HOME >> MEDICINE >> NEWS
High-tech spectroscopy may be used to monitor neuropsychiatric symptoms

WINSTON-SALEM, N.C. Magnetic resonance spectroscopy (MRS) may provide a noninvasive way to monitor neuropsychiatric symptoms in patients with lupus, according to results from research in mice at Wake Forest University School of Medicine.

"This study is the first to demonstrate that MRS is a feasible method to monitor neuropsychiatric symptoms in lupus," said Nilamadhab Mishra, M.D., the principal investigator, in a presentation at the American College of Rheumatology meeting in Washington.

MRS is closely related to MRI (magnetic resonance imaging), and uses strong magnetic fields and low energy radio waves to get biochemical information about the body. The test is done in an MRI machine to which a spectrometer has been attached to measure changes in metabolites, such as the levels of glutamate and glutamine.

"Because of its noninvasiveness and repeatable nature, MRS could be helpful in the drug discovery program for neuropsychiatric lupus," said Mishra, an assistant professor of rheumatology. He explained, "No definitive biomarker of neuropsychiatric lupus is available and this impedes both clinical diagnosis and drug discovery for treatment of this condition."

According to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), in neuropsychiatric lupus, there are a wide variety of associated neurological and psychiatric syndromes and cognitive problems.

NIAMS, which is supporting Mishra's work, said that about 20 percent of lupus patients have neuropsychiatric symptoms and it is one of the major causes of death among people with lupus. Systemic lupus affects an estimated 1.5 million Americans, mostly women.

In his study, Mishra is using mice that have a defective gene and spontaneously develop lupus, including lymph node swelling and increased spleen size. He is comparing these animals with control animals that do not have lupus.

His results showed "a dramatic decrease" in the ratio of two biochemi
'"/>

Contact: Robert Conn
rconn@wfubmc.edu
336-716-4587
Wake Forest University Baptist Medical Center
11-Nov-2006


Page: 1 2

Related medicine news :

1. MR spectroscopy significantly reduces need for breast biopsy
2. 1.7m to build worlds first SIMS instrument combined with infra-red spectroscopy
3. MR spectroscopy helps identify cancerous breast tumors
4. MR spectroscopy may be superior for determining prostate cancer prognosis
5. WPI wins $1M to develop system to locate and monitor emergency workers in buildings
6. Extreme weather monitoring boosted by space sensor
7. Blood-thinning drugs need closer monitoring
8. Transcontinental wildfire emissions monitored from space
9. New blood test can diagnose and monitor treatment of Parkinsons disease
10. A revolution in the monitoring of unborn babies
11. Remote device allows cardiologist to monitor patients daily at their homes

Post Your Comments:
(Date:7/31/2014)... -- The virus that causes cold sores -- herpes simplex ... symptoms, according to a new study. Researchers in ... people infected with the virus. This explains why some people ... get them only occasionally. The authors said the findings could ... thought when the disease was dormant, it was a truce. ...
(Date:7/31/2014)... York, NY (PRWEB) July 31, 2014 ... Ovarian Cancer Coalition will be featured in the ... space is being donated by EHE International, an ... care management. The eye-catching window display, designed in ... flip-flops symbolizing women’s footsteps, in a ratio that ...
(Date:7/31/2014)... Kansas City, MO (PRWEB) July 31, 2014 ... recently recognized with an Excellence Through Insight award for ... Healthcare Providers and Systems (CG-CAHPS) database in multiple categories ... honor for their commitment to excellence in patient care. ... must have been a patient satisfaction-tracking client of HealthStream ...
(Date:7/31/2014)... July 31, 2014 Six schools of nursing ... for 2014 to 2018, bringing the total to 35, the ... selection is by competitive application reviewed by a panel of ... first-time COE designees. , As in previous years, the new ... Education Summit during the NLN Banquet. Deans and other ...
(Date:7/31/2014)... 2014 Shiitakes have been called “The ... for Quick-Fix Spaghetti Sauce below, they cook up in ... valued for their deep flavor -- four to ten ... of the foods they're cooked with, so they add ... low-fat nutrition. Shiitakes are rich in fiber and contain ...
Breaking Medicine News(10 mins):Health News:Cold Sore Virus Active Without Symptoms, Study Finds 2Health News:National Ovarian Cancer Coalition to be Featured in New York’s Rockefeller Center Window during August to Raise Awareness and Promote Education about Ovarian Cancer 2Health News:National Ovarian Cancer Coalition to be Featured in New York’s Rockefeller Center Window during August to Raise Awareness and Promote Education about Ovarian Cancer 3Health News:Saint Luke’s Health System Physicians and Clinics Earn Excellence through Insight Awards for Overall Patient Experience in the CG-CAHPS Database 2Health News:Saint Luke’s Health System Physicians and Clinics Earn Excellence through Insight Awards for Overall Patient Experience in the CG-CAHPS Database 3Health News:Six Schools of Nursing Named National League for Nursing Centers of Excellence in Nursing Education for 2014-18 2Health News:Six Schools of Nursing Named National League for Nursing Centers of Excellence in Nursing Education for 2014-18 3Health News:Quick Fixin’ Summertime Meals with Shiitake Mushrooms -- Bring ‘em Home and Grow Your Own 2Health News:Quick Fixin’ Summertime Meals with Shiitake Mushrooms -- Bring ‘em Home and Grow Your Own 3
(Date:7/31/2014)... Vermillion, Inc. (NASDAQ: VRML), a multivariate diagnostics company ... conference call on Thursday, August 14, 2014, at 4:30 p.m. ... June 30, 2014. Financial results will be issued in a ... President and CEO James LaFrance will host the ... Date: Thursday, August 14, 2014 Time: 4:30 p.m. Eastern time ...
(Date:7/31/2014)... , July 31, 2014  Today, Levi ... new extension to its PageCenterX ® content ... is designed to provide downtime reporting capabilities to ... LRS is releasing the product for general availability, ... EMR applications experience outages for a variety of ...
(Date:7/31/2014)... WOONSOCKET, R.I. and WASHINGTON ... URAC announced today that CVS/pharmacy is the first ... Community Pharmacy accreditation from URAC, the leading health ... the health care industry. All CVS/pharmacy and Longs ... URAC has over 30 accreditation ...
Breaking Medicine Technology:Vermillion Sets Second Quarter 2014 Conference Call for Thursday, August 14, 2014 2LRS Announces Downtime Reporting Solution for Healthcare 2CVS/pharmacy Earns First-Ever Community Pharmacy Accreditation from URAC 2CVS/pharmacy Earns First-Ever Community Pharmacy Accreditation from URAC 3
Cached News: