HOME >> MEDICINE >> NEWS
Hopkins researchers identify risk factors for prediction of lethal prostate cancer after recurrence

Researchers at Johns Hopkins and The Brady Urological Institute have identified three risk factors and developed a simple reference tool that doctors can use to determine who is at high risk of death after prostate cancer recurrence following surgery. The new tool - a set of tables that assess a combination of blood tests, the surgical pathology results and time following surgery - can be used to tell which men with recurring cancer after surgery are most likely to die from their renewed disease and would benefit from further treatment.

"We identified three risk factors associated with death from prostate cancer after recurrence that may allow doctors to distinguish early on between those who need further treatment versus those who are relatively safe and can be carefully watched," says Stephen J. Freedland, M.D., instructor of urology at Johns Hopkins and lead investigator of the report published in the July 27, 2005, issue of the Journal of the American Medical Association.

If discovered early through screening, prostate cancer is treatable and is often cured by a surgical procedure called radical prostatectomy. However, as many as one-third of those who undergo surgery will eventually show signs that the cancer has recurred, said Freedland.

The risk factors are based on:

  • The amount of time, in months, it takes the level of prostate-specific antigen (PSA) in the blood to double after surgery. The shorter the time, the higher the risk.
  • The elapsed time, in years, from surgery to recurrence as measured by the PSA test. Again, the shorter the time the higher the risk.
  • The Gleason score (2-10), a microscopic measurement of prostate cancer aggressiveness when viewed under a microscope. Higher scores reflect more aggressive tumors.

An additional finding was that time to death after recurrence for patients in the low-risk group was quite long -- often much longer than 16 years, added Freedland.

To
'"/>

Contact: Trent Stockton
tstockt1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
26-Jul-2005


Page: 1 2

Related medicine news :

1. Johns Hopkins begins aggressive screening for superbugs in children
2. Johns Hopkins develops pancreas cancer risk model
3. Hopkins study reveals white blood cells can both hurt and help transplanted kidneys
4. Hopkins scientists link immune response to ghost parasites and severely congested sinuses
5. Hopkins-led study finds that chronic form of depression runs in families
6. Diagnosis and referrals for kidney disease fall well short of need, Johns Hopkins study shows
7. Johns Hopkins Childrens Center to lead largest-ever study on kidney disease in children
8. Hopkins scientists show hallucinogen in mushrooms creates universal mystical experience
9. Johns Hopkins lab scientists tame overactive CF protein
10. Hopkins researchers develop new quick tool to sort out insect bites in children
11. Hopkins scientists use embryonic stem cells, new cues to awaken latent motor nerve repair

Post Your Comments:
(Date:7/7/2015)... ... July 07, 2015 , ... Dr. Poneh Ghasri ... whitening treatments. A professional teeth whitening is one of the fastest, easiest ways to ... as they can decrease smile satisfaction and confidence. With the right teeth whitening treatment, ...
(Date:7/7/2015)... CA (PRWEB) , ... July 07, 2015 , ... America ... others. California Casualty’s Nominate A Hero program offers a special way to ... a well-deserving hero receives a $250 gift card and their place on the “Wall ...
(Date:7/7/2015)... ... July 07, 2015 , ... Office ... the company’s new Chief Financial Officer, effective July 6th, 2015. Ellen joins Office ... ranging from a multi-billion dollar, global chemical company to early and growth-stage technology ...
(Date:7/7/2015)... ... July 07, 2015 , ... ... motivated leaders with strong managerial expertise to oversee large healthcare operations and ... staff, providers, business partners, insurance companies, and regulators. American Sentinel University, an ...
(Date:7/7/2015)... IL (PRWEB) , ... July ... ... Inc., a leading provider of unified communication management solutions, has announced the ... Infortel® Select. , This service pack includes a number of enhancements to ...
Breaking Medicine News(10 mins):Health News:Los Angeles Cosmetic Dentist, Poneh Ghasri DDS, Now Offers Promotions on Whitening Treatments 2Health News:Los Angeles Cosmetic Dentist, Poneh Ghasri DDS, Now Offers Promotions on Whitening Treatments 3Health News:California Casualty Wants to Know: "Who Is Your Hero?" 2Health News:Office Practicum Announces new CFO 2Health News:American Sentinel University Details Six Ways Healthcare Leaders Can Sharpen Communications Skills 2Health News:American Sentinel University Details Six Ways Healthcare Leaders Can Sharpen Communications Skills 3Health News:American Sentinel University Details Six Ways Healthcare Leaders Can Sharpen Communications Skills 4Health News:ISI Telemanagement Solutions, Inc. Releases Service Pack 5600 for Infortel® Select 2
(Date:7/7/2015)... , July 7, 2015  Essentialis, a venture-backed company ... for the treatment of orphan neurobehavioral and metabolic diseases, today ... CSO, will present a corporate update at the Cantor Fitzgerald ... Date: Wednesday, July 8, 2015 Time: 8:00 ... About Essentialis, Inc. Essentialis ...
(Date:7/7/2015)... , July 7, 2015 Oramed ... a clinical-stage pharmaceutical company focused on the development of ... signed a non-binding Letter of Intent (LoI) for an ... with Sinopharm Capital Management Co. Ltd. and Hefei ... Ltd. (Sinopharm/ Hefei ) potentially valued at ...
(Date:7/6/2015)... July 6, 2015  Student-athletes at community colleges ... from a recently established partnership between ImPACT Applications, ... . The partnership enables member institutions of ... ImPACT ® concussion baseline and post-injury testing ... of community colleges in California ...
Breaking Medicine Technology:Sinopharm Capital-Hefei Signs Letter of Intent with Oramed for $50,000,000 Investment and Licensing Deal in China 2Sinopharm Capital-Hefei Signs Letter of Intent with Oramed for $50,000,000 Investment and Licensing Deal in China 3Sinopharm Capital-Hefei Signs Letter of Intent with Oramed for $50,000,000 Investment and Licensing Deal in China 4Sinopharm Capital-Hefei Signs Letter of Intent with Oramed for $50,000,000 Investment and Licensing Deal in China 5California Community College Athletic Departments to Benefit from ImPACT Concussion Baseline Testing Offered by Student Insurance 2California Community College Athletic Departments to Benefit from ImPACT Concussion Baseline Testing Offered by Student Insurance 3
Cached News: