HOME >> MEDICINE >> NEWS
Heparin antibodies may pose risk in heart surgery patients

WINSTON-SALEM, N.C. New research suggests that patients who develop antibodies to the anti-clotting drug heparin nearly double their risk of death or serious complication after heart surgery.

"Complications after heart surgery are typically attributed to the surgery alone," said Thomas Slaughter, M.D., co-principal investigator on the project and a professor of anesthesiology at Wake Forest University Baptist Medical Center. "Our study examined whether development of heparin antibodies before surgery poses an independent risk."

The study, which involved 466 patients scheduled to undergo either coronary artery bypass or valve replacement surgery, is reported in this month's Journal of Thoracic and Cardiovascular Surgery. Conducted by investigators at Wake Forest University Baptist and Duke University medical centers, it is the first study to convincingly demonstrate a relationship between heparin antibodies and complications after cardiac surgery.

Heparin is administered intravenously during many procedures, including kidney dialysis, heart catheterization or angioplasty, as well as during heart and vascular surgeries. Estimates suggest that nearly half of patients treated with heparin develop the antibodies, which may last for months.

The researchers theorize that in patients with heparin antibodies, subsequent treatment with heparin activates blood components that cause clotting and inflammation, increasing the risk for heart attacks, heart rhythm problems, strokes and other complications.

"While it is too early to recommend universal testing for the antibodies, our study is the most definitive evidence to date that heparin antibodies increase the risk for death and complications associated with cardiac surgery," said Slaughter.

The researchers tested heparin antibody levels in all study patients before surgery. They found that patients with the antibodies experienced a nearly twofold greater risk of death or hospi
'"/>

Contact: Karen Richardson
krchrdsn@wfubmc.edu
336-716-4453
Wake Forest University Baptist Medical Center
2-Dec-2005


Page: 1 2

Related medicine news :

1. Human antibodies protect mice from avian flu
2. Syphilis screening, lithium fights neurodegeneration, monoclonal antibodies against avian flu
3. Magnesium loss in patients given monoclonal antibodies
4. Researchers from the University of Navarra analyze new kinds of cancer-fighting antibodies
5. Mice studies illustrate potential of chimp/human antibodies to protect against smallpox
6. Polymorphism and antibodies associated with highly increased risk of rheumatoid arthritis
7. Jefferson and Delaware researchers combine tiny nanotubes and antibodies to detect cancer
8. Jefferson scientists create plant factories churning out antibodies against tumor cells
9. A broader look at cardiac CTA images often finds diseases/disorders beyond the heart
10. Drug for cluster headaches may cause heart problems
11. Reductive stress linked to heart disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ... ... show evidence that carotenoids and antioxidants derived either from the diet or from supplements ... often do ophthalmologists and optometrists in Sweden recommend the use of nutritional supplements, changes ... of AMD? A study published recently in Dove Medical Press journal, ...
(Date:6/23/2017)... New York, NY (PRWEB) , ... June 23, 2017 , ... ... prefer to watch it while others prefer to read it, and some people don't ... printed versus visual pornography. Here's what they found: , Erotic literature can give readers ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... from Sept. 18 to 20. , The two-day conference is focused on advancing ... goal of improving patients’ lives and eliminating racial breast cancer-related disparities. The conference ...
(Date:6/23/2017)... ... June 23, 2017 , ... Ross Insurance Agency ( http://www.rossinsuranceagency.com ... Emergency Management Agency’s (FEMA) recent update of flood zones, more people than ever ... Act was enacted to reflect the actual risk in flood zone areas during ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... ... assistance and financial planning services to communities in the greater Chicago metropolitan area, ... to offer assistance to underprivileged youth in Chicago. , Founded in 1897, Hephzibah ...
Breaking Medicine News(10 mins):
(Date:6/20/2017)... Inc. (NYSE: HRC), will host its fiscal third quarter 2017 ... beginning at 7:30 a.m. (CDT) / 8:30 a.m. (EDT). ... the conference call, dial (877) 304-8969 (domestic) or (631) 291-4543 ... prior to the start to allow time to connect. The ... Webcast: A simultaneous webcast of the call will be ...
(Date:6/14/2017)... 14, 2017 The Bio Supply Management Alliance ... of Fremont and the Biomedical Manufacturing Network ... in California by providing a ... and fostering workforce development. The primary focus of this ... start-ups, as well as small and mid-sized biomedical companies. ...
(Date:6/10/2017)... K. Burchfield, DPM, is recognized by Continental Who,s Who as a ... Alabama . Dr. Burchfield serves as ... over 20 years of experience, as well as expertise in the ... "The podiatry professional ... to welcome you to his practice," the company,s website states. "We ...
Breaking Medicine Technology:
Cached News: