HOME >> MEDICINE >> NEWS
High intake of dietary fiber not associated with reduced risk of colorectal cancer

In an analysis combining data from 13 studies, high intake of dietary fiber was not associated with reduced risk of colorectal cancer, according to a study in the December 14 issue of JAMA.

Dietary fiber has been hypothesized to reduce the risk of colorectal cancer, according to background information in the article. However, the results of numerous epidemiological studies have been inconsistent. Ecological correlation studies and many case-control studies have found an inverse association between dietary fiber intake and risk of colorectal cancer. But most prospective cohort studies have found no association between dietary fiber intake and risk of colorectal cancer or adenomas (precursors of colorectal cancer), and randomized clinical trials of dietary fiber supplementation have failed to show reductions in the recurrence of colorectal adenomas.

Yikyung Park, Sc.D., formerly of the Harvard School of Public Health, Boston, and colleagues evaluated the association between dietary fiber intake and risk of colorectal cancer by reanalyzing the primary data from 13 prospective cohort studies (Pooling Project of Prospective Studies of Diet and Cancer). The pooled analysis included 725,628 men and women who were followed-up for 6 to 20 years across studies.

During the follow-up, 8,081 colorectal cancer cases were identified. Among the studies, median (midpoint) energy-adjusted dietary fiber intake ranged from 14 to 28 g/d in men and from 13 to 24 g/d in women. The major source of dietary fiber varied across studies with cereals as a major contributor to dietary fiber intake in the European studies, and fruits and vegetables as the main sources in the North American studies.

In the age-adjusted model, dietary fiber intake was significantly associated with a 16 percent lower risk of colorectal cancer in the highest quintile compared with the lowest. This association was attenuated slightly but still remained statistically significant after
'"/>

Contact: Kevin Myron
617-432-3952
JAMA and Archives Journals
13-Dec-2005


Page: 1 2

Related medicine news :

1. Grain fiber and magnesium intake associated with lower risk for diabetes
2. Higher intake of fish and vitamin D levels linked to lower risk of age-related macular disease
3. Higher calcium and vitamin D intakes positively associated with brain lesions in older men and women
4. Comparison of 4 diet plans shows better outcomes for diet with lowest carbohydrate intake
5. Risk of spina bifida associated with choline metabolism genes, but unrelated to choline intake
6. Reduced dietary fat intake may decrease breast cancer recurrence
7. Dietary folate intake not associated with breast cancer risk
8. Low vitamin E intake during pregnancy can lead to childhood asthma
9. Coffee intake linked to lower diabetes risk
10. Moderate alcohol intake associated with better mental function in older women
11. High polyunsaturated fat and vitamin E intake may halve motor neurone disease risk

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2019)... ... August 14, 2019 , ... Inc. magazine today revealed that RKC Products, a ... the most prestigious ranking of the nation’s fastest-growing private companies. With 200% revenue growth ... in the Health sector. The list represents a unique look at the most successful ...
(Date:8/14/2019)... Nev. (PRWEB) , ... August 13, 2019 , ... In ... and the purpose of doubt in your belief systems. , “Doubt can obliterate your ... start on the path to examining them to expand your understanding and your awareness. ...
(Date:8/12/2019)... ... August 12, 2019 , ... Cryotherapy has recently been the target of negative ... However, the cause of Brown’s injury was not due to cryotherapy, but due to ... NFL teams, such as the Dallas Cowboys, the Washington Redskins, the Denver Broncos and ...
(Date:8/9/2019)... ... , ... The Los Angeles employment law lawyers at Blumenthal Nordrehaug Bhowmik ... Food Markets, Inc., failed to provide their California employees with meal and rest periods ... lawsuit, Case No. 19STCV26728, is currently pending in the Los Angeles County Superior Court ...
(Date:8/9/2019)... ... August 08, 2019 , ... Guruji Mahendra Trivedi ... affecting humanity at practical and spiritual levels. , Founder of the Trivedi ... the God of their understanding, as well as, to illuminate the path of ...
Breaking Medicine News(10 mins):
(Date:8/16/2019)... ... August 16, 2019 , ... SignatureCare Emergency ... residents of Houston, TX including Montrose, Heights, Memorial City, and Bellaire, TX. , ... in Houston Heights, is aimed at helping Houston families get their children caught ...
(Date:8/16/2019)... , ... August 16, 2019 , ... ... Innovator, Tricia Lee (Wilkins) Rolle, PharmD, PhD, has joined the company as a ... with public and private sectors and industry standards organizations to advance use of ...
(Date:8/15/2019)... ... , ... On Sunday, August 4th, volunteers from Bright Now!® Dental ... the South LA community. Six doctors joined with their dedicated support staff to provide ... more at the South Gate Day of Giving. , Over 50 individuals were ...
Breaking Medicine Technology:
Cached News: