HOME >> MEDICINE >> NEWS
Higher placental weight associated with increased maternal breast cancer risk

n who had placentas weighing less than 500 g in 2 consecutive pregnancies, the risk of breast cancer was increased among women whose placentas weighed between 500 and 699 g in their first pregnancy and at least 700 g in their second pregnancy (or vice versa), and the corresponding risk was doubled among women whose placentas weighed at least 700 g in both pregnancies. A high birth weight (4000 g or greater) in 2 successive births was associated with an increased risk of breast cancer before but not after adjusting for placental weight and other covariates. Compared with women who had a placental weight of less than 500 g, women who had a placental weight of at least 700 g had a 38 percent increase in risk of breast cancer.

"Our finding of a positive association between placental weight and breast cancer risk may reflect that exposures to elevated levels of pregnancy hormones influence the risk of breast cancer. The role of estrogens in breast carcinogenesis is well established, and serum estrogen levels are at least 10 times higher during pregnancy compared with other times of life," the authors write.

"In addition, placental weight appears to be a better indicator of the hormonal milieu than birth weight or other included birth parameters. Underlying biological mechanisms responsible for the observed associations may not only be limited to a direct growth enhancing effect on breast cells during childbearing, but also may be due to maternal characteristics or genetic factors associated with placental growth," the researchers conclude. (JAMA.2005; 294:2474-2480. Available pre-embargo to the media at www.jamamedia.org)


'"/>

Contact: Sven Cnattingius, M.D., Ph.D.
sven.cnattingius@mep.ki.se
JAMA and Archives Journals
15-Nov-2005


Page: 1 2

Related medicine news :

1. Higher intake of fish and vitamin D levels linked to lower risk of age-related macular disease
2. Higher gas prices leave many workers running on empty
3. Higher calcium and vitamin D intakes positively associated with brain lesions in older men and women
4. Higher physical activity associated with reduced risk of breast cancer
5. Higher levels of cells originating in bone marrow may be useful in prognosis of liver cancer
6. Higher blood pressure associated with decline in walking ability in older persons
7. Higher levels of obesity associated with greater health risks
8. Higher death rates associated with increasing degrees of obesity, PITT researchers report
9. Higher strength MRI can help patients avoid arthroscopy for shoulder injuries
10. Higher self-awareness of memory complaints predict brain function decline
11. Higher rates of infection may explain why women have higher risk of death after bypass surgery

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2016)... Oakland, California (PRWEB) , ... May 26, 2016 ... ... liabilities associated with discovery of thousands of defective respirators, according to court documents ... in the case of William and Becky Tyler v. American Optical Corporation, Case ...
(Date:5/26/2016)... ... ... On Memorial Day, Hope For Heroes and USA Medical Card will ... country. The nonprofit Hope For Heroes partnered with the leading provider of free ... military veterans, as well as police, firemen, and EMS professionals across the country, and ...
(Date:5/26/2016)... Hampshire (PRWEB) , ... May 26, 2016 , ... MadgeTech ... are designed, engineered, and manufactured in Warner, New Hampshire at the MadgeTech headquarters. With ... provide reliable monitoring solutions trusted by government agencies, including NASA. , In 2012, ...
(Date:5/26/2016)... ... 2016 , ... In an effort to provide hair restoration information to the widest possible audience, ... who do not use the app. Dr. Mohebi, the founder of Parsa Mohebi Hair Restoration, ... . , Dr. Mohebi says, “The positive response to the Snapchat videos we started ...
(Date:5/26/2016)... ... ... The Lung Institute has partnered with the Gulfcoast North Area Health ... their clinic in downtown Tampa. The class is complimentary for the public. Register online ... free downloadable 4 Week Smoking Cessation Guide for those who are unable ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... 26, 2016 Since its commercial ... an essential life science tool for conducting genetic studies ... Research reveals in its new report that the industry ... one powered by a range of new applications in ... (Logo: http://photos.prnewswire.com/prnh/20140723/694805 ) , Since ...
(Date:5/25/2016)... According to a new market ... 4D), by Therapeutic Area (Oncology, Cosmeceutical/Plastic Surgery), by Application ... Manufacturers, Hospitals/ Clinics) - Forecast to 2021", published by ... for the forecast period of 2016 to 2021. This ... 2021 from USD 117.3 Million in 2016, at a ...
(Date:5/25/2016)... Germany and GERMANTOWN, Maryland ... N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: QIA) ... and co-development agreement with Therawis Diagnostics GmbH to develop and ... to develop and market PITX2 as a marker to predict ... breast cancer patients. "We are pleased to partner ...
Breaking Medicine Technology:
Cached News: