HOME >> MEDICINE >> NEWS
Having sibling with cardiovascular disease associated with higher CVD risk

Middle-aged adults who have a sibling with cardiovascular disease (CVD) have a 45 percent increased risk for CVD, a risk that is greater than that conferred by having parents with CVD, according to a study in the December 28 issue of JAMA.

Cardiovascular disease in a first-degree relative confers increased risk for CVD, but whether familial CVD is truly an independent risk factor remains controversial, according to background information in the article. Risk associated with CVD in siblings is uncertain because published estimates are largely derived from case-control studies that generally lack sibling CVD event validation. Furthermore, estimates regarding magnitude of risk associated with a history of sibling CVD vary greatly. Accurate information about familial CVD will have increasing importance in prevention and treatment of CVD in the post-genome era.

Joanne M. Murabito, M.D., Sc.M., of the Framingham Heart Study, Framingham, Mass., and colleagues conducted a study to determine whether the occurrence of a validated sibling CVD event predicted CVD events in a cohort of middle-aged adults, and examined the impact of sibling CVD over and above that of parental CVD. The researchers analyzed data from the Framingham Offspring Study, a part of the Framingham Heart Study, a population-based study initiated in 1948 with the offspring cohort initiated in 1971. Participants were members of the offspring cohort aged 30 years or older, free of CVD, and with at least 1 sibling in the study. All were followed up for eight years.

Among 973 person-examinations in those who had a sibling with CVD group (average age, 57 years) and 4,506 person-examinations in those with no sibling with CVD group (average age, 47 years), 329 CVD events occurred during follow-up. The researchers found that sibling CVD was associated with a 55 percent increased risk for incident CVD; this association persisted even after adjustment for risk factors (45 percent increased ris
'"/>

Contact: Joanne M. Murabito, M.D., Sc.M.
508-935-3461
JAMA and Archives Journals
27-Dec-2005


Page: 1 2

Related medicine news :

1. Having elevated risk factors in young adulthood raises risk of coronary calcium later on
2. Stroke risk nearly doubles for siblings of people who have had a stroke
3. Hebrew University research shows developmental problems for siblings of autistic children
4. Number of siblings predicts risk of brain tumors
5. Help for siblings of children with special needs
6. New program focuses on the sometimes neglected needs of siblings of sick children
7. Obesity adds risk of cardiovascular disease in siblings in families with a history of heart problems
8. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
9. Pot bellies linked to early signs of cardiovascular disease
10. Waist-to-hip ratio may better predict cardiovascular risk than body mass index
11. Womens mortality rates for cardiovascular disease differ widely among hospitals

Post Your Comments:
(Date:7/31/2015)... ... July 31, 2015 , ... Recently ... know in predictive health analytics , Jvion continues to disrupt the predictive ... predictive software that targets patient and population level illness to drive prevention and ...
(Date:7/31/2015)... GA (PRWEB) , ... July 31, 2015 , ... Sculpted ... , the CoolSmooth PRO this week. Zeltiq Aesthetics released this new applicator in ... in January 2014 for treating the outer thighs. The original applicator required a ...
(Date:7/31/2015)... Meadows, IL (PRWEB) , ... July 31, 2015 ... ... ways to communicate. Rally Insurance Group, Inc. has re-branded their social media profiles ... provides a personal way for consumers to communicate, find information, share insights and ...
(Date:7/31/2015)... ... July 31, 2015 , ... Ticket Down is a reliable source of ... catch a new and refreshing show on Broadway, look no further than Hamilton. This ... Obie Award, Outer Critics Circle Award, Drama Desk Award, Lucille Lortel Award, and New ...
(Date:7/31/2015)... ... July 31, 2015 , ... Well-known for its unique pastries and ... cakes with custom designs, making life just a little bit sweeter for newlyweds. ... for each customer who orders one. , The bakery provides a full line of ...
Breaking Medicine News(10 mins):Health News:Jvion Showcased as Leader in the Predictive Analytic Market 2Health News:Cooler Coolsculpting in Atlanta: Treatments Now Twice As Fast 2Health News:Cooler Coolsculpting in Atlanta: Treatments Now Twice As Fast 3Health News:Rally Insurance Group, Inc. Connects to Customers Through Re-branded Social Media Profiles 2Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 2Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 3Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 4Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 5Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 6Health News:Cheap Hamilton Tickets at Richard Rodgers Theatre: Ticket Down Slashes Ticket Prices for Hamilton in New York City at the Richard Rodgers Theatre 7Health News:Pastry Palace of Las Vegas Announces It Is Now Offering Custom Wedding Cakes in Las Vegas 2
(Date:7/31/2015)... WOODCLIFF LAKE, N.J. and SAN ... announced today that its parent company Eisai Co., Ltd. ... Haruo Naito , "Eisai") and Halozyme Therapeutics, Inc. ... and CEO: Dr. Helen Torley , "NASDAQ: HALO") ... eribulin mesylate (brand name: Halaven ® , "eribulin") in ...
(Date:7/30/2015)... 30, 2015 Mettler-Toledo International Inc. (NYSE: ... Provided below are the highlights: , Sales ... with the prior year. Reported sales decreased 4% as ... , Net earnings per diluted share as reported ... period. Adjusted EPS was $2.80 , an increase ...
(Date:7/30/2015)... IRVINE, Calif. , July 30, 2015 /PRNewswire/ ... Novartis /Alcon executives have recently contacted the Company ... will begin as early as Monday, August 3, ... been quoted as saying that the coming electronic ... billions of dollars over the next several years.  ...
Breaking Medicine Technology:Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 2Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 3Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 4Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 5Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 6Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 2Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 3Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 4Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 5Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 6Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 7Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 8Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 9Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 10Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 11Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 12Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 13Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 14
Cached News: