HOME >> MEDICINE >> NEWS
Hepatitis C recurs rapidly after liver transplant

When a diseased liver is removed from a patient with Hepatitis C (HCV), serum viral levels plummet. However, after receiving a healthy liver transplant, virus levels rebound and can surpass pre-transplant levels within a few days, according to a new study published in the February 2006 issue of Liver Transplantation, the official journal of the American Association for the Study of Liver Diseases (AASLD) and the International Liver Transplantation Society (ILTS). The journal is published on behalf of the societies by John Wiley & Sons, Inc. and is available online via Wiley InterScience (http://www.interscience.wiley.com/journal/livertransplantation).

Hepatitis C is the number one reason for liver transplantation, however, the virus always recurs in the new liver. Since mathematical models have been useful in the study of the viral dynamics of HIV and hepatitis B, researchers, led by Kimberly A. Powers and Ruy M. Ribeiro of the Los Alamos National Laboratory in New Mexico, sought to use a mathematical model to quantify the liver reinfection dynamics of HCV.

The researchers, in collaboration with a surgical team lead by John McHutchison now at Duke University Medical Center, followed six HCV-infected patients who received cadaveric liver transplants. They collected blood samples before, during and after transplantation to assess changing levels of HCV RNA which was measured using reverse transcription polymerase chain reaction assay. They then plugged the data into a mathematical model, correcting for fluid balance, and analyzed the results using linear regression.

"In most patients," the authors report, "HCV RNA levels decreased rapidly during and after transplantation and subsequently began to increase reaching above pre-transplant levels in all but one patient within a few days of the procedure." They found that when the diseased liver was removed, virus level
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
2-Feb-2006


Page: 1 2

Related medicine news :

1. Hepatitis C negatively impacts HIV
2. Hepatitis B patients understanding of infection and treatment deficient
3. Hepatitis C increases risk of non-Hodgkin lymphoma
4. HIV/Hepatitis information service through the Internet
5. Liver transplants can be successful in HIV patients with Hepatitis B
6. NDRI researchers evaluate prison Hepatitis program
7. Scientists call for Hepatitis treatment of young injection drug users
8. Preventive treatment helps avoid Hepatitis B relapse during chemotherapy
9. Patients with Hepatitis C using more healthcare resources
10. Interferon with ribavirin is safe and effective for children with chronic Hepatitis C
11. Hepatitis C drug proves cost-effective in helping patients with treatment-induced anemia

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Hepatitis recurs rapidly after liver transplant

(Date:7/31/2014)... 2014 Current residents at Back2Basics ... in Flagstaff, AZ, learn to kayak safely for the ... paddle strokes in preparation for next week's wilderness therapy ... that [the kayaking course] teaches [residents] to listen and ... in their early part of their sobriety," said ...
(Date:7/31/2014)... 31, 2014 Parker Waichman, LLP, a ... cases, comments that whistleblowers are a critical component of ... activities that may cause harm to consumers and may ... Whistleblower Appreciation Day. , According to a 2013 report ... Senate declared "National Whistleblower Appreciation Day" on July 30, ...
(Date:7/31/2014)... (PRWEB) July 31, 2014 To further ... like to provide the following safety information regarding leaving ... a car can have deadly consequences. Because a child’s ... than those of adults, leaving children alone in a ... injury, and even death. , Statistics of Children Left ...
(Date:7/31/2014)... Two years in the making, Becoming ... of the research behind the latest scientific findings on ... Vesanto Melina, well-respected authorities on plant-based nutrition, put forth ... and adequate for people at all stages of life, ... and pregnant or lactating women. , Well-planned is ...
(Date:7/31/2014)... 31, 2014 According to a ... , Endo International, one of several manufacturing companies that ... transvaginal claims for $830 million (in re: American Medical ... No. 2325). Melinda Helbock, Founder of The Law Office ... the settlement and is pleased to see litigation moving ...
Breaking Medicine News(10 mins):Health News:Back2Basics Substance Abuse Residents Take Kayaking Class for the First Time 2Health News:National Whistleblower Appreciation Day Declared to Ensure Recognition of Enormous Contribution to the Democracy by Whistleblowers, Parker Waichman LLP Comments 2Health News:National Whistleblower Appreciation Day Declared to Ensure Recognition of Enormous Contribution to the Democracy by Whistleblowers, Parker Waichman LLP Comments 3Health News:National Whistleblower Appreciation Day Declared to Ensure Recognition of Enormous Contribution to the Democracy by Whistleblowers, Parker Waichman LLP Comments 4Health News:The Rothenberg Law Firm LLP Teams Up with Local Philadelphia TV Stations to Promote Awareness of the Dangers of Leaving Children Unattended in a Hot Vehicle 2Health News:The Rothenberg Law Firm LLP Teams Up with Local Philadelphia TV Stations to Promote Awareness of the Dangers of Leaving Children Unattended in a Hot Vehicle 3Health News:New Book Presents Health Professionals With A Fully-Referenced, Meticulous Overview of the Research on Plant-Based Diets As A Healthy Choice 2Health News:New Book Presents Health Professionals With A Fully-Referenced, Meticulous Overview of the Research on Plant-Based Diets As A Healthy Choice 3Health News:San Diego Product Liability Firm Provides Commentary on the Latest Developments in Transvaginal Mesh Litigation 2
(Date:7/31/2014)...  UBM Medica US announces that Cancer ... presents exclusive slide shows dealing with communication in the ... care. Cancer Network, the online ... blogs, and podcasts about the latest clinical findings. Among ... , End-of-life care is challenging for even the ...
(Date:7/31/2014)... July 31, 2014 Touro University California,s College ... selected as the recipient of a $150,000 grant by ... the University to increase research and classroom space on ... technology for the study of health sciences, and will ... needs and interests of our students," said Shelley ...
(Date:7/31/2014)... 31, 2014  Cannabis Science, Inc. (OTC-QB: CBIS), ... development and related consulting, is pleased to announce ... of cannabis and European Union certified hemp varieties ... strains for development of proprietary formulations for clinical ... market for critical ailments such as cancer and ...
Breaking Medicine Technology:Cancer Network Highlights Methods Oncologists Can Use to Improve Communication 2Cancer Network Highlights Methods Oncologists Can Use to Improve Communication 3Touro University California Garners Grant From Long Foundation 2Cannabis Science Initiates Scientific Cultivation Programs to Test Multiple Strains of Cannabis to Obtain Extract Formulations for Clinical Drug Development Targeting Multiple Critical Ailments Starting with Cancer and Neurological Disorders 2
Cached News: