HOME >> MEDICINE >> NEWS
Having sibling with cardiovascular disease associated with higher CVD risk

Middle-aged adults who have a sibling with cardiovascular disease (CVD) have a 45 percent increased risk for CVD, a risk that is greater than that conferred by having parents with CVD, according to a study in the December 28 issue of JAMA.

Cardiovascular disease in a first-degree relative confers increased risk for CVD, but whether familial CVD is truly an independent risk factor remains controversial, according to background information in the article. Risk associated with CVD in siblings is uncertain because published estimates are largely derived from case-control studies that generally lack sibling CVD event validation. Furthermore, estimates regarding magnitude of risk associated with a history of sibling CVD vary greatly. Accurate information about familial CVD will have increasing importance in prevention and treatment of CVD in the post-genome era.

Joanne M. Murabito, M.D., Sc.M., of the Framingham Heart Study, Framingham, Mass., and colleagues conducted a study to determine whether the occurrence of a validated sibling CVD event predicted CVD events in a cohort of middle-aged adults, and examined the impact of sibling CVD over and above that of parental CVD. The researchers analyzed data from the Framingham Offspring Study, a part of the Framingham Heart Study, a population-based study initiated in 1948 with the offspring cohort initiated in 1971. Participants were members of the offspring cohort aged 30 years or older, free of CVD, and with at least 1 sibling in the study. All were followed up for eight years.

Among 973 person-examinations in those who had a sibling with CVD group (average age, 57 years) and 4,506 person-examinations in those with no sibling with CVD group (average age, 47 years), 329 CVD events occurred during follow-up. The researchers found that sibling CVD was associated with a 55 percent increased risk for incident CVD; this association persisted even after adjustment for risk factors (45 percent increased ris
'"/>

Contact: Joanne M. Murabito, M.D., Sc.M.
508-935-3461
JAMA and Archives Journals
27-Dec-2005


Page: 1 2

Related medicine news :

1. Having elevated risk factors in young adulthood raises risk of coronary calcium later on
2. Stroke risk nearly doubles for siblings of people who have had a stroke
3. Hebrew University research shows developmental problems for siblings of autistic children
4. Number of siblings predicts risk of brain tumors
5. Help for siblings of children with special needs
6. New program focuses on the sometimes neglected needs of siblings of sick children
7. Obesity adds risk of cardiovascular disease in siblings in families with a history of heart problems
8. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
9. Pot bellies linked to early signs of cardiovascular disease
10. Waist-to-hip ratio may better predict cardiovascular risk than body mass index
11. Womens mortality rates for cardiovascular disease differ widely among hospitals

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... ... February 05, 2016 , ... ... stage for new clinical and scientific initiatives have all marked the last 12 ... appointed President and CEO of the nation’s oldest cancer center, Candace S. Johnson, ...
(Date:2/5/2016)... ... February 05, 2016 , ... The Muscular Dystrophy Association ... restaurants, launched the 14th annual “Appetite for a Cure” campaign on Feb. 1 ... ALS and related diseases that severely limit strength and mobility. , Now ...
(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... Looking for ... may be at the tips of your toes. Foot massage, whether administered by a ... pure comfort and relaxation. The American Board of Multiple Specialties in Podiatry ...
(Date:2/5/2016)... ... 2016 , ... After years as an active staff surgeon and having served ... Dr. Wayne Carman transitioned to chief of the Division of Plastic Surgery at what ... as chief and began a second three-year term in January of 2016. , The ...
(Date:2/5/2016)... ... February 05, 2016 , ... US Sports Camps , official operators of ... direct high-performance kids yoga training. ChildLight Yoga Studio is centrally situated in the picturesque ... , ChildLight Yoga Studio founder Lisa Flynn expresses her excitement, “We are thrilled to ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... , Feb. 5, 2016 ... addition of the "Global Obstetrics Partnering ... company profile to their offering. --> ... of the "Global Obstetrics Partnering 2010-2016: ... profile to their offering. --> ...
(Date:2/4/2016)... , Feb. 4, 2016  Edwards Lifesciences Corporation (NYSE: ... for structural heart disease and critical care monitoring, announced ... repurchase (ASR) agreement with Morgan Stanley & Co. LLC ... repurchase is part of the Company,s previously authorized program ... common stock.  --> ...
(Date:2/4/2016)... 4, 2016 Worldwide Radiology Oncology surgical ... as next generation systems provide a way to ... cancer surgery. New systems pinpoint the delivery of ... been such a problem previously, limiting the quantity ... take cancer surgery far beyond what has been ...
Breaking Medicine Technology:
Cached News: