HOME >> MEDICINE >> NEWS
High-tech spectroscopy may be used to monitor neuropsychiatric symptoms

WINSTON-SALEM, N.C. Magnetic resonance spectroscopy (MRS) may provide a noninvasive way to monitor neuropsychiatric symptoms in patients with lupus, according to results from research in mice at Wake Forest University School of Medicine.

"This study is the first to demonstrate that MRS is a feasible method to monitor neuropsychiatric symptoms in lupus," said Nilamadhab Mishra, M.D., the principal investigator, in a presentation at the American College of Rheumatology meeting in Washington.

MRS is closely related to MRI (magnetic resonance imaging), and uses strong magnetic fields and low energy radio waves to get biochemical information about the body. The test is done in an MRI machine to which a spectrometer has been attached to measure changes in metabolites, such as the levels of glutamate and glutamine.

"Because of its noninvasiveness and repeatable nature, MRS could be helpful in the drug discovery program for neuropsychiatric lupus," said Mishra, an assistant professor of rheumatology. He explained, "No definitive biomarker of neuropsychiatric lupus is available and this impedes both clinical diagnosis and drug discovery for treatment of this condition."

According to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), in neuropsychiatric lupus, there are a wide variety of associated neurological and psychiatric syndromes and cognitive problems.

NIAMS, which is supporting Mishra's work, said that about 20 percent of lupus patients have neuropsychiatric symptoms and it is one of the major causes of death among people with lupus. Systemic lupus affects an estimated 1.5 million Americans, mostly women.

In his study, Mishra is using mice that have a defective gene and spontaneously develop lupus, including lymph node swelling and increased spleen size. He is comparing these animals with control animals that do not have lupus.

His results showed "a dramatic decrease" in the ratio of two biochemi
'"/>

Contact: Robert Conn
rconn@wfubmc.edu
336-716-4587
Wake Forest University Baptist Medical Center
11-Nov-2006


Page: 1 2

Related medicine news :

1. MR spectroscopy significantly reduces need for breast biopsy
2. 1.7m to build worlds first SIMS instrument combined with infra-red spectroscopy
3. MR spectroscopy helps identify cancerous breast tumors
4. MR spectroscopy may be superior for determining prostate cancer prognosis
5. WPI wins $1M to develop system to locate and monitor emergency workers in buildings
6. Extreme weather monitoring boosted by space sensor
7. Blood-thinning drugs need closer monitoring
8. Transcontinental wildfire emissions monitored from space
9. New blood test can diagnose and monitor treatment of Parkinsons disease
10. A revolution in the monitoring of unborn babies
11. Remote device allows cardiologist to monitor patients daily at their homes

Post Your Comments:
(Date:4/24/2015)... AK (PRWEB) April 24, 2015 As ... (#MOTMC2015) and the unique sacrifices of these young men ... for Service members, Veterans and their Families” presents a ... training is designed to gain a better understanding of ... health and wellness. For those – civilian and military ...
(Date:4/24/2015)... New York, New York (PRWEB) April 24, 2015 ... continue to move forward in the federal ... of South Carolina. According to court documents, the ... Status Report on April 16th detailing, among other ... The report notes that counsel for both plaintiffs ...
(Date:4/24/2015)... Lowcostcarinsuranceprice.com has released a new blog post ... for senior citizens . , Senior citizens may ... mean that they cannot find affordable coverage. By comparing ... the right coverage for their cars at the best ... http://lowcostcarinsuranceprice.com/ provides free leads from various agencies that ...
(Date:4/24/2015)... Vancouver, BC (PRWEB) April 24, 2015 ... Albert Yuzpe, Olive Fertility co-founder and co-director, has been ... Fertility Preservation at the Evening of Hope Gala. ... to recognize Dr. Albert Yuzpe, who has been at ... past 43 years,” says Jessica Séguin, Executive Director of ...
(Date:4/24/2015)... ON (PRWEB) April 24, 2015 ... safe, informed and legal access to medical cannabis, is ... are properly supported when advising patients. , NAC is ... Certificate Program. With a $250,000 grant, NAC will be ... program. , "Our goal is to help Canadians gain ...
Breaking Medicine News(10 mins):Health News:Coalition Presents Resiliency Training to Raise Awareness during Month of the Military Child (#MOTMC2015) 2Health News:Federal Lipitor Lawsuits Progress, as New Status Report Details Preparation for Upcoming Bellwether Trials 2Health News:Federal Lipitor Lawsuits Progress, as New Status Report Details Preparation for Upcoming Bellwether Trials 3Health News:Low Cost Auto Insurance Quotes for Senior Citizens 2Health News:Olive Fertility Centre Co-founder, Dr Al Yuzpe, Recognized as a Pioneer in Fertility Preservation 2Health News:National Access Cannabis Gives 300 Canadian Healthcare Professionals Access to Medical Cannabis Certificate Program 2
(Date:4/24/2015)... 24, 2015  Elekta has CE marked the latest ... system , enabling European clinics to deliver a sophisticated ... including advanced 3D planning, IMRT, VMAT and stereotactic planning ... Monaco ® v5.10 provides ... efficiency. Advancements in 3D planning as well as the ...
(Date:4/23/2015)... -- ResMed Inc. (NYSE: RMD ) today announced results ... the quarter was $422.5 million, a 6 percent increase ... 13 percent increase on a constant currency basis).  Net ... compared to the quarter ended March 31, 2014.  Diluted ... increase of 2 percent compared to the quarter ended ...
(Date:4/23/2015)... FRANCISCO , April 23, 2015 Nektar Therapeutics ... the first quarter ended March 31, 2015 on Thursday, April ... Howard Robin , president and chief executive officer, will host ... p.m. Eastern Time (ET)/2:00 p.m. Pacific Time (PT). ... the conference call can be accessed through a link that ...
Breaking Medicine Technology:Elekta CE marks for Monaco v5.10 treatment planning system 2ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 2ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 3ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 4ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 5ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 6ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 7ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 8ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 9ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 10ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 11ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 12ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 13Nektar to Announce Financial Results for the First Quarter 2015 on Thursday, April 30, 2015, After Close of U.S.-Based Financial Markets 2
Cached News: