HOME >> MEDICINE >> NEWS
High-tech spectroscopy may be used to monitor neuropsychiatric symptoms

WINSTON-SALEM, N.C. Magnetic resonance spectroscopy (MRS) may provide a noninvasive way to monitor neuropsychiatric symptoms in patients with lupus, according to results from research in mice at Wake Forest University School of Medicine.

"This study is the first to demonstrate that MRS is a feasible method to monitor neuropsychiatric symptoms in lupus," said Nilamadhab Mishra, M.D., the principal investigator, in a presentation at the American College of Rheumatology meeting in Washington.

MRS is closely related to MRI (magnetic resonance imaging), and uses strong magnetic fields and low energy radio waves to get biochemical information about the body. The test is done in an MRI machine to which a spectrometer has been attached to measure changes in metabolites, such as the levels of glutamate and glutamine.

"Because of its noninvasiveness and repeatable nature, MRS could be helpful in the drug discovery program for neuropsychiatric lupus," said Mishra, an assistant professor of rheumatology. He explained, "No definitive biomarker of neuropsychiatric lupus is available and this impedes both clinical diagnosis and drug discovery for treatment of this condition."

According to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), in neuropsychiatric lupus, there are a wide variety of associated neurological and psychiatric syndromes and cognitive problems.

NIAMS, which is supporting Mishra's work, said that about 20 percent of lupus patients have neuropsychiatric symptoms and it is one of the major causes of death among people with lupus. Systemic lupus affects an estimated 1.5 million Americans, mostly women.

In his study, Mishra is using mice that have a defective gene and spontaneously develop lupus, including lymph node swelling and increased spleen size. He is comparing these animals with control animals that do not have lupus.

His results showed "a dramatic decrease" in the ratio of two biochemi
'"/>

Contact: Robert Conn
rconn@wfubmc.edu
336-716-4587
Wake Forest University Baptist Medical Center
11-Nov-2006


Page: 1 2

Related medicine news :

1. MR spectroscopy significantly reduces need for breast biopsy
2. 1.7m to build worlds first SIMS instrument combined with infra-red spectroscopy
3. MR spectroscopy helps identify cancerous breast tumors
4. MR spectroscopy may be superior for determining prostate cancer prognosis
5. WPI wins $1M to develop system to locate and monitor emergency workers in buildings
6. Extreme weather monitoring boosted by space sensor
7. Blood-thinning drugs need closer monitoring
8. Transcontinental wildfire emissions monitored from space
9. New blood test can diagnose and monitor treatment of Parkinsons disease
10. A revolution in the monitoring of unborn babies
11. Remote device allows cardiologist to monitor patients daily at their homes

Post Your Comments:
(Date:7/1/2015)... ... ... a disorder in which the normally straight vertical line of the spine curves to one ... population, or an estimated 6 to 9 million people. While it is found in people ... 15. Most types of scoliosis are more common in girls than in boys. When a ...
(Date:7/1/2015)... NC (PRWEB) , ... July 01, 2015 , ... ... 2013 mesothelioma compensation law has just published a top ten list they hope ... the report. Click here to read it now. , More ...
(Date:7/1/2015)... ... ... B. E. Smith, the only full-service leadership solutions firm dedicated exclusively to ... for Capital Health in Pennington, N.J. One of the top ... more than 1,000 healthcare executives into organizations. , Capital Health is a two-hospital ...
(Date:7/1/2015)... (PRWEB) , ... July 01, 2015 , ... Research published ... Kit (Peek) smartphone app to test eyesight was just as accurate as those from ... of Hygiene and Tropical Medicine is responsible for the development of the test, which ...
(Date:7/1/2015)... Newport Beach, CA (PRWEB) , ... July 01, ... ... Orrick has returned to the Northbound team as Director of Referral Relations. ... two programs, including Northbound’s Collegebound, where she designed and implemented unique academic curriculum ...
Breaking Medicine News(10 mins):Health News:Scoliosis: A Guide for Parents from Orthopedic Surgeon Dr. Fabien Bitan 2Health News:Scoliosis: A Guide for Parents from Orthopedic Surgeon Dr. Fabien Bitan 3Health News:Scoliosis: A Guide for Parents from Orthopedic Surgeon Dr. Fabien Bitan 4Health News:New Report Identifies Top 10 Mesothelioma Research Priorities, According to Surviving Mesothelioma 2Health News:Capital Health Retains B. E. Smith to Recruit New Chief Nursing Officer 2Health News:Capital Health Retains B. E. Smith to Recruit New Chief Nursing Officer 3Health News:New Research Shows Reliability of Peek Eye Testing Mobile App 2Health News:New Research Shows Reliability of Peek Eye Testing Mobile App 3Health News:Northbound Treatment Services Welcomes Emily Orrick as Director of Referral Relations 2
(Date:7/1/2015)... Pa. , July 1, 2015 ... fully integrated specialty pharmaceutical company focused on developing, ... that Bob Radie , president and chief ... conferences this summer. He will provide an update ... (ketorolac tromethamine) Nasal Spray, approved product ...
(Date:7/1/2015)... July 1, 2015 New exchange plan enrollees ... 2015 compared to the same time a year ago, ... (NASDAQ: ESRX ) Exchange Pulse™ report, released today. ... 2014, the number of new exchange plan enrollees who ... in the first quarter of 2015. However, when evaluating ...
(Date:7/1/2015)... The Haselmeier Group has decided ... Gert Weber has been nominated by the Board ... Executive Officer (CEO) of the Haselmeier Group. This ... Mr. Weber brings more than 20 years of experience ... various executive management positions, the last being Managing Director ...
Breaking Medicine Technology:Egalet to Present at Upcoming Conferences This Summer 2Egalet to Present at Upcoming Conferences This Summer 3Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 2Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 3Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 4Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 5Haselmeier Group Announces the Extension and Reorganization of its Executive Board 2
Cached News: