HOME >> MEDICINE >> NEWS
Hopkins researchers identify risk factors for prediction of lethal prostate cancer after recurrence

Researchers at Johns Hopkins and The Brady Urological Institute have identified three risk factors and developed a simple reference tool that doctors can use to determine who is at high risk of death after prostate cancer recurrence following surgery. The new tool - a set of tables that assess a combination of blood tests, the surgical pathology results and time following surgery - can be used to tell which men with recurring cancer after surgery are most likely to die from their renewed disease and would benefit from further treatment.

"We identified three risk factors associated with death from prostate cancer after recurrence that may allow doctors to distinguish early on between those who need further treatment versus those who are relatively safe and can be carefully watched," says Stephen J. Freedland, M.D., instructor of urology at Johns Hopkins and lead investigator of the report published in the July 27, 2005, issue of the Journal of the American Medical Association.

If discovered early through screening, prostate cancer is treatable and is often cured by a surgical procedure called radical prostatectomy. However, as many as one-third of those who undergo surgery will eventually show signs that the cancer has recurred, said Freedland.

The risk factors are based on:

  • The amount of time, in months, it takes the level of prostate-specific antigen (PSA) in the blood to double after surgery. The shorter the time, the higher the risk.
  • The elapsed time, in years, from surgery to recurrence as measured by the PSA test. Again, the shorter the time the higher the risk.
  • The Gleason score (2-10), a microscopic measurement of prostate cancer aggressiveness when viewed under a microscope. Higher scores reflect more aggressive tumors.

An additional finding was that time to death after recurrence for patients in the low-risk group was quite long -- often much longer than 16 years, added Freedland.

To
'"/>

Contact: Trent Stockton
tstockt1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
26-Jul-2005


Page: 1 2

Related medicine news :

1. Johns Hopkins begins aggressive screening for superbugs in children
2. Johns Hopkins develops pancreas cancer risk model
3. Hopkins study reveals white blood cells can both hurt and help transplanted kidneys
4. Hopkins scientists link immune response to ghost parasites and severely congested sinuses
5. Hopkins-led study finds that chronic form of depression runs in families
6. Diagnosis and referrals for kidney disease fall well short of need, Johns Hopkins study shows
7. Johns Hopkins Childrens Center to lead largest-ever study on kidney disease in children
8. Hopkins scientists show hallucinogen in mushrooms creates universal mystical experience
9. Johns Hopkins lab scientists tame overactive CF protein
10. Hopkins researchers develop new quick tool to sort out insect bites in children
11. Hopkins scientists use embryonic stem cells, new cues to awaken latent motor nerve repair

Post Your Comments:
(Date:12/20/2014)... has recently announced its new collection of sweet 16 ... dresses for the coming new year. , Weddingshe.com ... global women. Now, all the models on its website ... Among the new items, the model of 10986064 (Fresh ... popular. What’s more, Weddingshe.com also provides a fast and ...
(Date:12/20/2014)... The holidays can be anything but joyous for people ... candles and other allergy triggers. "The dust from ... packed away in dank basements or dusty attics is ... Rachna Shah, an affiliate faculty member at Loyola University ... release. Shah, who is also an allergist at ...
(Date:12/20/2014)... December 20, 2014 Atore, Inc, (San ... just launched first birthday focused portal on December 17th, ... MESSAGE” launched in both US and Japan. , MERRY ... : http://merrybirthday.net/message/ , MERRY BIRTHDAY MESSAGE is ... around the world. , Features, Choose from thousands of ...
(Date:12/20/2014)... (PRWEB) December 20, 2014 The Twin ... protection education event in the nation! Over 250 financial ... the minute information on the industry, get motivated to ... of real people facing and overcoming the challenges of ... all across the nation came together to attend The ...
(Date:12/19/2014)... Sweetdressy.com , a leading wedding dress manufacturer ... of cheap prom dresses for ladies worldwide. The prom ... and clients can buy these dresses at the website ... cool cuts and delicate craftsmanship, and most of them ... Discount shipping costs are available for all of their ...
Breaking Medicine News(10 mins):Health News:Tons of New-in Winter Sweet 16 Dresses from Weddingshe Online Now 2Health News:Holiday Trimmings Can Trigger Allergies 2Health News:Atore, Inc. Releasing the First Birthday Portal 2Health News:The 13th Annual Twin Cities DI Day Now On Video 2Health News:The 13th Annual Twin Cities DI Day Now On Video 3Health News:Cheap Prom Dresses Online Now at Sweetdressy.com 2
(Date:12/17/2014)... AMSTERDAM and SAN DIEGO , ... PHG ; AEX: PHIA) and Volcano Corporation (NASDAQ: ... and measurement solutions for cardiovascular applications, today announced that they ... agreement, Philips will commence a tender offer to acquire all ... 18.00 per share, or a total equity purchase price of ...
(Date:12/17/2014)... Germany , December 17, 2014 ... level of expenditure on research and development In ... increased its revenue by two percent to EUR 4.287 billion ... (EBIT) grew by 14 percent to EUR 360 million. "Overall, ... said Dr. Michael Kaschke , President and CEO of ...
(Date:12/17/2014)... 17, 2014  Northstar Global Business Services, Inc. ... (DTC) has made their final decision and has ... Company,s stock effective December 15, 2014, and has ... depository and book entry transfer services. All deposit restrictions ... once again fully "DTC Eligible", and has resumed ...
Breaking Medicine Technology:Philips to acquire Volcano to expand global leadership position in image-guided therapy market 2Philips to acquire Volcano to expand global leadership position in image-guided therapy market 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 4Philips to acquire Volcano to expand global leadership position in image-guided therapy market 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 6Philips to acquire Volcano to expand global leadership position in image-guided therapy market 7Philips to acquire Volcano to expand global leadership position in image-guided therapy market 8ZEISS Asserts its Position in Difficult Environment 2Northstar announces that the DTC chill on MDIN has been officially lifted 2Northstar announces that the DTC chill on MDIN has been officially lifted 3
Cached News: