HOME >> MEDICINE >> NEWS
High-tech spectroscopy may be used to monitor neuropsychiatric symptoms

WINSTON-SALEM, N.C. Magnetic resonance spectroscopy (MRS) may provide a noninvasive way to monitor neuropsychiatric symptoms in patients with lupus, according to results from research in mice at Wake Forest University School of Medicine.

"This study is the first to demonstrate that MRS is a feasible method to monitor neuropsychiatric symptoms in lupus," said Nilamadhab Mishra, M.D., the principal investigator, in a presentation at the American College of Rheumatology meeting in Washington.

MRS is closely related to MRI (magnetic resonance imaging), and uses strong magnetic fields and low energy radio waves to get biochemical information about the body. The test is done in an MRI machine to which a spectrometer has been attached to measure changes in metabolites, such as the levels of glutamate and glutamine.

"Because of its noninvasiveness and repeatable nature, MRS could be helpful in the drug discovery program for neuropsychiatric lupus," said Mishra, an assistant professor of rheumatology. He explained, "No definitive biomarker of neuropsychiatric lupus is available and this impedes both clinical diagnosis and drug discovery for treatment of this condition."

According to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), in neuropsychiatric lupus, there are a wide variety of associated neurological and psychiatric syndromes and cognitive problems.

NIAMS, which is supporting Mishra's work, said that about 20 percent of lupus patients have neuropsychiatric symptoms and it is one of the major causes of death among people with lupus. Systemic lupus affects an estimated 1.5 million Americans, mostly women.

In his study, Mishra is using mice that have a defective gene and spontaneously develop lupus, including lymph node swelling and increased spleen size. He is comparing these animals with control animals that do not have lupus.

His results showed "a dramatic decrease" in the ratio of two biochemi
'"/>

Contact: Robert Conn
rconn@wfubmc.edu
336-716-4587
Wake Forest University Baptist Medical Center
11-Nov-2006


Page: 1 2

Related medicine news :

1. MR spectroscopy significantly reduces need for breast biopsy
2. 1.7m to build worlds first SIMS instrument combined with infra-red spectroscopy
3. MR spectroscopy helps identify cancerous breast tumors
4. MR spectroscopy may be superior for determining prostate cancer prognosis
5. WPI wins $1M to develop system to locate and monitor emergency workers in buildings
6. Extreme weather monitoring boosted by space sensor
7. Blood-thinning drugs need closer monitoring
8. Transcontinental wildfire emissions monitored from space
9. New blood test can diagnose and monitor treatment of Parkinsons disease
10. A revolution in the monitoring of unborn babies
11. Remote device allows cardiologist to monitor patients daily at their homes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills ... specialty vendors and unique items from across the nation, this holiday-themed event will raise ... offered by the VNA. The boutique will be open Saturday, November 4 (10:00 ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Agile Software Development, has been awarded a contract by the Center for Medicare ... (BPA) aims to accelerate the enterprise use of Agile methodologies in a consistent ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest ... its plans to open a flagship location in Covington, LA at 401 N. U.S. ... Go store next to Office Depot in the Holiday Square shopping center. Its location ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... that we intend to develop to enable prevention of a major side effect ... hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned and Grand Rapids-based ... and Brightest in Wellness® by Best and Brightest. OnSite Wellness will be honored ... 20 from 7:30 a.m. to 2 p.m. at the Henry Autograph Collection Hotel, ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... , Oct. 2, 2017  AllianceRx Walgreens Prime, ... formed by Walgreens and pharmacy benefit manager Prime Therapeutics ... new brand, which included the unveiling of new signage ... , as well as at a few other company-owned ... new brand to patients, some of whom will begin ...
(Date:9/27/2017)... for their devotion to personalized service, SMP Pharmacy Solutions announces ... the South Florida Business Journal,s 50 Fastest-Growing Companies, and listed ... national specialty pharmacy has found its niche.  To that end, ... honored by SFBJ as the 2017 Power Leader in Health ... his award in October, Bardisa said of the three achievements, ...
(Date:9/22/2017)... , Sept. 22, 2017  As the latest ... Senators Bill Cassidy (R-LA) and Lindsey ... notes that the medical device industry is in an ... device tax, the 2.3% excise tax on medical device ... they also want covered patients, increased visits and hospital ...
Breaking Medicine Technology:
Cached News: