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High-fat, copper-rich diets associated with increased rates of cognitive decline in older adults

n rate for the high-fat consumers whose total copper intake was in the top 20 percent (greater than or equal to 1.6 milligrams per day) was equivalent to 19 more years of age," the authors write.

Other metals assessed in this study, iron and zinc, did not show any effects on cognitive decline in interaction with a high-fat diet. Previous studies have found higher levels of copper in the blood of patients with Alzheimer's disease, and medications that bind with copper to block its effects have shown promise treating patients with the condition.

"This finding of accelerated cognitive decline among persons whose diets were high in copper and saturated and trans fats must be viewed with caution," the authors conclude. "The supporting evidence on this topic is limited. The strength of the association and the potential impact on public health warrant further investigation." (Arch Neurol. 2006;63:1085-1088. Available pre-embargo to the media at http://www.jamamedia.org.)


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Contact: Mary Ann Schultz
312-942-7816
JAMA and Archives Journals
14-Aug-2006


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