HOME >> MEDICINE >> NEWS
High-dose chemotherapy may improve survival for women with advanced breast cancer

In the 1990s, a number of trials found that treatment with high-dose chemotherapy after conventional chemotherapy did not improve overall survival for women with breast cancer at high-risk of spreading. However, in the latest trial, involving 403 patients with advanced breast cancer, Ulrike Nitz (University of Dusseldorf, Germany) and colleagues found that a rapidly cycled tandem high-dose chemotherapy regimen improved both event-free and overall survival when compared with conventional dose-dense chemotherapy. After 4 years event-free survival was 60% in the high-dose chemotherapy group and 44% in the conventional chemotherapy group. The corresponding overall survival was 75% and 70%, respectively.

Professor Nitz states: "Our finding of significant improvements in both event-free and overall survival for high-dose chemotherapy compared with a dose-dense conventional regimen contrasts with the results of other studies...The heterogeneous [different] designs of the trials that have been conducted to date have not allowed identification of a single promising strategy. Nevertheless, the superiority of high-dose chemotherapy in our trial suggests that this strategy remains valid for further investigation."


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
1-Dec-2005


Page: 1

Related medicine news :

1. High-dose anticlotting drug cuts heart attack, death risk in half
2. High-dose flu vaccines appear to safely boost immunity in elderly
3. High-dose vitamin C as a cancer therapy
4. Nonsmall cell lung cancer -- chemotherapy before surgery appears better than surgery alone
5. Trial shows circulating tumor cells predict how prostate cancer patients do with chemotherapy
6. Brain-boosting pill alleviates post-chemotherapy fogginess
7. Pre-operative chemotherapy does not increase survival rates for nonsmall cell lung cancer
8. Most pediatric chemotherapy mistakes reach patients
9. Growth factors given with chemotherapy associated with increased risk of blood diseases
10. Clear guidelines on oral chemotherapy needed
11. Survey reveals need for standardized oral chemotherapy prescribing practices, safeguards

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2019)... (PRWEB) , ... February 13, ... ... healthcare innovation community announced ‘ Energizing Health @ SXSW ,’ four days ... on creating opportunities for community advocates, entrepreneurs, health organizations, industry and philanthropy ...
(Date:2/13/2019)... ... February 13, 2019 , ... That wintry landscape outside the window appears, ... walkways and driveways. Then, the snow can quickly become a pain in the “back, ... to remove it,” says noted orthopaedic surgeon Kevin D. Plancher, MD, MPH , ...
(Date:2/13/2019)... , ... February 13, 2019 , ... Dr. Jig ... welcome Dr. Muizz Merchant, an exceptionally talented and knowledgeable dentist from St. ... of modern dental techniques, such as CEREC same-day dentistry, root canals and emergency treatment. ...
(Date:2/13/2019)... COSTA MESA, Calif. (PRWEB) , ... February 13, 2019 , ... ... new healthcare scholarship. Open to students who choose to pursue a medical-related course of ... best describe their passion for substance abuse disorder and mental health treatment, and how ...
(Date:2/12/2019)... Neb. (PRWEB) , ... February ... ... healthcare market research and consulting organization, devoted to helping hospital leaders, staff, ... website at http://www.prccustomresearch.com . The website now features a streamlined design, ...
Breaking Medicine News(10 mins):
(Date:2/16/2019)... (PRWEB) , ... February 15, 2019 , ... ... has joined the esteemed Haute Beauty network. , The Haute Beauty Network, well ... Bryant as a leading Face expert and our newest addition to the ...
(Date:2/14/2019)... ... February 14, 2019 , ... In ... College Emeritus Professor of Education Gregory A. Smith speaks with Christopher Saldaña, Doctoral ... Brand Ambassador programs, a new phenomenon in the marketing of educational resources to ...
(Date:2/14/2019)... ... February 14, 2019 , ... ... that focuses on developing and commercializing minimally-invasive, innovative spinal technologies, today announced ... Amplify Surgical name better emphasizes our commitment to delivering new, cutting-edge, surgical ...
Breaking Medicine Technology:
Cached News: