Hormone use linked to increased breast cancer risk among b...( reased risk of breast cancer are biolog...),Health

reased risk of breast cancer are biologically plausible," the authors write. Estrogens produced by the body are associated with the development of breast cancer, and progestin is known to induce cell division in breast tissue, which could lead to a higher risk of cancer. The relationship may be stronger in lean women because fat tissue produces estrogen, so the extra hormones added by taking pills may not have as much of an effect on estrogen levels in heavier women.

"These results based on data from U.S. black women strengthen the evidence that use of estrogen alone and estrogen with progestin increases the risk of breast cancer and that the association is stronger among leaner women," the authors conclude.

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Contact: Lisa Brown
617-414-1401
JAMA and Archives Journals
10-Apr-2006

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