HOME >> MEDICINE >> NEWS
Hepatitis C recurs rapidly after liver transplant

When a diseased liver is removed from a patient with Hepatitis C (HCV), serum viral levels plummet. However, after receiving a healthy liver transplant, virus levels rebound and can surpass pre-transplant levels within a few days, according to a new study published in the February 2006 issue of Liver Transplantation, the official journal of the American Association for the Study of Liver Diseases (AASLD) and the International Liver Transplantation Society (ILTS). The journal is published on behalf of the societies by John Wiley & Sons, Inc. and is available online via Wiley InterScience (http://www.interscience.wiley.com/journal/livertransplantation).

Hepatitis C is the number one reason for liver transplantation, however, the virus always recurs in the new liver. Since mathematical models have been useful in the study of the viral dynamics of HIV and hepatitis B, researchers, led by Kimberly A. Powers and Ruy M. Ribeiro of the Los Alamos National Laboratory in New Mexico, sought to use a mathematical model to quantify the liver reinfection dynamics of HCV.

The researchers, in collaboration with a surgical team lead by John McHutchison now at Duke University Medical Center, followed six HCV-infected patients who received cadaveric liver transplants. They collected blood samples before, during and after transplantation to assess changing levels of HCV RNA which was measured using reverse transcription polymerase chain reaction assay. They then plugged the data into a mathematical model, correcting for fluid balance, and analyzed the results using linear regression.

"In most patients," the authors report, "HCV RNA levels decreased rapidly during and after transplantation and subsequently began to increase reaching above pre-transplant levels in all but one patient within a few days of the procedure." They found that when the diseased liver was removed, virus level
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
2-Feb-2006


Page: 1 2

Related medicine news :

1. Hepatitis C negatively impacts HIV
2. Hepatitis B patients understanding of infection and treatment deficient
3. Hepatitis C increases risk of non-Hodgkin lymphoma
4. HIV/Hepatitis information service through the Internet
5. Liver transplants can be successful in HIV patients with Hepatitis B
6. NDRI researchers evaluate prison Hepatitis program
7. Scientists call for Hepatitis treatment of young injection drug users
8. Preventive treatment helps avoid Hepatitis B relapse during chemotherapy
9. Patients with Hepatitis C using more healthcare resources
10. Interferon with ribavirin is safe and effective for children with chronic Hepatitis C
11. Hepatitis C drug proves cost-effective in helping patients with treatment-induced anemia

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Hepatitis recurs rapidly after liver transplant

(Date:4/21/2015)... 21, 2015 The joint venture between ... is opening its first freestanding emergency room later this ... and will be licensed under Dignity Health Arizona General ... and Adeptus Health joint venture. , Tim Bricker, President ... Gilbert Medical Centers said the new facility will complement ...
(Date:4/21/2015)... April 21, 2015 Catalent (Booth ... technologies and development solutions for drugs, biologics and ... ADVASEPT™ Lock, a stopper-less, glass- and needle-free vial ... medications. Easily opened, ADVASEPT Lock attaches to a ... container closure with the security of an advanced ...
(Date:4/21/2015)... April 21, 2015 Carinsurancehints.com has released ... and explaining their impact on auto insurance prices ... increase auto insurance prices. Clients should review their insurance ... can be bought under several forms. Some of the ... , rivers can compare online rates and find the ...
(Date:4/21/2015)... This year, in recognition of IAM, the Foundation ... publish a unique awareness campaign featuring real-life patients, affected ... of May and carry the message, "Be Inspired. Use ... was chosen to encourage the general public to learn ... support our mission of educating, inspiring and connecting all ...
(Date:4/21/2015)... has released a new blog post explaining the ... , Comprehensive auto insurance is a complex policy ... limit can also be high and the premiums are ... against fire damage, vandalism, theft and from many other ... and it can help drivers find the right type ...
Breaking Medicine News(10 mins):Health News:Dignity Health and Adeptus Health to Open First Freestanding Emergency Room in Chandler, Arizona 2Health News:Dignity Health and Adeptus Health to Open First Freestanding Emergency Room in Chandler, Arizona 3Health News:Catalent Announces the Expansion of its Advanced, Aseptic, Glass-Free Injectable Platform with New ADVASEPT™ Lock Delivery Technology 2Health News:Heavily Circulated Roads Can increase Auto Insurance Costs 2Health News:May is Ichthyosis Awareness Month. Use Your Voice. 2Health News:Comprehensive Auto Insurance Is An Important But Complex Policy 2
(Date:4/21/2015)... Mont. , April 21, 2015  St. ... comes to patient care. Already following strict disinfection ... robot Tru-D SmartUVC to eliminate harmful germs, like ... influenza and norovirus that can infect patients during ... Logo - http://photos.prnewswire.com/prnh/20150420/199749LOGO ...
(Date:4/21/2015)... NEW YORK , April 21, 2015  IntelliQuit™, the world,s first smartphone breathalyzer for smokers, ... Investment Forum in New York City on Wednesday April 22.  ... ... ... Thirty percent (30%) of ...
(Date:4/21/2015)... 21, 2015  Navitas has launched Aviator, a Cloud ... of offerings for life sciences clients. Aviator supports Regulatory, ... enabling seamless flow of data across all applications and ... Navitas worked closely with Oracle to provide Argus, Life ... in the Cloud. ...
Breaking Medicine Technology:St. Vincent Healthcare Deploys Germ-Killing Robot to Prevent Infection, Protect Patients During Hospital Visits 2St. Vincent Healthcare Deploys Germ-Killing Robot to Prevent Infection, Protect Patients During Hospital Visits 3IntelliQuit World's First Smartphone Breathalyzer for Smokers to Present to American Heart Association Innovation Investment Forum 2IntelliQuit World's First Smartphone Breathalyzer for Smokers to Present to American Heart Association Innovation Investment Forum 3Navitas Launches Aviator - Cloud Based Platforms for Oracle Solutions 2Navitas Launches Aviator - Cloud Based Platforms for Oracle Solutions 3Navitas Launches Aviator - Cloud Based Platforms for Oracle Solutions 4
Cached News: