How does Mycobacterium tuberculosis infect...( shortly after infection not only the i...)

How does Mycobacterium tuberculosis infect the lung?

shortly after infection not only the infected cells but also some of their neighbours started to display DC-SIGN on their surface. They also found that having DC-SIGN on the surface made uninfected cells much more susceptible to infection.

These results suggest that DC-SIGN has an important function in amplifying TB infection in the lung. Interfering with DC-SIGN function might therefore be a new way to fight TB, a disease that is becoming increasingly resistant to existing therapies and for which new drugs are urgently needed.

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Contact: Paul Ocampo
press@plos.org
415-624-1224
Public Library of Science
14-Nov-2005

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How does Mycobacterium tuberculosis infect...( shortly after infection not only the i...),Health