HOME >> MEDICINE >> NEWS
Having sibling with cardiovascular disease associated with higher CVD risk

Middle-aged adults who have a sibling with cardiovascular disease (CVD) have a 45 percent increased risk for CVD, a risk that is greater than that conferred by having parents with CVD, according to a study in the December 28 issue of JAMA.

Cardiovascular disease in a first-degree relative confers increased risk for CVD, but whether familial CVD is truly an independent risk factor remains controversial, according to background information in the article. Risk associated with CVD in siblings is uncertain because published estimates are largely derived from case-control studies that generally lack sibling CVD event validation. Furthermore, estimates regarding magnitude of risk associated with a history of sibling CVD vary greatly. Accurate information about familial CVD will have increasing importance in prevention and treatment of CVD in the post-genome era.

Joanne M. Murabito, M.D., Sc.M., of the Framingham Heart Study, Framingham, Mass., and colleagues conducted a study to determine whether the occurrence of a validated sibling CVD event predicted CVD events in a cohort of middle-aged adults, and examined the impact of sibling CVD over and above that of parental CVD. The researchers analyzed data from the Framingham Offspring Study, a part of the Framingham Heart Study, a population-based study initiated in 1948 with the offspring cohort initiated in 1971. Participants were members of the offspring cohort aged 30 years or older, free of CVD, and with at least 1 sibling in the study. All were followed up for eight years.

Among 973 person-examinations in those who had a sibling with CVD group (average age, 57 years) and 4,506 person-examinations in those with no sibling with CVD group (average age, 47 years), 329 CVD events occurred during follow-up. The researchers found that sibling CVD was associated with a 55 percent increased risk for incident CVD; this association persisted even after adjustment for risk factors (45 percent increased ris
'"/>

Contact: Joanne M. Murabito, M.D., Sc.M.
508-935-3461
JAMA and Archives Journals
27-Dec-2005


Page: 1 2

Related medicine news :

1. Having elevated risk factors in young adulthood raises risk of coronary calcium later on
2. Stroke risk nearly doubles for siblings of people who have had a stroke
3. Hebrew University research shows developmental problems for siblings of autistic children
4. Number of siblings predicts risk of brain tumors
5. Help for siblings of children with special needs
6. New program focuses on the sometimes neglected needs of siblings of sick children
7. Obesity adds risk of cardiovascular disease in siblings in families with a history of heart problems
8. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
9. Pot bellies linked to early signs of cardiovascular disease
10. Waist-to-hip ratio may better predict cardiovascular risk than body mass index
11. Womens mortality rates for cardiovascular disease differ widely among hospitals

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and the loss ... author, William Nowers. Captain Nowers and his wife, Millie, have six children, ten ... the Navy. Following his career as a naval aviator and carrier pilot, he ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... the demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults ... tested to meet the highest standard. , These products are also: Gluten ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... that we intend to develop to enable prevention of a major side effect ... hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, the Health ... Miles by Moonlight to raise money for the American Heart Association Heart Walk. Teams ... Teams will work together to keep their treadmills moving for 5 hours. Treadmills will ...
(Date:10/12/2017)... ... October 12, 2017 , ... Vohra Chief ... advancements to physician colleagues, skilled nursing facility medical directors and other clinicians at ... of Wound Care." , "At many of these conferences we get to educate ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... YORK , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), a ... today announced that its MyDario product is expected to appear on The ... when The Dr. Oz Show airs in your area: http://www.doctoroz.com/page/where-watch-dr-oz-show ... The nine-time Emmy award-winning, The Dr. Oz ... The ...
(Date:9/23/2017)... , Sept. 22, 2017 Janssen Biotech, Inc. ... response letter from the U.S. Food and Drug Administration ... of sirukumab for the treatment of moderately to severely ... additional clinical data are needed to further evaluate the ... severely active RA. ...
(Date:9/19/2017)... venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy that uses pulsed sound ... ... Jim Bertolina, PhD ... Tom Tefft ... device executive Josh Stopek , PhD, who has led R&D and business development teams ...
Breaking Medicine Technology:
Cached News: