HOME >> MEDICINE >> NEWS
Higher placental weight associated with increased maternal breast cancer risk

n who had placentas weighing less than 500 g in 2 consecutive pregnancies, the risk of breast cancer was increased among women whose placentas weighed between 500 and 699 g in their first pregnancy and at least 700 g in their second pregnancy (or vice versa), and the corresponding risk was doubled among women whose placentas weighed at least 700 g in both pregnancies. A high birth weight (4000 g or greater) in 2 successive births was associated with an increased risk of breast cancer before but not after adjusting for placental weight and other covariates. Compared with women who had a placental weight of less than 500 g, women who had a placental weight of at least 700 g had a 38 percent increase in risk of breast cancer.

"Our finding of a positive association between placental weight and breast cancer risk may reflect that exposures to elevated levels of pregnancy hormones influence the risk of breast cancer. The role of estrogens in breast carcinogenesis is well established, and serum estrogen levels are at least 10 times higher during pregnancy compared with other times of life," the authors write.

"In addition, placental weight appears to be a better indicator of the hormonal milieu than birth weight or other included birth parameters. Underlying biological mechanisms responsible for the observed associations may not only be limited to a direct growth enhancing effect on breast cells during childbearing, but also may be due to maternal characteristics or genetic factors associated with placental growth," the researchers conclude. (JAMA.2005; 294:2474-2480. Available pre-embargo to the media at www.jamamedia.org)


'"/>

Contact: Sven Cnattingius, M.D., Ph.D.
sven.cnattingius@mep.ki.se
JAMA and Archives Journals
15-Nov-2005


Page: 1 2

Related medicine news :

1. Higher intake of fish and vitamin D levels linked to lower risk of age-related macular disease
2. Higher gas prices leave many workers running on empty
3. Higher calcium and vitamin D intakes positively associated with brain lesions in older men and women
4. Higher physical activity associated with reduced risk of breast cancer
5. Higher levels of cells originating in bone marrow may be useful in prognosis of liver cancer
6. Higher blood pressure associated with decline in walking ability in older persons
7. Higher levels of obesity associated with greater health risks
8. Higher death rates associated with increasing degrees of obesity, PITT researchers report
9. Higher strength MRI can help patients avoid arthroscopy for shoulder injuries
10. Higher self-awareness of memory complaints predict brain function decline
11. Higher rates of infection may explain why women have higher risk of death after bypass surgery

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... Lewisville, TX (PRWEB) , ... June 25, 2016 , ... ... in the United States, named Dr. Sesan Ogunleye, as the Medical Director of its ... be the facility Medical Director of our new Mesquite location,” said Dr. James M. ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... PASADENA, CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. ... he would lash out at his family verbally and physically. , “When something upset him, ... table, he would use it. He would throw rocks at my other children and say ...
(Date:6/24/2016)... ... ... Comfort Keepers® of San Diego, CA is excited to announce they are ... drive cancer patients to and from their cancer treatments. Comfort Keepers provides quality ... and ongoing independence. Getting to and from medical treatments is one of the ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty ... Barry M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... and the most handsome men, look naturally attractive. Plastic surgery should be invisible.” ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016  Experian Health, the ... transforming the patient payment and care experience, ... new products and services that will enhance ... cycle offerings. These award-winning solutions will enable ... remain compliant in an ever-changing environment and ...
(Date:6/23/2016)... 23, 2016  The National Pharmaceutical Council (NPC) ... health policy research organization as its newest member.  ... senior vice president and chief scientific officer, Mallinckrodt ... the NPC Board of Directors. ... has joined us in support of our efforts ...
(Date:6/23/2016)... 2016  Delcath Systems, Inc. (NASDAQ: DCTH ... on treatment of primary and metastatic liver cancers, announces ... - www.againsttheodds.eu - has been awarded a ... The website was developed as ... their families who are coping with the devastating diagnosis ...
Breaking Medicine Technology:
Cached News: