HOME >> MEDICINE >> NEWS
Higher placental weight associated with increased maternal breast cancer risk

n who had placentas weighing less than 500 g in 2 consecutive pregnancies, the risk of breast cancer was increased among women whose placentas weighed between 500 and 699 g in their first pregnancy and at least 700 g in their second pregnancy (or vice versa), and the corresponding risk was doubled among women whose placentas weighed at least 700 g in both pregnancies. A high birth weight (4000 g or greater) in 2 successive births was associated with an increased risk of breast cancer before but not after adjusting for placental weight and other covariates. Compared with women who had a placental weight of less than 500 g, women who had a placental weight of at least 700 g had a 38 percent increase in risk of breast cancer.

"Our finding of a positive association between placental weight and breast cancer risk may reflect that exposures to elevated levels of pregnancy hormones influence the risk of breast cancer. The role of estrogens in breast carcinogenesis is well established, and serum estrogen levels are at least 10 times higher during pregnancy compared with other times of life," the authors write.

"In addition, placental weight appears to be a better indicator of the hormonal milieu than birth weight or other included birth parameters. Underlying biological mechanisms responsible for the observed associations may not only be limited to a direct growth enhancing effect on breast cells during childbearing, but also may be due to maternal characteristics or genetic factors associated with placental growth," the researchers conclude. (JAMA.2005; 294:2474-2480. Available pre-embargo to the media at www.jamamedia.org)


'"/>

Contact: Sven Cnattingius, M.D., Ph.D.
sven.cnattingius@mep.ki.se
JAMA and Archives Journals
15-Nov-2005


Page: 1 2

Related medicine news :

1. Higher intake of fish and vitamin D levels linked to lower risk of age-related macular disease
2. Higher gas prices leave many workers running on empty
3. Higher calcium and vitamin D intakes positively associated with brain lesions in older men and women
4. Higher physical activity associated with reduced risk of breast cancer
5. Higher levels of cells originating in bone marrow may be useful in prognosis of liver cancer
6. Higher blood pressure associated with decline in walking ability in older persons
7. Higher levels of obesity associated with greater health risks
8. Higher death rates associated with increasing degrees of obesity, PITT researchers report
9. Higher strength MRI can help patients avoid arthroscopy for shoulder injuries
10. Higher self-awareness of memory complaints predict brain function decline
11. Higher rates of infection may explain why women have higher risk of death after bypass surgery

Post Your Comments:
(Date:4/19/2015)... 2015 Carinsurancehints.com has released a new blog ... claim auto insurance benefits . , Drivers who ... all the necessary information for claiming auto insurance benefits. Exchanging ... plan to cover most of the damages. The newly released ... an accident. , Drivers can compare online rates and ...
(Date:4/19/2015)... April 19, 2015 The American Institute ... with PROSHRED Security (“PROSHRED”) to host its second annual, ... shred their personal documents in order to raise funds ... , The June 6th event is being held at ... 2pm local time. The time will vary at select ...
(Date:4/19/2015)... HealthPostures, LLC , a leading ... exhibit it’s pioneering ergonomics products at the Wisconsin Safety ... Council Professional Development Conference and Expo . The products, ... used in volume by call centers, educational organizations, retailers, ... clamp to a desk, the TaskMate Go 6350 and ...
(Date:4/18/2015)... Carinsurancesavings.biz has released a new blog post explaining ... Spring. , Spring can be a great season ... sure they compare the newest policies before deciding on ... about Spring car insurance offers by reading the newly ... becoming more and more popular. Many insurance brokerage websites ...
(Date:4/18/2015)... Insuranceautoquote.info has released a new blog post ... . , Clients can review important auto insurance ... environment provides important advantages for clients who need affordable ... do not have coverage for their vehicles can purchase ... or hour. Many agencies offer important discounts and drivers ...
Breaking Medicine News(10 mins):Health News:An Online Guide About Claiming Auto Insurance Benefits After an Accident 2Health News:2015 Annual Nationwide "Shred Cancer" Shredding Event 2Health News:HealthPostures' TaskMate Products to be Exhibited at the Wisconsin and Iowa-Illinois Safety Conferences 2Health News:Auto Insurance Plans Are Cheaper During Spring! 2Health News:Clients Can Review Car Insurance Quotes Online To Find Low Cost Offers! 2
(Date:4/17/2015)... - The issue: In consultation ... lot (lot 710535) of Clavulin-400 (70mL) after receiving a complaint ... in one bottle of the  product. No other lots of ... Clavulin-400 is an oral antibiotic used in adults and children ... Clavulin-400 comes as a powder in bottles and is mixed ...
(Date:4/17/2015)... , April 17, 2015 Contego ... Integrated Embolic Protection™ filter platform for angioplasty balloon ... a $5.6 million Series B financing round led ... firm with a focus on medical devices, biopharmaceuticals, ... round also included Mountain Group Partners, Lookout Capital ...
(Date:4/17/2015)... April 17, 2015  Regulatory leaders in the pharmaceutical ... discussion draft called "21 st Century Cures." ... be taken up by Congress soon and if enacted ... device products are developed and marketed in ... companies have begun to consider how the proposed changes ...
Breaking Medicine Technology:Advisory - Clavulin-400 liquid oral antibiotic: One lot recalled after glass pieces found in one bottle 2Contego Medical Closes $5.6 Million in Series B Funding 2Contego Medical Closes $5.6 Million in Series B Funding 321st Century Cures: A Regulatory Game-Changer for the Pharmaceutical Industry 2
Cached News: