spaces put kids off walking
8. Mental health problems threaten the knowledge economy
9. Three molecular triggers threaten leukemia patients
10. Criminalizing HIV transmission is a threat to public health, say experts
11. Predicting an answer to the threat of flooding

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: threat puts human flu back spotlight

(Date:4/17/2014)... 2014) Two recent papers by a University ... may help scientists develop treatments or vaccines for ... encephalitis and other disease-causing flaviviruses. , Jeffrey S. ... genetics at the School of Medicine and an ... Institute, and colleagues recently published articles in the ...
(Date:4/17/2014)... 2014U.S. military personnel who served in Iraq and ... brain injury (TBI) were compared to military personnel ... reasons. Differences in measures of overall disability, cognitive ... injury are reported in an article in ... Mary Ann Liebert, Inc., publishers. The article is ...
(Date:4/17/2014)... 17, 2014-- Colic affects about one in five infants ... pediatric visits during the first several months after birth. ... was showing promise; however, the April 1, 2014 issue ... Valerie) reported on a study, "Probiotics and Infant Colic," ... reuteri for infant colic did not reduce ...
(Date:4/17/2014)... An international team led by researchers at UC ... which plays a key role in cell division, also ... is the first time the complex has been shown ... cyclin B1/Cdk1 an excellent target to control cellular energy ... research was published online today in the journal ...
(Date:4/17/2014)... these days to find a colored ribbon representing a disease. ... But what color ribbon does one think of with lung ... for many suffering from the disease, black may be the ... consisting of lung cancer patients, primarily smokers between the ages ... on the stigma often felt by these patients, the emotional ...
Breaking Medicine News(10 mins):Health News:CU researchers discover target for treating dengue fever 2Health News:Long-term effects of battle-related 'blast plus impact' concussive TBI in US military 2Health News:New study says probiotic use for infant colic is not effective in reducing symptoms 2Health News:Dual role: Key cell division proteins also power up mitochondria 2Health News:Unraveling the 'black ribbon' around lung cancer 2
(Date:1/14/2014)... Pa. , Jan. 14, 2014 Dynamic Healthcare Services, ... announced today that it acquired Progressive Home Medical Equipment, Inc. ... 7, 2014. The terms of the acquisition were not disclosed. ... equipment ("DME") company providing a wide range of sleep, mobility, ...
(Date:1/14/2014)... , a manufacturer of ergonomically designed laboratory equipment for ... Japan to sell and service the Hitachi ... will utilize its network of sales professionals throughout the ... offer assistance in application use, product benefits and features, options and ...
(Date:1/14/2014)... PORT WASHINGTON, New York , January 14, ... the leading provider of Closed System Transfer Devices (CSTD) for hazardous drugs, ... sales growth for the fourth straight year.   ... of exposure for pharmacy technicians, pharmacists, nurses and ...
Breaking Medicine Technology:Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 2Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 3NuAire announces sales and service of Hitachi Koki centrifuges in North America 2Equashield's Sales Grow by 60% in 2013 2
Cached News: